Search Results - "Guenter, Rachael"

A hitchhiker’s guide to cancer models by Budhwani, Karim I., Patel, Zeelu H., Guenter, Rachael E., Charania, Areesha A.

“…Cancer is a complex and uniquely personal disease. More than 1.7 million people in the United States are diagnosed with cancer every year. As the burden of…”
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Preclinical safety evaluation of continuous UV-A lighting in an operative setting by Guenter, Rachael, Zheng-Pywell, Rui, Herring, Brendon, Murphy, Madisen, Foote, Jeremy, Benner, Kevin, Rose, J Bart

“…Germicidal ultraviolet (UV-C) light has been shown as an effective modality for disinfection in laboratory settings and in the operative room. Traditionally,…”
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Notch Signaling in Vascular Endothelial Cells, Angiogenesis, and Tumor Progression: An Update and Prospective by Akil, Abdellah, Gutiérrez-García, Ana K, Guenter, Rachael, Rose, J Bart, Beck, Adam W, Chen, Herbert, Ren, Bin

“…The Notch signaling pathway plays an essential role in a wide variety of biological processes including cell fate determination of vascular endothelial cells…”
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Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors by Guenter, Rachael E, Aweda, Tolulope, Carmona Matos, Danilea M, Whitt, Jason, Chang, Alexander W, Cheng, Eric Y, Liu, X Margaret, Chen, Herbert, Lapi, Suzanne E, Jaskula-Sztul, Renata

“…Pulmonary carcinoids are a type of neuroendocrine tumor (NET) accounting for 1-2% of lung cancer cases. Currently, Positron Emission Tomography (PET)/CT based…”
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Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors by Carter, Angela M., Kumar, Nilesh, Herring, Brendon, Tan, Chunfeng, Guenter, Rachael, Telange, Rahul, Howse, Wayne, Viol, Fabrice, McCaw, Tyler R., Bickerton, Hayden H., Gupta, Priyanka, Gillardon, Frank, Woltering, Eugene A., Dhall, Deepti, Totenhagen, John, Banerjee, Ronadip R., Kurian, Elizabeth M., Reddy, Sushanth, Chen, Herbert, Schrader, Joerg, Bart Rose, J., Mukhtar, M. Shahid, Bibb, James A.

“…Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous population of neoplasms that arise from hormone-secreting islet cells of the pancreas and have…”
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Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling by Jiang, Yinan, Guo, Yichen, Hao, Jinjin, Guenter, Rachael, Lathia, Justin, Beck, Adam W., Hattaway, Reagan, Hurst, Douglas, Wang, Qiming Jane, Liu, Yehe, Cao, Qi, Krontiras, Helen, Chen, Herbert, Silverstein, Roy, Ren, Bin

“…Breast cancer stem cells (BCSCs) are essential for cancer growth, metastasis and recurrence. The regulatory mechanisms of BCSC interactions with the vascular…”
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Under-Representation of Racial Groups in Genomics Studies of Gastroenteropancreatic Neuroendocrine Neoplasms by Herring, Brendon R, Bonner, Andrew, Guenter, Rachael E, Vickers, Selwyn, Yates, Clayton, Lee, Goo, Dhall, Deepti, Chen, Herbert, Rose, J Bart

“…Not all populations are poised to benefit from advancing genomics in gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN), as genomics have focused on…”
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Notch Signaling in Thyroid Cancer by Guenter, Rachael, Patel, Zeelu, Chen, Herbert

“…Thyroid cancer is the most common malignancy of the endocrine system with a steadily rising incidence. The term "thyroid cancer" encompasses a spectrum of…”
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Upregulation of Somatostatin Receptor 2 in Neuroendocrine Tumors Using Histone Deacetylase Inhibitors by Guenter, Rachael

“…Neuroendocrine cancer is complex disease of the diffuse neuroendocrine system. Neuroendocrine tumors (NETs) can arise throughout the body, including the lungs…”
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Abstract 2001: Inhibiting voltage-gated sodium channel activity in medullary thyroid cancer using small molecule compounds by Ahuja, Paras, Guenter, Rachael, Cowan, Jaden, Shihab, Yazen, Whitt, Jason, Chen, Herbert, Velu, Sadanandan, Jaskula-Sztul, Renata

“…Medullary thyroid cancer (MTC) is a type of neuroendocrine cancer (NE) with increasing incidence worldwide. Compared with well-differentiated thyroid cancers,…”
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Overexpression of somatostatin receptor type 2 (SSTR2) in neuroendocrine tumors for improved [68Ga]DOTATATE imaging and treatment by Guenter, Rachael, Aweda, Tolulope, Carmona Matos, Danilea M., Jang, Samuel, Whitt, Jason, Cheng, Yi-Qiang, Liu, X. Margaret, Chen, Herbert, Lapi, Suzanne, Jaskula-Sztul, Renata

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Somatostatin Receptor Type 2 and Thyroid-Stimulating Hormone Receptor Expression in Oncocytic Thyroid Neoplasms: Implications for Prognosis and Treatment by Gillis, Andrea, Zheng-Pywell, Rui, McLeod, Chandler, Wang, Dezhi, Ness, John M., Guenter, Rachael, Whitt, Jason, Prolla, Tomas A., Chen, Herbert, Gonzalez, Manuel Lora, Rose, Bart, Lloyd, Ricardo V., Jaskula-Sztul, Renata, Lin, Diana

“…Somatostatin receptor type 2 (SSTR2) and thyroid-stimulating hormone receptor (TSHR) display variable expression in primary thyroid tumors and have been…”
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Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment by Guenter, Rachael, Aweda, Tolulope, Carmona Matos, Danilea M., Jang, Samuel, Whitt, Jason, Cheng, Yi-Qiang, Liu, X. Margaret, Chen, Herbert, Lapi, Suzanne E., Jaskula-Sztul, Renata

“…Neuroendocrine tumors are found throughout the body, including the pancreas. These tumors are phenotypically and genetically heterogeneous and can be difficult…”
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Thyroid-stimulating hormone receptor (TSHR) as a target for imaging differentiated thyroid cancer by Gimblet, Grayson R, Whitt, Jason, Houson, Hailey A, Lin, Diana, Guenter, Rachael, Rao, Tejeshwar C, Wang, Dezhi, Ness, John, Gonzalez, Manuel Lora, Murphy, Madisen S, Gillis, Andrea, Chen, Herbert, Copland, John A, Kenderian, Saad S, Lloyd, Ricardo V, Szkudlinski, Mariusz W, Lapi, Suzanne E, Jaskula-Sztul, Renata

“…Of the half a million cases of thyroid cancer diagnosed annually, 95% are differentiated thyroid cancers. Although clinical guidelines recommend surgical…”
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A growth model of neuroendocrine tumor surrogates and the efficacy of a novel somatostatin-receptor–guided antibody-drug conjugate: Perspectives on clinical response? by Herring, Brendon, Whitt, Jason, Aweda, Tolulope, Ou, Jianfa, Guenter, Rachael, Lapi, Suzanne, Berry, Joel, Chen, Herbert, Liu, Xiaoguang, Rose, J. Bart, Jaskula-Sztul, Renata

“…As patient-derived xenografts and other preclinical models of neuroendocrine tumors for testing personalized therapeutics are lacking, we have developed a…”
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Abstract 4463: Metabolic reprogramming through Notch1 signaling promotes a survival advantage in pancreatic neuroendocrine tumor cells by Guenter, Rachael, Chen, Weisheng, Herring, Brendon, Golivi, Yuvasri, Sammy, Melissa, Whitt, Jason, Jaskula-Sztul, Renata, Chen, Herbert, Rose, J. Bart

“…Background: Cancer cells utilize both oxidative phosphorylation (OXPHOS) and glycolysis to generate energy. Switching between OXPHOS and glycolysis can promote…”
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Abstract 4387: Interplay of Notch1 and Notch3 signaling regulates pancreatic neuroendocrine tumor proliferation by Guenter, Rachael, Chen, Weisheng, Golivi, Yuvasri, Robledo, Mario, Adams, Cole, Jaskula-Sztul, Renata, Chen, Herbert, Rose, J. Bart

“…Background: The 5-year survival rate for patients with advanced pancreatic neuroendocrine tumors (pNETs) is less than 30%. Notch signaling is a transmembrane…”
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Abstract PR002: Transcriptomic influences of racial disparities in Black patients with pancreatic neuroendocrine tumors by Herring, Brendon, Guenter, Rachael, Dhall, Deepti, Chen, Herbert, Yates, Clayton, Rose, John Bart

“…Introduction: There are known disparities in outcomes between Black and White patients with pancreatic neuroendocrine tumors (pNETs). Recently, Black patients…”
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Voltage-Gated Sodium Channel NaV1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells by Pukkanasut, Piyasuda, Whitt, Jason, Guenter, Rachael, Lynch, Shannon E., Gallegos, Carlos, Rosendo-Pineda, Margarita Jacaranda, Gomora, Juan Carlos, Chen, Herbert, Lin, Diana, Sorace, Anna, Jaskula-Sztul, Renata, Velu, Sadanandan E.

“…Our results from quantitative RT-PCR, Western blotting, immunohistochemistry, and the tissue microarray of medullary thyroid cancer (MTC) cell lines and…”
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Voltage-Gated Sodium Channel Na V 1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells by Pukkanasut, Piyasuda, Whitt, Jason, Guenter, Rachael, Lynch, Shannon E, Gallegos, Carlos, Rosendo-Pineda, Margarita Jacaranda, Gomora, Juan Carlos, Chen, Herbert, Lin, Diana, Sorace, Anna, Jaskula-Sztul, Renata, Velu, Sadanandan E

“…Our results from quantitative RT-PCR, Western blotting, immunohistochemistry, and the tissue microarray of medullary thyroid cancer (MTC) cell lines and…”
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