Search Results - "Guenduez, Dursun"

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    Cardiac Troponin I: A Valuable Biomarker Indicating the Cardiac Involvement in Fabry Disease by Tanislav, Christian, Guenduez, Dursun, Liebetrau, Christoph, Giese, Anne Kathrin, Eichler, Sabrina, Sieweke, Nicole, Speth, Maria, Bauer, Timm, Hamm, Christian, Rolfs, Arndt

    Published in PloS one (20-06-2016)
    “…Assessment of the clinical severity of Fabry disease (FD), an X-linked, rare, progressive disorder based on a genetic defect in alpha-galactosidase is…”
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    Journal Article
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    Fibrinogen Promotes Early Atherosclerotic Changes of the Carotid Artery in Young, Healthy Adults by Grebe, Mathias T, Luu, Brigitte, Sedding, Daniel, Heidt, Martin Clemens, Kemkes-Matthes, Bettina, Schaefer, Christian Alexander, Tillmanns, Harald H, Gündüz, Dursun

    Published in Journal of Atherosclerosis and Thrombosis (01-01-2010)
    “…Aim: To determine whether high plasma levels or activities of different hemostatic proteins contribute to the development of early atherosclerotic vessel wall…”
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    Inhibition of Cx43 attenuates ERK1/2 activation, enhances the expression of Cav‑1 and suppresses cell proliferation by Arshad, Muhammad, Conzelmann, Charlotte, Riaz, Muhammad Assad, Noll, Thomas, Gündüz, Dursun

    “…In addition to being an important component of the gap junction, connexin 43 (Cx43) has been shown to regulate other cellular functions, including cell…”
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    Compound C inhibits in vitro angiogenesis and ameliorates thrombin-induced endothelial barrier failure by Gündüz, Dursun, Klewer, Matthias, Bauer, Pascal, Tanislav, Christian, Sedding, Daniel, Rohrbach, Susanne, Schulz, Rainer, Aslam, Muhammad

    Published in European journal of pharmacology (05-12-2015)
    “…Compound C (comp. C) is a cell-permeable pyrrazolopyrimidine derivative and widely used as adenosine monophosphate-activated protein kinase (AMPK) inhibitor to…”
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    Effect of ticagrelor on endothelial calcium signalling and barrier function by Gündüz, Dursun, Tanislav, Christian, Schlüter, Klaus-Dieter, Schulz, Rainer, Hamm, Christian, Aslam, Muhammad

    Published in Thrombosis and haemostasis (26-01-2017)
    “…The P2Y receptor is a G -coupled receptor whose activation inhibits adenylyl cyclase and thereby reduces the concentration of intracellular cAMP. Here the…”
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    Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function by Aslam, Muhammad, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Gündüz, Dursun, Hamm, Christian W

    “…The members of Rho family of GTPases, RhoA and Rac1 regulate endothelial cytoskeleton dynamics and hence barrier integrity. The spatial activities of these…”
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    Hypoxia–reoxygenation‐induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase by Aslam, Muhammad, Schluter, Klaus‐Dieter, Rohrbach, Susanne, Rafiq, Amir, Nazli, Sabiha, Piper, Hans Michael, Noll, Thomas, Schulz, Rainer, Gündüz, Dursun

    Published in The Journal of physiology (01-01-2013)
    “…Key points •  Hypoxia–reoxygenation induces loss of endothelial barrier function and oedema formation accompanied by a rise in intracellular Ca2+, an increase…”
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    cAMP/PKA antagonizes thrombin-induced inactivation of endothelial myosin light chain phosphatase: role of CPI-17 by Aslam, Muhammad, Härtel, Frauke V., Arshad, Muhammad, Gündüz, Dursun, Abdallah, Yaser, Sauer, Heinrich, Piper, Hans Michael, Noll, Thomas

    Published in Cardiovascular research (15-07-2010)
    “…Aims Activation of cAMP signalling abrogates thrombin-induced hyperpermeability. One of the mechanisms underlying this protective effect is the inactivation of…”
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    Simultaneous Isolation of High Quality Cardiomyocytes, Endothelial Cells, and Fibroblasts from an Adult Rat Heart by Gündüz, Dursun, Hamm, Christian W, Aslam, Muhammad

    Published in Journal of visualized experiments (19-05-2017)
    “…The rat is an important animal model used in cardiovascular research, and rat cardiac cells are used routinely for in vitro analysis of the molecular…”
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    Continuous cardiac troponin I release in Fabry disease by Feustel, Andreas, Hahn, Andreas, Schneider, Christian, Sieweke, Nicole, Franzen, Wolfgang, Gündüz, Dursun, Rolfs, Arndt, Tanislav, Christian

    Published in PloS one (13-03-2014)
    “…Fabry disease (FD) is a rare lysosomal storage disorder also affecting the heart. The aims of this study were to determine the frequency of cardiac troponin I…”
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    cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation by Aslam, Muhammad, Tanislav, Christian, Troidl, Christian, Schulz, Rainer, Hamm, Christian, Gündüz, Dursun

    Published in Physiological reports (01-10-2014)
    “…Inflammatory mediators like thrombin disrupt endothelial adherens junctions (AJs) and barrier integrity leading to oedema formation followed by resealing of…”
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