Search Results - "Guehennec, Jérémy"

ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma by Dréan, Antonin, Rosenberg, Shai, Lejeune, François-Xavier, Goli, Larissa, Nadaradjane, Aravindan Arun, Guehennec, Jérémy, Schmitt, Charlotte, Verreault, Maïté, Bielle, Franck, Mokhtari, Karima, Sanson, Marc, Carpentier, Alexandre, Delattre, Jean-Yves, Idbaih, Ahmed

“…ATP-binding cassette transporters (ABC transporters) regulate traffic of multiple compounds, including chemotherapeutic agents, through biological membranes…”
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Temporary blood–brain barrier disruption by low intensity pulsed ultrasound increases carboplatin delivery and efficacy in preclinical models of glioblastoma by Dréan, Antonin, Lemaire, Nolwenn, Bouchoux, Guillaume, Goldwirt, Lauriane, Canney, Michael, Goli, Larissa, Bouzidi, Amira, Schmitt, Charlotte, Guehennec, Jeremy, Verreault, Maïté, Sanson, Marc, Delattre, Jean-Yves, Mokhtari, Karima, Sottilini, Frédéric, Carpentier, Alexandre, Idbaih, Ahmed

“…Introduction Glioblastoma (GBM) is the most common and aggressive primary brain cancer in adults. Few cytotoxic chemotherapies have been shown to be effective…”
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Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas by Verreault, Maite, Schmitt, Charlotte, Goldwirt, Lauriane, Pelton, Kristine, Haidar, Samer, Levasseur, Camille, Guehennec, Jeremy, Knoff, David, Labussière, Marianne, Marie, Yannick, Ligon, Azra H, Mokhtari, Karima, Hoang-Xuan, Khê, Sanson, Marc, Alexander, Brian M, Wen, Patrick Y, Delattre, Jean-Yves, Ligon, Keith L, Idbaih, Ahmed

“…p53 pathway alterations are key molecular events in glioblastoma (GBM). MDM2 inhibitors increase expression and stability of p53 and are presumed to be most…”
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Blood-brain barrier, cytotoxic chemotherapies and glioblastoma by Dréan, Antonin, Goldwirt, Lauriane, Verreault, Maïté, Canney, Michael, Schmitt, Charlotte, Guehennec, Jeremy, Delattre, Jean-Yves, Carpentier, Alexandre, Idbaih, Ahmed

“…Glioblastomas (GBM) are the most common and aggressive primary malignant brain tumors in adults. The blood brain barrier (BBB) is a major limitation reducing…”
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Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors by Rosenberg, Shai, Verreault, Maïté, Schmitt, Charlotte, Guegan, Justine, Guehennec, Jeremy, Levasseur, Camille, Marie, Yannick, Bielle, Franck, Mokhtari, Karima, Hoang-Xuan, Khê, Ligon, Keith, Sanson, Marc, Delattre, Jean-Yves, Idbaih, Ahmed

“…Glioblastoma (GBM) is the deadliest primary brain cancer in adults. Emerging innovative therapies hold promise for personalized cancer treatment. Improving…”
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Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma by Verreault, Maïté, Segoviano Vilchis, Irma, Rosenberg, Shai, Lemaire, Nolwenn, Schmitt, Charlotte, Guehennec, Jérémy, Royer‐Perron, Louis, Thomas, Jean‐Léon, Lam, TuKiet T., Dingli, Florent, Loew, Damarys, Ducray, François, Paris, Sophie, Carpentier, Catherine, Marie, Yannick, Laigle‐Donadey, Florence, Rousseau, Audrey, Pigat, Natascha, Boutillon, Florence, Bielle, Franck, Mokhtari, Karima, Frank, Stuart J., Reyniès, Aurélien, Hoang‐Xuan, Khê, Sanson, Marc, Goffin, Vincent, Idbaih, Ahmed

“…Objective New therapeutic approaches are needed to improve the prognosis of glioblastoma (GBM) patients. Methods With the objective of identifying alternative…”
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Correction to: ATP binding cassette (ABC) transporters: expression and clinical value in glioblastoma by Dréan, Antonin, Rosenberg, Shai, Lejeune, François-Xavier, Goli, Larissa, Nadaradjane, Aravindan Arun, Guehennec, Jérémy, Schmitt, Charlotte, Verreault, Maïté, Bielle, Franck, Mokhtari, Karima, Sanson, Marc, Carpentier, Alexandre, Delattre, Jean-Yves, Idbaih, Ahmed

“…The names of authors Marc Sanson and Jean-Yves Delattre were incorrectly presented in the initial online publication. The original article has been corrected…”
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EXTH-59. IDENTIFICATION OF GROWTH HORMONE RECEPTOR AS A RELEVANT TARGET FOR PRECISION MEDICINE IN LOW-EGFR EXPRESSING GLIOBLASTOMA by Verreault, Maite, Vilchis, Irma Segoviano, Rosenberg, Shai, Lemaire, Nolwenn, Schmitt, Charlotte, Guehennec, Jeremy, Royer-Perron, Louis, Thomas, Jean-Leon, Lam, Tukiet T, Dingli, Florent, Loew, Damarys, Ducray, Francois, Paris, Sophie, Carpentier, Catherine, Marie, Yannick, Laigle-Donadey, Florence, Rousseau, Audrey, Pigat, Natascha, Boutillon, Florence, Bielle, Franck, Mokhtari, Karima, Frank, Stuart J, de Reynies, Aurelien, Hoang-Xuan, Khe, Sanson, Marc, Goffin, Vincent, Idbaih, Ahmed

“…New therapeutic approaches are needed to improve the prognosis of Glioblastoma (GBM) patients. With the objective of identifying alternative oncogenic…”
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Brain distribution of the MDM2 inhibitor, RG7112: Single dose escalation and repeated doses studies by Goldwirt, Lauriane, Verreault, Maite, Levasseur, Camille, Schmitt, Charlotte, Guehennec, Jeremy, Labussiere, Marianne, Haidar, Sam, Mokhtari, Karima, Mourah, Samia, Hoang-Xuan, Khe, Sanson, Marc, Wen, Patrick Y., Ligon, Keith L., Delattre, Jean-Yves, Idbaih, Ahmed

“…Abstract only…”
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ET-62HIGHLY SELECTIVE ACTIVITY OF MDM2 INHIBITOR RG7112 AGAINST MDM2-AMPLIFIED/TP53 WILD-TYPE GLIOBLASTOMAS by Verreault, Maite, Levasseur, Camille, Schmitt, Charlotte, Guehennec, Jeremy, Labussiere, Marianne, Marie, Yannick, Haidar, Sam, Mokhtari, Karima, Hoang-Xuan, Khe, Sanson, Marc, Ligon, Keith, Delattre, Jean-Yves, Idbaih, Ahmed

“…Alteration of P53 pathway is one of the key molecular events involved in glioblastoma (GBM) biology. Genetic alterations which reduce TP53 function in GBM…”
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ET-62 HIGHLY SELECTIVE ACTIVITY OF MDM2 INHIBITOR RG7112 AGAINST MDM2-AMPLIFIED/TP53 WILD-TYPE GLIOBLASTOMAS by Verreault, M., Levasseur, C., Schmitt, C., Guehennec, J., Labussiere, M., Marie, Y., Haidar, S., Mokhtari, K., Hoang-Xuan, K., Sanson, M., Ligon, K., Delattre, J.-Y., Idbaih, A.

“…Alteration of P53 pathway is one of the key molecular events involved in glioblastoma (GBM) biology. Genetic alterations which reduce TP53 function in GBM…”
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GENO-33PATIENT DERIVED GLIOBLASTOMA CELL LINES RECAPITULATE PARENTAL TUMORS' MOLECULAR LANDSCAPE by Rosenberg, Shai, Verreault, Maité, Schmitt, Charlotte, Guegan, Justine, Guehennec, Jeremy, Levasseur, Camille, Marie, Yannick, Mokhtari, Karima, Hoang-Xuan, Khê, Sanson, Marc, Delattre, Jean-Yves, Idbaih, Ahmed

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