Search Results - "Gueguen, Yann"

Review of Knowledge of Uranium-Induced Kidney Toxicity for the Development of an Adverse Outcome Pathway to Renal Impairment by Guéguen, Yann, Frerejacques, Marie

“…An adverse outcome pathway (AOP) is a conceptual construct of causally and sequentially linked events, which occur during exposure to stressors, with an…”
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Adaptive responses to low doses of radiation or chemicals: their cellular and molecular mechanisms by Guéguen, Yann, Bontemps, Alice, Ebrahimian, Teni G.

“…This article reviews the current knowledge on the mechanisms of adaptive response to low doses of ionizing radiation or chemical exposure. A better knowledge…”
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Fracture toughness, fracture energy and slow crack growth of glass as investigated by the Single-Edge Precracked Beam (SEPB) and Chevron-Notched Beam (CNB) methods by To, Theany, Célarié, Fabrice, Roux-Langlois, Clément, Bazin, Arnaud, Gueguen, Yann, Orain, Hervé, Le Fur, Mickaël, Burgaud, Vincent, Rouxel, Tanguy

“…We show that the Single-Edge Precracked Beam (SEPB) test is not only suitable to the determination of the fracture toughness (KIc) of glass, but also offers a…”
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Physical properties of the GexSe1−x glasses in the 0<x<0.42 range in correlation with their structure by Yang, Guang, Gueguen, Yann, Sangleboeuf, Jean-Christophe, Rouxel, Tanguy, Boussard-Plédel, Catherine, Troles, Johann, Lucas, Pierre, Bureau, Bruno

“…Physical properties, including mechanical, thermal and optical properties, have been investigated for chalcogenide glasses in the GexSe1−x system, for x…”
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Evidence and modeling of mechanoluminescence in a transparent glass particulate composite by Dubernet, Marion, Gueguen, Yann, Houizot, Patrick, Célarié, Fabrice, Sangleboeuf, Jean-Christophe, Orain, Hervé, Rouxel, Tanguy

“…Mechanoluminescence (ML) of a transparent alkali-phosphate glass composite with SrAl2O4:Eu, Dy particles is reported. Uniaxial compression experiments show the…”
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Renal adaptive response to exposure to low doses of uranyl nitrate and sodium fluoride in mice by Bontemps-Karcher, Alice, Magneron, Victor, Conquet, Laurine, Elie, Christelle, Gloaguen, Céline, Kereselidze, Dimitri, Roy, Laurence, Barbier, Olivier C., Guéguen, Yann

“…[Display omitted] •Uranium and fluoride induce an adaptive response in mice exposed chronically.•Apoptosis regulation is involved in uranium-induced adaptive…”
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Structure and viscosity of phase‐separated BaO–SiO2 glasses by Gueguen, Yann, Houizot, Patrick, Célarié, Fabrice, Chen, Mingwei, Hirata, Akihiko, Tan, Yongwen, Allix, Mathieu, Chenu, Sébastien, Roux‐Langlois, Clément, Rouxel, Tanguy

“…Barium silicate glasses with 0‐40 mol% BaO were synthesized either by aerodynamical levitation and laser heating (at low barium content) or by conventional…”
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Chronic Internal Exposure to Low Dose 137Cs Induces Positive Impact on the Stability of Atherosclerotic Plaques by Reducing Inflammation in ApoE-/- Mice by Le Gallic, Clélia, Phalente, Yohann, Manens, Line, Dublineau, Isabelle, Benderitter, Marc, Gueguen, Yann, Lehoux, Stephanie, Ebrahimian, Teni G

“…After Chernobyl and Fukushima Daï Chi, two major nuclear accidents, large amounts of radionuclides were released in the environment, mostly caesium 137…”
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Chronic exposure of adult, postnatal and in utero rat models to low-dose 137Cesium: impact on circulating biomarkers by Manens, Line, Grison, Stéphane, Bertho, Jean-Marc, Lestaevel, Philippe, Guéguen, Yann, Benderitter, Marc, Aigueperse, Jocelyne, Souidi, Maâmar

“…The presence of Cesium ( Cs) in the environment after nuclear accidents at Chernobyl and more recently Fukushima Daiichi raises many health issues for the…”
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Ionizing radiation biomarkers in epidemiological studies – An update by Hall, Janet, Jeggo, Penny A., West, Catharine, Gomolka, Maria, Quintens, Roel, Badie, Christophe, Laurent, Olivier, Aerts, An, Anastasov, Nataša, Azimzadeh, Omid, Azizova, Tamara, Baatout, Sarah, Baselet, Bjorn, Benotmane, Mohammed A., Blanchardon, Eric, Guéguen, Yann, Haghdoost, Siamak, Harms-Ringhdahl, Mats, Hess, Julia, Kreuzer, Michaela, Laurier, Dominique, Macaeva, Ellina, Manning, Grainne, Pernot, Eileen, Ravanat, Jean-Luc, Sabatier, Laure, Tack, Karine, Tapio, Soile, Zitzelsberger, Horst, Cardis, Elisabeth

“…Recent epidemiology studies highlighted the detrimental health effects of exposure to low dose and low dose rate ionizing radiation (IR): nuclear industry…”
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Modifications of the Expression of Genes Involved in Cerebral Cholesterol Metabolism in the Rat Following Chronic Ingestion of Depleted Uranium by Racine, Radjini, Gueguen, Yann, Gourmelon, Patrick, Veyssiere, Georges, Souidi, Maâmar

“…Depleted uranium results from the enrichment of natural uranium for energetic purpose. Its potential dispersion in the environment would set human populations…”
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Overview of Traditional and Environmental Factors Related to Bone Health by Rubio-Gutierrez, Juan Carlos, Mendez-Hernández, Pablo, Guéguen, Yann, Galichon, Pierre, Tamayo-Ortiz, Marcela, Haupt, Karsten, Medeiros, Mara, Barbier, Olivier Christophe

“…Bone mass in adulthood depends on growth and mineralization acquired during childhood and adolescence. It is well known that these stages of life are crucial…”
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Renal toxicity and biokinetics models after repeated uranium instillation by De Castro, Laurie, Manoury, Annabelle, Claude, Olivier, Simoneau, Bastien, Monceau, Virginie, Suhard, David, Elie, Christelle, Magneron, Victor, Roy, Laurence, Bouvier-Capely, Céline, Ibanez, Chrystelle, Davesne, Estelle, Guéguen, Yann

“…During nuclear fuel processing, workers can potentially be exposed to repeated inhalations of uranium compounds. Uranium nephrotoxicity is well documented…”
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In Vivo Comparison of the Phenotypic Aspects and Molecular Mechanisms of Two Nephrotoxic Agents, Sodium Fluoride and Uranyl Nitrate by Bontemps, Alice, Conquet, Laurine, Elie, Christelle, Magneron, Victor, Gloaguen, Céline, Kereselidze, Dimitri, Tack, Karine, Barbier, Olivier C, Guéguen, Yann

“…Because of their nephrotoxicity and presence in the environment, uranium (U) and fluoride (F) represent risks to the global population. There is a general lack…”
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Biomarkers for Uranium Risk Assessment for the Development of the CURE (Concerted Uranium Research in Europe) Molecular Epidemiological Protocol by Guéguen, Yann, Roy, Laurence, Hornhardt, Sabine, Badie, Christophe, Hall, Janet, Baatout, Sarah, Pernot, Eileen, Tomasek, Ladislav, Laurent, Olivier, Ebrahimian, Teni, Ibanez, Chrystelle, Grison, Stephane, Kabacik, Sylwia, Laurier, Dominique, Gomolka, Maria

“…Despite substantial experimental and epidemiological research, there is limited knowledge of the uranium-induce health effects after chronic low-dose exposures…”
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Al and Sr environment in tectosilicate glasses and melts: Viscosity, Raman and NMR investigation by Novikov, Alexey N., Neuville, Daniel R., Hennet, Louis, Gueguen, Yann, Thiaudière, Dominique, Charpentier, Thibault, Florian, Pierre

“…Structure and properties of SrO-Al2O3-SiO2 glasses and melts were investigated along the tectosilicate join (SrO/Al2O3=1), varying the amount of silica. The…”
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Vitamin D: metabolism, regulation and associated diseases by Tissandié, Emilie, Guéguen, Yann, Lobaccaro, Jean-Marc A, Aigueperse, Jocelyne, Souidi, Maâmar

“…Vitamin D is well known as a hormone involved in mineral metabolism and bone growth. Conversion into the active metabolite 1,25-dihydroxyvitamin D3…”
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In vivo animal studies help achieve international consensus on standards and guidelines for health risk estimates for chronic exposure to low levels of tritium in drinking water by Guéguen, Yann, Priest, Nicholas D., Dublineau, Isabelle, Bannister, Laura, Benderitter, Marc, Durand, Christelle, Ebrahimian, Teni G., Grégoire, Eric, Grison, Stéphane, Ibanez, Chrystelle, Legendre, Audrey, Lestaevel, Philippe, Roch‐Lefèvre, Sandrine, Roy, Laurence, Tack, Karine, Wyatt, Heather, Leblanc, Julie, Jourdain, Jean‐René, Klokov, Dmitry

“…Existing and future nuclear fusion technologies involve the production and use of large quantities of tritium, a highly volatile, but low toxicity…”
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Distribution of Soluble Uranium in the Nuclear Cell Compartment at Subtoxic Concentrations by Rouas, Caroline, Bensoussan, Helene, Suhard, David, Tessier, Christine, Grandcolas, Line, Rebiere, François, Dublineau, Isabelle, Taouis, Mohammed, Pallardy, Marc, Lestaevel, Philippe, Gueguen, Yann

“…Uranium is naturally found in the environment, and its extensive use results in an increased risk of human exposure. Kidney cells have mainly been used as in…”
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Low-concentration uranium enters the HepG2 cell nucleus rapidly and induces cell stress response by Guéguen, Yann, Suhard, David, Poisson, Clémentine, Manens, Line, Elie, Christelle, Landon, Géraldine, Bouvier-Capely, Céline, Rouas, Caroline, Benderitter, Marc, Tessier, Christine

“…This study aimed to compare the cell stress effects of low and high uranium concentrations and relate them to its localization, precipitate formation, and…”
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