Search Results - "Guedes, Simone"
-
1
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping
Published in PLoS neglected tropical diseases (02-04-2018)“…Infection with Trypanosoma cruzi causes Chagas disease, a major public health problem throughout Latin America. There is no vaccine and the only drugs have…”
Get full text
Journal Article -
2
H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion
Published in PLoS pathogens (01-02-2022)“…Histone variants play a crucial role in chromatin structure organization and gene expression. Trypanosomatids have an unusual H2B variant (H2B.V) that is known…”
Get full text
Journal Article -
3
Analysis of Aloe vera cytotoxicity and genotoxicity associated with endodontic medication and laser photobiomodulation
Published in Journal of photochemistry and photobiology. B, Biology (01-01-2018)“…This study aims to evaluate, in vitro, the effect of Aloe vera associated with endodontic medication, with or without laser photobiomodulation (FTL)…”
Get full text
Journal Article -
4
Identification of Novel Interspersed DNA Repetitive Elements in the Trypanosoma cruzi Genome Associated with the 3′UTRs of Surface Multigenic Families
Published in Genes (21-10-2020)“…Trypanosoma cruzi is the etiological agent of Chagas disease, which affects millions of people in Latin America. No transcriptional control of gene expression…”
Get full text
Journal Article -
5
Spindle cell carcinoma of the tongue: a case report in a young patient
Published in Bioscience journal (01-05-2017)“…Spindle cell carcinoma (SpCC) is a rare biphasic tumor of epithelial origin that comprises squamous and sarcomatoid components. The diagnosis may be…”
Get full text
Journal Article -
6
Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery
Published in Nucleus (Austin, Tex.) (01-03-2011)“…In eukaryotes, many nuclear processes are spatially compartmentalized. Previously, we have shown that in Trypanosoma cruzi, an early-divergent eukaryote, DNA…”
Get full text
Journal Article -
7
Trypanosome Prereplication Machinery: A Potential New Target for an Old Problem
Published in Enzyme Research (2011)“…Approximately ten million people suffer from Chagas disease worldwide, caused by Trypanosoma cruzi, with the disease burden predominately focused in Latin…”
Get full text
Journal Article -
8
GESTÃO DE PESSOAS POR COMPETÊNCIAS: AVALIAÇÃO DE UM MODELO IMPLEMENTADO NUMA ORGANIZAÇÃO DO SETOR PETROQUÍMICO
Published in Revista de Carreiras e Pessoas (27-04-2012)“…Este artigo propõe-se a estudar o caso de uma empresa brasileira do setor petroquímico, que implementou um modelo de gestão por competências no ano de 2001. O…”
Get full text
Journal Article -
9
Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the Trypanosoma cruzi Life Cycle and Blocks Parasite Infectivity
Published in Antimicrobial agents and chemotherapy (01-05-2019)“…Pep5 (WELVVLGKL) is a fragment of cyclin D2 that exhibits a 2-fold increase in the S phase of the HeLa cell cycle. When covalently bound to a cell-penetrating…”
Get full text
Journal Article -
10
Single molecule analysis of Trypanosoma brucei DNA replication dynamics
Published in Nucleic acids research (11-03-2015)“…Eukaryotic genome duplication relies on origins of replication, distributed over multiple chromosomes, to initiate DNA replication. A recent genome-wide…”
Get full text
Journal Article -
11
Quantitative Proteomic Analysis of Replicative and Nonreplicative Forms Reveals Important Insights into Chromatin Biology of Trypanosoma cruzi
Published in Molecular & cellular proteomics (01-01-2017)“…Chromatin associated proteins are key regulators of many important processes in the cell. Trypanosoma cruzi, a protozoa flagellate that causes Chagas disease,…”
Get full text
Journal Article -
12
Identification of Novel Interspersed DNA Repetitive Elements in the Trypanosoma cruzi Genome Associated with the 3'UTRs of Surface Multigenic Families
Published in Genes (21-10-2020)“…Trypanosoma cruzi is the etiological agent of Chagas disease, which affects millions of people in Latin America. No transcriptional control of gene expression…”
Get full text
Journal Article -
13
Cultura tecnológica e vulnerabilidade ao trauma psíquico
Published in Mundo da saúde (1995) (01-04-2012)“…O desenvolvimento das tecnologias de informação e comunicação (TIC), nas últimas décadas, repercutiu de maneira intensa em muitos aspectos da vida social e…”
Get full text
Journal Article -
14
Cultura tecnológica e vulnerabilidade ao trauma psíquico
Published in Mundo da saúde (1995) (30-06-2012)Get full text
Journal Article -
15
Análise da satisfação dos profissionais de saúde da família com as condições de trabalho DOI: 10.4025/cienccuidsaude.v12i1.17135
Published in Ciência, cuidado e saúde (09-10-2013)Get full text
Journal Article -
16
Relação entre qualidade de vida no trabalho e indicadores de satisfação profissional
Published 01-01-2009“…O presente estudo enquadra-se no âmbito de um projecto de investigação sobre a Qualidade de Vida no Trabalho (QVT) que, entre outros aspectos, visa o…”
Get full text
Dissertation -
17
Direitos Individuais e Coletivos da Pessoa Portadora de Doença Crónica
Published 01-01-2019“…A doença crónica é incurável e está cada vez mais presente nas pessoas da nossa sociedade. Por isso, esta tem que estar preparada para dar resposta às…”
Get full text
Dissertation -
18
Spindle cell carcinoma of the tongue: a case report in a young patient
Published in Bioscience journal (01-05-2017)“…Spindle cell carcinoma (SpCC) is a rare biphasic tumor of epithelial origin that comprises squamous and sarcomatoid components. The diagnosis may be…”
Get full text
Journal Article -
19
Perfil dos atendimentos psiquiátricos realizados pelo Serviço de Atendimento Móvel de Urgência, Aracaju, janeiro/2010 a fevereiro/2011
Published in Interfaces científicas : saúde e ambiente (29-09-2012)“…A Política Nacional de Urgência e Emergência garante atenção integral ao atendimento das urgências clínicas, cirúrgicas, gineco-obstétricas, psiquiátricas,…”
Get full text
Journal Article -
20
Mortality from oral cancer in Aracaju/SE, Brazil: 2000-2009
Published in Revista de Odontologia da UNESP“…INTRODUCTION: The incidence of oral cancer varies widely in the world, with two thirds of cases diagnosed in developing countries. OBJECTIVE: To investigate…”
Get full text
Journal Article