Search Results - "Guedes, Leonor"

Are genetic and idiopathic forms of Parkinson's disease the same disease? by Correia Guedes, Leonor, Mestre, Tiago, Outeiro, Tiago F., Ferreira, Joaquim J.

“…Genetic forms represent a small fraction of Parkinson's disease (PD) but their discovery has revolutionized research in the field, putting α‐synuclein in the…”
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Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease by Martins, Madalena, Rosa, Alexandra, Guedes, Leonor C, Fonseca, Benedita V, Gotovac, Kristina, Violante, Sara, Mestre, Tiago, Coelho, Miguel, Rosa, Mário M, Martin, Eden R, Vance, Jeffery M, Outeiro, Tiago F, Wang, Liyong, Borovecki, Fran, Ferreira, Joaquim J, Oliveira, Sofia A

“…miRNAs were recently implicated in the pathogenesis of numerous diseases, including neurological disorders such as Parkinson's disease (PD). miRNAs are…”
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Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson’s disease by Vicente Miranda, Hugo, Cassio, Rafaela, Correia Guedes, Leonor, Gomes, Marcos António, Chegão, Ana, Miranda, Elisa, Soares, Tiago, Coelho, Miguel, COELHO DA SILVA ROSA, MÁRIO MIGUEL, Ferreira, Joaquim J, Outeiro, Tiago

“…© The Author(s) 2017. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Upper motor neuron signs in primary lateral sclerosis and hereditary spastic paraplegia by Santos Silva, Cláudia, Correia Rodrigues, Catarina, Fortuna Baptista, Maria, Oliveira Santos, Miguel, Gromicho, Marta, Carvalho, Vanessa, Correia Guedes, Leonor, Carvalho, Mamede

“…Introduction/Aims The frequency and distribution of upper motor neuron (UMN) signs in primary lateral sclerosis (PLS) are unknown. We aimed to study the…”
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Survival, mortality, causes and places of death in a european Huntington's disease prospective cohort by Rodrigues, Filipe Brogueira, abreu, daisy, Damásio, Joana, Cabral Gonçalves, Nilza Karina, Correia Guedes, Leonor, Coelho, Miguel, Ferreira, Joaquim J

“…© 2017 International Parkinson and Movement Disorder Society Background: Huntington's disease (HD) is a rare and fatal inherited genetic disorder characterized…”
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Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles by Pinho, Raquel, Guedes, Leonor C, Soreq, Lilach, Lobo, Patrícia P, Mestre, Tiago, Coelho, Miguel, Rosa, Mário M, Gonçalves, Nilza, Wales, Pauline, Mendes, Tiago, Gerhardt, Ellen, Fahlbusch, Christiane, Bonifati, Vincenzo, Bonin, Michael, Miltenberger-Miltényi, Gabriel, Borovecki, Fran, Soreq, Hermona, Ferreira, Joaquim J, F Outeiro, Tiago

“…The prognosis of neurodegenerative disorders is clinically challenging due to the inexistence of established biomarkers for predicting disease progression…”
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Substantia nigra neuromelanin-MR imaging differentiates essential tremor from Parkinson's disease by Reimão, Sofia, Pita Lobo, Patrícia, Neutel, Dulce, Guedes, Leonor Correia, Coelho, Miguel, Rosa, Mário M., Azevedo, Pedro, Ferreira, Joana, Abreu, Daisy, Gonçalves, Nilza, Nunes, Rita G., Campos, Jorge, Ferreira, Joaquim J.

“…© 2015 International Parkinson and Movement Disorder Society Background: Essential tremor (ET) is a very common movement disorder that has no diagnostic…”
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Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study by Reilmann, Ralf, Anderson, Karen E, Feigin, Andrew, Tabrizi, Sarah J, Leavitt, Blair R, Stout, Julie C, Piccini, Paola, Schubert, Robin, Loupe, Pippa, Wickenberg, Anna, Borowsky, Beth, Rynkowski, Gail, Volkinshtein, Rita, Li, Thomas, Savola, Juha-Matti, Hayden, Michael, Gordon, Mark Forrest, Guttman, Mark, Raymond, Lynn, Mendis, Tilak, Suchowersky, Oksana, Corey-Bloom, Jody, Geschwind, Michael D, Marshall, Frederick J, Marder, Karen S, Nance, Martha, Racette, Brad, Bang, Jee, Segro, Victoria, McDonell, Katherine, Kamholz, John, LeDoux, Mark S, Sanchez-Ramos, Juan, DeMichele, Giuseppe, Mariotti, Caterina, Squitieri, Ferdinando, Soliveri, Paola, Cortelli, Pietro, Muñoz García, José Esteban, Kulisevsky Bojarski, Jaime, López-Sendón Moreno, José Luis, Berganzo Corrales, Koldo, Cubo, Esther, García Moreno, José Manuel, Orth, Michael, Priller, Josef, Saft, Carsten, Weindl, Adolf, Winkler, Juergen, Craufurd, David, Miedzybrodzka, Zofia, Rickards, Hugh, Davies, Rhys Richard, Lahiri, Nayana, Ruddy, Deborah, Komati, Suresh K, Quarrell, Oliver William John, Correira Guedes, Leonor, Roos, Raymund A C, Zalyalova, Zuleykha, Illarioshkin, Sergey, Gustov, Aleksandr, Klempir, Jiri

“…Laquinimod modulates CNS inflammatory pathways thought to be involved in the pathology of Huntington's disease. Studies with laquinimod in transgenic rodent…”
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Circulating Inflammatory miRNAs Associated with Parkinson's Disease Pathophysiology by Oliveira, Sara R, Dionísio, Pedro A, Correia Guedes, Leonor, Gonçalves, Nilza, Coelho, Miguel, Rosa, Mário M, Amaral, Joana D, Ferreira, Joaquim J, Rodrigues, Cecília M P

“…Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide, being largely characterized by motor features. MicroRNAs (miRNAs) are…”
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Tremor and Parkinsonism in chromosomopathies : a systematic review by Carvalho, Vanessa, Ferreira, Joaquim J, Correia Guedes, Leonor

“…© 2021 International Parkinson and Movement Disorder Society The landscape of genetic forms of Parkinson's diseases (PD) has grown exponentially in recent…”
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HSD10 disease in a female patient with juvenile onset parkinsonism by Rosário, Madalena, Carvalho, Vanessa, Moldovan, Oana, Crawford, Joana, Chendo, Inês, Reimão, Sofia, Rosa, Mário Miguel, Correia Guedes, Leonor

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A distinct neuromelanin magnetic resonance imaging pattern in parkinsonian multiple system atrophy by Simões, Rita Moiron, Castro Caldas, Ana, Grilo, Joana, Correia, Daisy, Leão Guerreiro, Carla, Pita Lobo, Patrícia, Valadas, Anabela, Fabbri, Marguerita, Correia Guedes, Leonor, Coelho, Miguel, COELHO DA SILVA ROSA, MÁRIO MIGUEL, Ferreira, Joaquim J, Reimão, Sofia

“…© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Do patients with late-stage Parkinson’s disease still respond to levodopa? by Fabbri, Margherita, MD, Coelho, Miguel, MD, Abreu, Daisy, Guedes, Leonor Correia, MD, Rosa, Mario M., MD, Costa, Nilza, Antonini, Angelo, MD, PhD, Ferreira, Joaquim J., MD, PhD

“…Abstract Background Late-stage Parkinson’ disease (PD) is dominated by loss of autonomy due to motor and non-motor symptoms which can be marginally corrected…”
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Correction: Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles by Pinho, Raquel, Guedes, Leonor C, Soreq, Lilach, Lobo, Patrícia P, Mestre, Tiago, Coelho, Miguel, Rosa, Mário M, Gonçalves, Nilza, Wales, Pauline, Mendes, Tiago, Gerhardt, Ellen, Fahlbusch, Christiane, Bonifati, Vincenzo, Bonin, Michael, Miltenberger-Miltényi, Gabriel, Borovecki, Fran, Soreq, Hermona, Ferreira, Joaquim J, Outeiro, Tiago F

“…[This corrects the article DOI: 10.1371/journal.pone.0157852.]…”
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Acute response of non-motor symptoms to subthalamic deep brain stimulation in Parkinson's disease by Fabbri, Margherita, MD, Coelho, Miguel, MD, PhD, Guedes, Leonor Correia, MD, Rosa, Mario M., MD, PhD, Abreu, Daisy, MsC, Gonçalves, Nilza, MsC, Antonini, Angelo, MD, PhD, Ferreira, Joaquim J., MD, PhD

“…Abstract Background Subthalamic deep brain stimulation (STN-DBS) is an established treatment for the motor complications of Parkinson's disease (PD) and may…”
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Clinical trials in palliative care : a systematic review of their methodological characteristics and of the quality of their reporting by Bouça-Machado, Raquel, Rosário, Madalena, Alarcão, Joana, Correia Guedes, Leonor, abreu, daisy, Ferreira, Joaquim J

“…© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License…”
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3D Kinematics Quantifies Gait Response to Levodopa earlier and to a more Comprehensive Extent than the MDS‐Unified Parkinson's Disease Rating Scale in Patients with Motor Complications by Barbosa, Raquel, Mendonça, Marcelo, Bastos, Paulo, Pita Lobo, Patrícia, Valadas, Anabela, Correia Guedes, Leonor, Ferreira, Joaquim J., Rosa, Mário Miguel, Matias, Ricardo, Coelho, Miguel

“…Background Quantitative 3D movement analysis using inertial measurement units (IMUs) allows for a more detailed characterization of motor patterns than…”
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Molecular characterization of Portuguese patients with hereditary cerebellar ataxia by Santos, Mariana, Damásio, Joana, Carmona, Susana, Aguiar Martins Neto, João Luís, Dehghani, Nadia, Correia Guedes, Leonor, Barbot, Clara, Barros, José, Brás, José, Sequeiros, Jorge, Guerreiro, Rita

“…© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative…”
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Patients and health professional's perspective of functional mobility in Parkinson's Disease by Bouça-Machado, Raquel, Cabral Gonçalves, Nilza Karina, Lousada, Inês, Patriarca, Maria A., Costa, Patrícia, Nunes, Raquel, Dias, Susana, Caldas, Ana Castro, Valadas, Anabela, Lobo, Patrícia Pita, Correia Guedes, Leonor, COELHO DA SILVA ROSA, MÁRIO MIGUEL, Coelho, Miguel, Ferreira, Joaquim J

“…Copyright © 2020 Bouça-Machado, Gonçalves, Lousada, Patriarca, Costa, Nunes, Dias, Caldas, Valadas, Lobo, Guedes, Rosa, Coelho and Ferreira. This is an…”
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Don’t Disregard Deep Brain Stimulation in Patients with Concomitant Gaucher and Parkinson Disease by Seabra, Mafalda, Lopes, Carolina, Costa, Manuela, Guedes, Leonor, Rosas, Maria

“…Gaucher disease and Parkinson’s disease can co-occur, and mutations in the glucocerebrosidase (GBA) gene are considered the most common genetic association…”
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