Search Results - "Gudyrev, O S"
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Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment
Published in Journal of osteoporosis (01-01-2018)“…The experiment was carried out on 120 female white Wistar rats, to study the endothelio- and osteoprotective action of the combination of rosuvastatin with…”
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Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background
Published in Journal of osteoporosis (01-01-2013)“…In the experiment on the white Wistar female rats (222 animals), the osteoprotective effect of enalapril and losartan was studied on experimental models of…”
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APPswe/PS1dE9/Blg Transgenic Mouse Line for Modeling Cerebral Amyloid Angiopathy Associated with Alzheimer's Disease
Published in Molekuliarnaia biologiia (01-01-2023)“…Alzheimer's disease (AD) is the most common proteinopathy, which is accompanied by a steady decrease in the patient's cognitive functions with a simultaneous…”
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APPswe/PS1dE9/Blg Transgenic Mouse Line for Modeling Cerebral Amyloid Angiopathy Associated with Alzheimer’s Disease
Published in Molecular biology (New York) (01-02-2023)“…Alzheimer’s disease (AD) is the most common proteinopathy, which is accompanied by a steady decrease in the patient’s cognitive functions with a simultaneous…”
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Study of Endothelial Protective Activity of Phenol-Derived Thrombin and Arginase-2 Inhibitors KUD-259 and KUD-974
Published in Bulletin of experimental biology and medicine (01-08-2017)“…We performed correction of endothelial dysfunction with phenol derivatives KUD-259 and KUD-974 containing heteroatomic and heterocyclic structures…”
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Investigator’s influence on the muscle strength assessment in animals in experiment: Comparison of automated “inverted grid” test and its classical variant
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (08-05-2024)“…The aim of the work was to study the influence of the researcher on the muscle strength assessment in animals in the experiment by comparing the results of the…”
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CONVENTIONAL APPROACHES TO THE THERAPY OF HEREDITARY MYOPATHIES
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2022)“…The aim of the work was to analyze the available therapeutic options for the conventional therapy of hereditary myopathies. Materials and methods. When…”
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Protective role of 3-oxypyridine derivatives in rats’ steroid-induced osteoporosis associated with reduced oxidative stress and recovery of nitric oxide formation
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (01-01-2023)“…From the point of view of the mechanisms for the implementation of pathogenetic links in the development of steroid-induced osteoporosis considered in the…”
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11-amino acid peptide imitating the structure of erythropoietin α-helix b improves endothelial function, but stimulates thrombosis in rats
Published in Farmaciâ i Farmakologiâ (Pâtigorsk) (2019)“…The aim of the study was to test whether P-αB can be positioned as a preventing and treating agent for cardiovascular diseases. Materials and methods. The…”
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A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats
Published in Bulletin of experimental biology and medicine (01-12-2011)“…Intragastric methionine (3 g/kg daily for 7 days) elevates homocysteine concentration and increases the endothelial dysfunction coefficient. This protocol of…”
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Comparative evaluation of the osteoprotective effects of resveratrol and resveratrol/enalapril combination in the treatment of experimental osteoporosis
Published in Ėksperimentalʹnaâ i kliničeskaâ farmacologiâ (2012)“…The osteoprotective effect of resveratrol and a combination of resveratrol with enalapril has been investigated in white Wistar female rats with experimental…”
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REALITIES AND PROSPECTS FOR PHARMACOLOGICAL CORRECTION OF «ADMA-ENOS"-ASSOCIATED WAYS IN PREECLAMPSIA
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (01-01-2010)“…Methylated analogs of L-arginine - asymmetric dimetilarginin (ADMA) and monometilarginin (L-NMMA) - are endogenous inhibitors of endothelial NO-synthase…”
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STUDY OF ENDOTHELIAL PROTECTIVE AND OSTEOPROTECTIVE PROPERTIES OF ROSUVASTATIN, L-NORVALINE AND THEIR COMBINATIONS IN EXPERIMENTAL OSTEOPOROSIS
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-12-2017)“…Aim. Study of the effectiveness of pharmacological management of experimental osteoporosis with rosuvastatin, L-norvaline and their combination in comparison…”
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Correction of endothelial dysfunction by L-arginine under experimental pre-eclampsia conditions
Published in Ėksperimentalʹnaâ i kliničeskaâ farmacologiâ (2012)“…The ADMA-like pre-eclampsia in pregnant rats was modeled by daily introduction of L-NAME in a dose of 25 mg/kg for 7 days. L-arginine (200 mg/kg) prevented the…”
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Pharmacological correction of experimental chronic limb ischemia
Published in Ėksperimentalʹnaâ i kliničeskaâ farmacologiâ (01-05-2008)“…In tests on a group of 250 rats, we studied (i) the level of microcirculation in the muscles of a healthy limb in the norm and (ii) the dynamics of…”
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Study of the mechanisms cardioprotektive effect of 3-(2,2,2- trimethylhydrazinium) propionate
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-02-2016)“…The work evaluated the influence of 3-(2,2,2-trimethylhydrazinium) propionate per square necrotic myocardium of the left ventricle and the level troponina I…”
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The study of antiosteoporotic action of nanoparticulated resveratrol and losartan
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-12-2014)“…The study demonstrated that eight weeks after ovariectomy in female white Wistar rats endothelial dysfunction of bone microvasculature and deterioration of…”
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Correction of endotoxin-induced endothelial dysfunction by recombinant erythropoetin and inhibitors of HMG-Co-A-reductase
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-12-2015)“…Using the combined use of recombinant erythropoietin «Darbopoetin alpha» (500 mcg / kg) with simvastatin, atorvastatin, rosuvastatin and rosuvastatin…”
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Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-10-2015)“…The use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling…”
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ENDOTHELIOPROTECTIVE AND CARDIOPROTECTIVE ACTIVITY OF SELECTIVE ARGINASE II INHIBITOR
Published in Kubanskiĭ nauchnyĭ medit︠s︡inskiĭ vestnik (01-06-2015)“…They researched endothelioprotective and cardioprotective activity of arginase II selective inhibitor (substance code ZB49-0010C) in model of L-NAME-induced…”
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