Search Results - "Gudmundsson, Olafur"

Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis by Williams, Nigel M, Dr, Zaharieva, Irina, BSc, Martin, Andrew, BSc, Langley, Kate, PhD, Mantripragada, Kiran, PhD, Fossdal, Ragnheidur, PhD, Stefansson, Hreinn, PhD, Stefansson, Kari, MD, Magnusson, Pall, MD, Gudmundsson, Olafur O, MD, Gustafsson, Omar, PhD, Holmans, Peter, Prof, Owen, Michael J, Prof, O'Donovan, Michael, Prof, Thapar, Anita, Prof

“…Summary Background Large, rare chromosomal deletions and duplications known as copy number variants (CNVs) have been implicated in neurodevelopmental disorders…”
Get full text

Application of Lipid-Based Formulations in Drug Discovery by Chen, Xue-Qing, Gudmundsson, Olafur S, Hageman, Michael J

Get full text

Maximizing biomass productivity and cell density of Chlorella vulgaris by using light-emitting diode-based photobioreactor by Fu, Weiqi, Gudmundsson, Olafur, Feist, Adam M., Herjolfsson, Gisli, Brynjolfsson, Sigurdur, Palsson, Bernhard Ø.

“…► Optimal performance data for light-emitting diodes based PBRs for microalgae is provided. ► We have addressed the convergence of microalgal biotechnology and…”
Get full text

Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder by Gudmundsson, Olafur O., Walters, G. Bragi, Ingason, Andres, Johansson, Stefan, Zayats, Tetyana, Athanasiu, Lavinia, Sonderby, Ida Elken, Gustafsson, Omar, Nawaz, Muhammad S., Jonsson, Gudbjorn F., Jonsson, Lina, Knappskog, Per-Morten, Ingvarsdottir, Ester, Davidsdottir, Katrin, Djurovic, Srdjan, Knudsen, Gun Peggy Strømstad, Askeland, Ragna Bugge, Haraldsdottir, Gyda S., Baldursson, Gisli, Magnusson, Pall, Sigurdsson, Engilbert, Gudbjartsson, Daniel F., Stefansson, Hreinn, Andreassen, Ole A., Haavik, Jan, Reichborn-Kjennerud, Ted, Stefansson, Kari

“…Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations…”
Get full text

Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery by Morgen, Michael, Saxena, Ajay, Chen, Xue-Qing, Miller, Warren, Nkansah, Richard, Goodwin, Aaron, Cape, Jon, Haskell, Roy, Su, Ching, Gudmundsson, Olafur, Hageman, Michael, Kumar, Anoop, Chowan, Gajendra Singh, Rao, Abhijith, Holenarsipur, Vinay K.

“…[Display omitted] Self-emulsifying drug delivery systems (SEDDS) have been used to solubilize poorly water-soluble drugs to improve exposure in high-dose…”
Get full text

Improved therapeutic index of an acidic pH-selective antibody by Lee, Peter S, MacDonald, Katherine G, Massi, Evan, Chew, Pamela V, Bee, Christine, Perkins, Padma, Chau, Bryant, Thudium, Kent, Lohre, Jack, Nandi, Pradyot, Deyanova, Ekaterina G, Barman, Ishita, Gudmundsson, Olafur, Dollinger, Gavin, Sproul, Tim, Engelhardt, John J, Strop, Pavel, Rajpal, Arvind

“…Although therapeutically efficacious, ipilimumab can exhibit dose-limiting toxicity that prevents maximal efficacious clinical outcomes and can lead to…”
Get full text

Diagnosis, rehabilitation and development of disability 2000-2019 in Iceland by Guðmundsson, Ólafur Ó, Hjaltalín, Guðmundur, Eggertsson, Haukur, Jónsdóttir, Þóra

“…INTRODUCTION: The disability assessment standard based on medically recognized illnesses or disabilities was introduced in Iceland 1999. The aim of this study…”
Get full text

Progress in understanding the structure–activity relationships of P-glycoprotein by Stouch, Terry R, Gudmundsson, Olafur

“…Efflux out of cells by P-glycoprotein (P-gp) represents a serious liability for pharmaceuticals, particularly for anti-cancer drugs. Consequently,…”
Get full text

Utility of gastric-retained alginate gels to modulate pharmacokinetic profiles in rats by Foster, Kimberly A, Sun, Huadong, Fancher, Roderick Marcus, Proszynski, Mirek, Dixon, George, Ford, Kenneth, Cornelius, Georgia, Gudmundsson, Olafur S, Hageman, Michael J

“…A gastric-retentive formulation amenable to dosing in rodents has the potential to enable sustained release in a preclinical setting. This may be useful to…”
Get more information

Utility of in situ sodium alginate/karaya gum gels to facilitate gastric retention in rodents by Foster, Kimberly A., Morgen, Mike, Murri, Brice, Yates, Ian, Fancher, R. Marcus, Ehrmann, Jon, Gudmundsson, Olafur S., Hageman, Michael J.

“…Barium sulfate suspension (left) and in situ gel containing barium sulfate (right) 1h post-dose. Target validation or demonstration of efficacy requires…”
Get full text

Psychiatric disorders in an urban sample of preschool children by Gudmundsson, Olafur O., Magnusson, Pall, Saemundsen, Evald, Lauth, Bertrand, Baldursson, Gisli, Skarphedinsson, Gudmundur, Fombonne, Eric

“…Background To increase limited epidemiological knowledge of early childhood psychopathology, a study of prevalence estimates and demographic correlates of…”
Get full text

A Probabilistic Tremor Location Method by Li, Ka Lok, Gudmundsson, Olafur

“…A method to locate tremor with an unclear onset is introduced. The method maps envelopes of cross‐correlated records from pairs of seismographs to signal…”
Get full text

Anomalous azimuthal variations with 360 degrees periodicity of Rayleigh phase velocities observed in Scandinavia by Mauerberger, Alexandra, Maupin, Valerie, Gudmundsson, Ólafur, Tilmann, Frederik

“…We use the recently deployed ScanArray network of broad-band stations covering most of Norway and Sweden as well as parts of Finland to analyse the propagation…”
Get full text

GSpecDisp: A matlab GUI package for phase-velocity dispersion measurements from ambient-noise correlations by Sadeghisorkhani, Hamzeh, Gudmundsson, Ólafur, Tryggvason, Ari

“…We present a graphical user interface (GUI) package to facilitate phase-velocity dispersion measurements of surface waves in noise-correlation traces. The…”
Get full text

Enhancement of carotenoid biosynthesis in the green microalga Dunaliella salina with light-emitting diodes and adaptive laboratory evolution by Fu, Weiqi, Guðmundsson, Ólafur, Paglia, Giuseppe, Herjólfsson, Gísli, Andrésson, Ólafur S., Palsson, Bernhard Ø., Brynjólfsson, Sigurður

“…There is a particularly high interest to derive carotenoids such as β-carotene and lutein from higher plants and algae for the global market. It is well known…”
Get full text

Discovery pharmaceutics--challenges and opportunities by Chen, Xue-Qing, Antman, Melissa D, Gesenberg, Christoph, Gudmundsson, Olafur S

“…Most pharmaceutical companies are now evaluating compounds for druglike properties early in the discovery process. The data generated at these early stages…”
Get full text

A shear-wave velocity model for the Scandinavian lithosphere from Rayleigh waves and ambient noise - Implications for the origin of the topography of the Scandes mountain range by Mauerberger, Alexandra, Sadeghisorkhani, Hamzeh, Maupin, Valérie, Gudmundsson, Ólafur, Tilmann, Frederik

“…We present a new 3D shear-wave velocity model and Moho map of Scandinavia, which is based on the inversion of the merged phase dispersion curves from ambient…”
Get full text

Depth to Moho in Greenland: receiver-function analysis suggests two Proterozoic blocks in Greenland by Dahl-Jensen, Trine, Larsen, Tine B, Woelbern, Ingo, Bach, Torben, Hanka, Winfried, Kind, Rainer, Gregersen, Søren, Mosegaard, Klaus, Voss, Peter, Gudmundsson, Olafur

“…The GLATIS project (Greenland Lithosphere Analysed Teleseismically on the Ice Sheet) with collaborators has operated a total of 16 temporary broadband…”
Get full text

Volcanic tremor of the 2010 Eyjafjallajökull eruption by Benediktsdóttir, Ásdís, Gudmundsson, Ólafur, Li, Ka Lok, Brandsdóttir, Bryndís

“…SUMMARY Volcanic eruptions in Iceland generally start with an increase in tremor levels. These signals do not have clear onset, like many earthquakes. As the…”
Get full text

Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells by Bhardwaj, Rajinder K, Herrera-Ruiz, Dea, Sinko, Patrick J, Gudmundsson, Olafur S, Knipp, Gregory

“…In the present investigation, the uptake and transport kinetics of valacyclovir (VACV), 5-aminolevulinic acid (5-ALA), and benzylpenicillin (BENZ) were studied…”
Get more information