Search Results - "Gubensek, Franc"

Evolutionary genomics of chromoviruses in eukaryotes by Gorinsek, Benjamin, Gubensek, Franc, Kordis, Dusan

“…The diversity, origin, and evolution of chromoviruses in Eukaryota were examined using the massive amount of genome sequence data for different eukaryotic…”
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Unusual Horizontal Transfer of a Long Interspersed Nuclear Element between Distant Vertebrate Classes by Kordis, Dusan, Gubensek, Franc

“…We have shown previously by Southern blot analysis that Bov-B long interspersed nuclear elements (LINEs) are present in different Viperidae snake species. To…”
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The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3 protein gamma and epsilon isoforms by Sribar, Jernej, Sherman, Nicholas E, Prijatelj, Petra, Faure, Grazyna, Gubensek, Franc, Fox, Jay W, Aitken, Alastair, Pungercar, Joze, Krizaj, Igor

“…Two novel acceptors for ammodytoxin C, a presynaptically neurotoxic phospholipase A(2) from snake venom, have been purified from porcine cerebral cortex by a…”
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Basic amino acid residues in the β-structure region contribute, but not critically, to presynaptic neurotoxicity of ammodytoxin A by Ivanovski, Gabriela, Petan, Toni, Križaj, Igor, Gelb, Michael H., Gubenšek, Franc, Pungerčar, Jože

“…The molecular mechanism of action of presynaptically toxic secreted phospholipases A 2 (sPLA 2s) isolated from snake venoms is not completely understood. It…”
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Adaptive evolution in the snake venom Kunitz/BPTI protein family by Zupunski, Vera, Kordis, Dusan, Gubensek, Franc

“…Snake venoms are rich sources of serine proteinase inhibitors that are members of the Kunitz/BPTI (bovine pancreatic trypsin inhibitor) family. However, only a…”
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Crotoxin acceptor protein isolated from Torpedo electric organ: binding properties to crotoxin by surface plasmon resonance by Faure, Grazyna, Čopič, Alenka, Porrier, Sabine Le, Gubenšek, Franc, Bon, Cassian, Križaj, Igor

“…Crotoxin, a potent neurotoxin from the South American rattlesnake Crotalus durissus terrificus, is a heterodimeric phospholipase A 2 (EC 3.1.1.4), which blocks…”
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Quantification of binding of some thiol-reactive clenbuterol analogues to bovine serum albumin by electron paramagnetic resonance spectroscopy by Preželj, Andrej, Štrancar, Janez, Gubenšek, Franc, Pečar, Slavko, Degand, Guy

“…The only free thiol group of bovine serum albumin (BSA) was coupled in a high yield with some novel thiol-reactive clenbuterol analogues. The unreacted…”
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Phylogenomic Analysis of the L1 Retrotransposons in Deuterostomia by Kordiš, Dušsan, Lovšin, Nika, Gubenšek, Franc, Shedlock, Andrew

“…L1 retrotransposons constitute the largest single component of mammalian genomes. In contrast to the single remaining lineage of L1 retrotransposons in…”
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Human Cathepsin B Is a Metastable Enzyme Stabilized by Specific Ionic Interactions Associated with the Active Site by Turk, Boris, Dolenc, Iztok, Zerovnik, Eva, Turk, Dusan, Gubensek, Franc, Turk, Vito

“…The effect of neutral or alkaline pH on cathepsin B activity and structure was investigated. An irreversible loss of activity, accompanied by large structural…”
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Identification of the Neuronal Acceptor in Bovine Cortex for Ammodytoxin C, a Presynaptically Neurotoxic Phospholipase A2 by Krizaj, Igor, Dolly, J. Oliver, Gubensek, Franc

“…A specific, high-affinity binding site for ammodytoxin C in synaptic membranes from bovine cerebral cortex was detected and partially characterized…”
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The C‐terminal region of ammodytoxins is important but not sufficient for neurotoxicity by Prijatelj, Petra, Križaj, Igor, Kralj, Bogdan, Gubenšek, Franc, Pungerčar, Jože

“…Ammodytoxins (Atxs) are presynaptically acting snake venom phospholipase A2 (PLA2) toxins the molecular mechanism of whose neurotoxicity is not completely…”
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Evolutionary dynamics and evolutionary history in the RTE clade of non-LTR retrotransposons by Zupunski, V, Gubensek, F, Kordis, D

“…This study examined the evolutionary dynamics of Bov-B LINEs in vertebrates and the evolution of the RTE clade of non-LTR retrotransposons. The first…”
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Evolutionary dynamics in a novel L2 clade of non-LTR retrotransposons in Deuterostomia by Lovsin, N, Gubensek, F, Kordi, D

“…The evolution of the novel L2 clade of non-long terminal repeat (LTR) retrotransposons and their evolutionary dynamics in Deuterostomia has been examined. The…”
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Purification and characterisation of two hemorrhagic metalloproteinases from the venom of the long-nosed viper, Vipera ammodytes ammodytes by Leonardi, Adrijana, Gubenšek, Franc, Križaj, Igor

“…Two hemorrhagic proteins, VaH1 and VaH2, have been purified from Vipera ammodytes ammodytes venom. They are monomeric glycoproteins of an apparent molecular…”
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Phenylalanine-24 in the N-terminal region of ammodytoxins is important for both enzymic activity and presynaptic toxicity by Petan, Toni, Krizaj, Igor, Gubensek, Franc, Pungercar, Joze

“…Ammodytoxins (Atxs) are group II phospholipases A(2) (PLA(2)s) with presynaptic toxicity from venom of the snake Vipera ammodytes ammodytes. The molecular…”
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Identification and Purification of a Novel Receptor for Secretory Phospholipase A2 in Porcine Cerebral Cortex by Copic, A, Vucemilo, N, Gubensek, F, Krizaj, I

“…A specific phospholipase A2receptor from porcine cerebral cortex has been characterized (Kd = 145 nm, Bmax = 0.4 pmol/mg membrane protein) by using a…”
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Equinatoxins, pore-forming proteins from the sea anemone Actinia equina, belong to a multigene family by Anderluh, Gregor, Križaj, Igor, Štrukelj, Borut, Gubenšek, Franc, Maček, Peter, Pungerčar, Jože

“…The multigene family of equinatoxins, pore-forming proteins from sea anemone Actinia equina, has been studied at the protein and gene levels. We report the…”
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Ammodytoxin, a secretory phospholipase A2, inhibits G2 cell-cycle arrest in the yeast Saccharomyces cerevisiae by Petrovic, Uros, Sribar, Jernej, Matis, Maja, Anderluh, Gregor, Peter-Katalinić, Jasna, Krizaj, Igor, Gubensek, Franc

“…Ammodytoxin (Atx), an sPLA2 (secretory phospholipase A2), binds to g and e isoforms of porcine 14-3-3 proteins in vitro. 14-3-3 proteins are evolutionarily…”
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Ammodytoxin, a neurotoxic secreted phospholipase A(2), can act in the cytosol of the nerve cell by Petrovic, Uros, Sribar, Jernej, Paris, Alenka, Rupnik, Marjan, Krzan, Mojca, Vardjan, Nina, Gubensek, Franc, Zorec, Robert, Krizaj, Igor

“…Recent identification of intracellular proteins that bind ammodytoxin (calmodulin, 14-3-3 proteins, and R25) suggests that this snake venom presynaptically…”
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The Bov-B lines found in Vipera ammodytes toxic PLA2 genes are widespread in snake genomes by Kordis, D, Gubensek, F

“…In the fourth intron of two toxic Vipera ammodytes PLA2 genes a Ruminantia specific 5'-truncated Bov-B LINE element was identified. Southern blot analysis of…”
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