Search Results - "Gubenšek, Franc"

Adaptive evolution in the snake venom Kunitz/BPTI protein family by Zupunski, Vera, Kordis, Dusan, Gubensek, Franc

“…Snake venoms are rich sources of serine proteinase inhibitors that are members of the Kunitz/BPTI (bovine pancreatic trypsin inhibitor) family. However, only a…”
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Phylogenomic Analysis of the L1 Retrotransposons in Deuterostomia by Kordiš, Dušsan, Lovšin, Nika, Gubenšek, Franc, Shedlock, Andrew

“…L1 retrotransposons constitute the largest single component of mammalian genomes. In contrast to the single remaining lineage of L1 retrotransposons in…”
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Evolutionary dynamics and evolutionary history in the RTE clade of non-LTR retrotransposons by Zupunski, V, Gubensek, F, Kordis, D

“…This study examined the evolutionary dynamics of Bov-B LINEs in vertebrates and the evolution of the RTE clade of non-LTR retrotransposons. The first…”
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Evolutionary dynamics in a novel L2 clade of non-LTR retrotransposons in Deuterostomia by Lovsin, N, Gubensek, F, Kordi, D

“…The evolution of the novel L2 clade of non-long terminal repeat (LTR) retrotransposons and their evolutionary dynamics in Deuterostomia has been examined. The…”
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Purification and characterisation of two hemorrhagic metalloproteinases from the venom of the long-nosed viper, Vipera ammodytes ammodytes by Leonardi, Adrijana, Gubenšek, Franc, Križaj, Igor

“…Two hemorrhagic proteins, VaH1 and VaH2, have been purified from Vipera ammodytes ammodytes venom. They are monomeric glycoproteins of an apparent molecular…”
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Phenylalanine-24 in the N-terminal region of ammodytoxins is important for both enzymic activity and presynaptic toxicity by Petan, Toni, Krizaj, Igor, Gubensek, Franc, Pungercar, Joze

“…Ammodytoxins (Atxs) are group II phospholipases A(2) (PLA(2)s) with presynaptic toxicity from venom of the snake Vipera ammodytes ammodytes. The molecular…”
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Identification and Purification of a Novel Receptor for Secretory Phospholipase A2 in Porcine Cerebral Cortex by Copic, A, Vucemilo, N, Gubensek, F, Krizaj, I

“…A specific phospholipase A2receptor from porcine cerebral cortex has been characterized (Kd = 145 nm, Bmax = 0.4 pmol/mg membrane protein) by using a…”
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Equinatoxins, pore-forming proteins from the sea anemone Actinia equina, belong to a multigene family by Anderluh, Gregor, Križaj, Igor, Štrukelj, Borut, Gubenšek, Franc, Maček, Peter, Pungerčar, Jože

“…The multigene family of equinatoxins, pore-forming proteins from sea anemone Actinia equina, has been studied at the protein and gene levels. We report the…”
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Evolutionary genomics of chromoviruses in eukaryotes by Gorinsek, Benjamin, Gubensek, Franc, Kordis, Dusan

“…The diversity, origin, and evolution of chromoviruses in Eukaryota were examined using the massive amount of genome sequence data for different eukaryotic…”
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Ammodytoxin, a secretory phospholipase A2, inhibits G2 cell-cycle arrest in the yeast Saccharomyces cerevisiae by Petrovic, Uros, Sribar, Jernej, Matis, Maja, Anderluh, Gregor, Peter-Katalinić, Jasna, Krizaj, Igor, Gubensek, Franc

“…Ammodytoxin (Atx), an sPLA2 (secretory phospholipase A2), binds to g and e isoforms of porcine 14-3-3 proteins in vitro. 14-3-3 proteins are evolutionarily…”
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The Bov-B lines found in Vipera ammodytes toxic PLA2 genes are widespread in snake genomes by Kordis, D, Gubensek, F

“…In the fourth intron of two toxic Vipera ammodytes PLA2 genes a Ruminantia specific 5'-truncated Bov-B LINE element was identified. Southern blot analysis of…”
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Identification of a novel binding site for calmodulin in ammodytoxin A, a neurotoxic group IIA phospholipase A2 by Prijatelj, Petra, Šribar, Jernej, Ivanovski, Gabriela, Križaj, Igor, Gubenšek, Franc, Pungerčar, Jože

“…The molecular mechanism of the presynaptic neurotoxicity of snake venom phospholipases A2 (PLA2s) is not yet fully elucidated. Recently, new high‐affinity…”
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The effect of ammodytin L on frog neuromuscular junction by Horvat-nidarsic, Irena, Suput, Dusan, Gubensek, Franc

“…Effects of myotoxic ammodytin L on frog neuromuscular junction were examined by morphological, enzymatic and electrophysiological studies. Electron micrographs…”
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Bov‐B Long Interspersed Repeated DNA (LINE) Sequences are Present in Vipera Ammodytes Phospholipase A2 Genes and in Genomes of Viperidae Snakes by Kordis, D, Gubensek, F

“…Ammodytin L is a myotoxic Ser49 phospholipase A2 (PLA2) homologue, which is tissue‐specifically expressed in the venom glands of Vipera ammodytes. The complete…”
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Unusual Horizontal Transfer of a Long Interspersed Nuclear Element between Distant Vertebrate Classes by Kordis, Dusan, Gubensek, Franc

“…We have shown previously by Southern blot analysis that Bov-B long interspersed nuclear elements (LINEs) are present in different Viperidae snake species. To…”
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Molecular cloning and chimerisation of CDI 315B monoclonal antibody by Kopitar-jerala, Natasa, Bestagno, Marco, Fan, Xiaohui, Novak-despot, Djurdja, Burrone, Oscar, Kos, Janko, Skrk, Janez, Gubensek, Franc

“…A chimeric mouse-human antibody has been created that recognizes an antigen found on breast cancer cells and melanoma cells. Immunoglobulin constant domains of…”
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Adaptive evolution of animal toxin multigene families by Kordis, D, Gubensek, F

“…Animal toxins comprise a diverse array of proteins that have a variety of biochemical and pharmacological functions. A large number of animal toxins are…”
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Effects of ammodytin L on miniature and endplate potentials in neuromuscular junction of frog m. cutaneus pectoris by Frangez, R, Krizaj, I, Gubensek, F, Suput, D

“…Neurotoxic effects of ammodytin L (AtnL), a potent phospholipase A2 homologue, was studied in frog neuromuscular preparation m. cutaneous pectoris by measuring…”
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Re-examination of crotoxin-membrane interactions by Krizaj, Igor, Faure, Grazyna, Gubensek, Franc, Bon, Cassian

“…The interaction of crotoxin with synaptic membranes from Torpedo marmorata has been re-examined, using radioiodinated toxin. In competition experiments, the…”
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Sequence analysis of the cDNA encoding the precursor of equinatoxin V, a newly discovered hemolysin from the sea anemone Actinia equina by Pungerčar, Jože, Anderluh, Gregor, Maček, Peter, Franc, Gubenšek, Štrukelj, Borut

“…A cDNA encoding the 214-amino-acid (aa) precursor of equinatoxin V (EqtV) has been isolated from an Actinia equina cDNA library. The sequence of the mature…”
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