Search Results - "Guatimosim, S."

Homeostatic plasticity induced by increased acetylcholine release at the mouse neuromuscular junction by Camargo, WL, Kushmerick, C, Pinto, EKR, Souza, NMV, Cavalcante, WLG, Souza-Neto, FP, Guatimosim, S, Prado, MAM, Guatimosim, C, Naves, LA

“…At the neuromuscular junction (NMJ), changes to the size of the postsynaptic potential induce homeostatic compensation. At the Drosophila NMJ, increased…”
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Testosterone deficiency prevents left ventricular contractility dysfunction after myocardial infarction by Ribeiro Júnior, R.F., Ronconi, K.S., Jesus, I.C.G., Almeida, P.W.M., Forechi, L., Vassallo, D.V., Guatimosim, S., Stefanon, I., Fernandes, A.A.

“…Testosterone may affect myocardial contractility since its deficiency decreases the contraction and relaxation of the heart. Meanwhile, testosterone…”
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Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice by Oliveira, R. S. F., Ferreira, J. C. B., Gomes, E. R. M., Paixão, N. A., Rolim, N. P. L., Medeiros, A., Guatimosim, S., Brum, P. C.

“…Cardiomyocyte hypertrophy occurs in response to a variety of physiological and pathological stimuli. While pathological hypertrophy in heart failure is usually…”
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Highly efficient siRNA delivery system into human and murine cells using single-wall carbon nanotubes by Ladeira, M S, Andrade, V A, Gomes, E R M, Aguiar, C J, Moraes, E R, Soares, J S, Silva, E E, Lacerda, R G, Ladeira, L O, Jorio, A, Lima, P, Leite, M Fatima, Resende, R R, Guatimosim, S

“…Development of RNA interference (RNAi) technology utilizing short interfering RNA sequences (siRNA) has focused on creating methods for delivering siRNAs to…”
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Influence of spontaneous calcium events on cell-cycle progression in embryonal carcinoma and adult stem cells by Resende, R.R., Adhikari, A., da Costa, J.L, Lorençon, E., Ladeira, M.S., Guatimosim, S., Kihara, A.H., Ladeira, L.O.

“…Spontaneous Ca 2+ events have been observed in diverse stem cell lines, including carcinoma and mesenchymal stem cells. Interestingly, during cell cycle…”
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Functionalized nanomaterials: are they effective to perform gene delivery to difficult-to-transfect cells with no cytotoxicity? by Tonelli, F M P, Lacerda, S M S N, Paiva, N C O, Pacheco, F G, Scalzo Junior, S R A, de Macedo, F H P, Cruz, J S, Pinto, M C X, Corrêa Junior, J D, Ladeira, L O, França, L R, Guatimosim, S, Resende, R R

“…Nanodiamonds (NDs), multiwalled carbon nanotubes (MWCNTs) and gold nanorods (NRs) can be functionalized to promote gene delivery to hard-to-transfect cells…”
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Cardiovascular autonomic regulation in mice overexpressing the vesicular acetylcholine transporter (VAChT) gene by Tezini, G.C.S.V, Silva, L.E.V, Oliveira, M, Guatimosim, S, Fazan, R, Prado, V.F, Prado, M.A.M, Salgado, H.C

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Heart failure after myocardial infarction : Altered excitation-contraction coupling by GOMEZ, A. M, GUATIMOSIM, S, DILLY, K. W, VASSORT, G, LEDERER, W. J

“…Heart failure (HF) frequently follows the occurrence of myocardial infarction (MI). Questions about how HF develops and what cellular defects contribute to…”
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Heart Failure After Myocardial Infarction by Gómez, Ana Maria, Guatimosim, S., Dilly, K.W., Vassort, G., Lederer, W.J.

“…Background — Heart failure (HF) frequently follows the occurrence of myocardial infarction (MI). Questions about how HF develops and what cellular defects…”
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Molecular cloning and genomic analysis of TsNTxp: an immunogenic protein from Tityus serrulatus scorpion venom by Guatimosim, Silvia C, Prado, Vania F, Diniz, Carlos R, Chávez-Olórtegui, Carlos, Kalapothakis, Evanguedes

“…A non-toxic protein (TsNTxP) from Tityus serrulatus scorpion venom has been shown to be an efficient immunogen and anti-TsNTxP antibodies recognize and…”
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Induction of neutralizing antibodies against Tityus serrulatus toxins by immunization with a recombinant nontoxic protein by Guatimosim, Silvia C.F., Kalapothakis, Evanguedes, Diniz, Carlos R., Chávez-Olórtegui, Carlos

“…An immunogenic nontoxic protein (TsNTxP) was purified from the venom of the scorpion Tityus serrulatus (Ts). This peptide is composed of 63 amino acid residues…”
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Ionizable Lipid Nanoparticle-Mediated Delivery of Plasmid DNA in Cardiomyocytes by Scalzo, Sergio, Santos, Anderson K, Ferreira, Heloisa A.S, Costa, Pedro A, Prazeres, Pedro H.D.M, da Silva, Natalia J.A, Guimaraes, Lays C, e Silva, Mario de Morais, Alves, Marco T.R. Rodrigues, Viana, Celso T.R, Jesus, Itamar C.G, Rodrigues, Alice P, Birbrair, Alexander, Lobo, Anderson O, Frezard, Frederic, Mitchell, Michael J, Guatimosim, Silvia, Guimaraes, Pedro Pires Goulart

“…Introduction: Gene therapy is a promising approach to be applied in cardiac regeneration after myocardial infarction and gene correction for inherited…”
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Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering by Tonelli, Fernanda M P, Santos, Anderson K, Gomes, Katia N, Lorençon, Eudes, Guatimosim, Silvia, Ladeira, Luiz O, Resende, Rodrigo R

“…In recent years, significant progress has been made in organ transplantation, surgical reconstruction, and the use of artificial prostheses to treat the loss…”
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Calmodulin kinase II inhibition protects against structural heart disease by Anderson, Mark E, Zhang, Rong, Khoo, Michelle S C, Wu, Yuejin, Yang, Yingbo, Grueter, Chad E, Ni, Gemin, Price, Edward E, Thiel, William, Guatimosim, Silvia, Song, Long-Sheng, Madu, Ernest C, Shah, Anisha N, Vishnivetskaya, Tatiana A, Atkinson, James B, Gurevich, Vsevolod V, Salama, Guy, Lederer, W J, Colbran, Roger J

“…Beta-adrenergic receptor (betaAR) stimulation increases cytosolic Ca(2+) to physiologically augment cardiac contraction, whereas excessive betaAR activation…”
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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death by Bennett, Vann, Mohler, Peter J, Schott, Jean-Jacques, Gramolini, Anthony O, Dilly, Keith W, Guatimosim, Silvia, duBell, William H, Song, Long-Sheng, Haurogné, Karine, Kyndt, Florence, Ali, Mervat E, Rogers, Terry B, Lederer, W. J, Escande, Denis, Marec, Herve Le

“…Mutations in ion channels involved in the generation and termination of action potentials constitute a family of molecular defects that underlie fatal cardiac…”
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FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death by Wehrens, Xander H.T., Lehnart, Stephan E., Huang, Fannie, Vest, John A., Reiken, Steven R., Mohler, Peter J., Sun, Jie, Guatimosim, Silvia, Song, Long-Sheng, Rosemblit, Nora, D'Armiento, Jeanine M., Napolitano, Carlo, Memmi, Mirella, Priori, Silvia G., Lederer, W.J., Marks, Andrew R.

“…Arrhythmias, a common cause of sudden cardiac death, can occur in structurally normal hearts, although the mechanism is not known. In cardiac muscle, the…”
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Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol by Reiken, Steven, Gaburjakova, Marta, Guatimosim, Silvia, Gomez, Ana M, D'Armiento, Jeanine, Burkhoff, Daniel, Wang, Jie, Vassort, Guy, Lederer, W Jonathan, Marks, Andrew R

“…The cardiac ryanodine receptor/calcium release channel (RyR2) on the sarcoplasmic reticulum (SR) comprises a macromolecular complex that includes a kinase and…”
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Nuclear Inositol 1,4,5-Triphosphate is an Absolut Requirement for Cardiomyocyte Hypertrophy by Arantes, Lilian M., Aguiar, Carla J., Amaya, M. Jimena, Guatimosim, S., Leite, M. Fátima

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The Ca2+ leak paradox and “rogue ryanodine receptors”: SR Ca2+ efflux theory and practice by SOBIE, E, GUATIMOSIM, S, GOMEZVIQUEZ, L, SONG, L, HARTMANN, H, SALEETJAFRI, M, LEDERER, W

“…Ca 2+ efflux from the sarcoplasmic reticulum (SR) is routed primarily through SR Ca 2+ release channels (ryanodine receptors, RyRs). When clusters of RyRs are…”
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Cardiomyocyte dysfunction during the chronic phase of Chagas disease by Roman-Campos, Danilo, Sales-Júnior, Policarpo, Duarte, Hugo Leonardo, Gomes, Eneas Ricardo, Guatimosim, Silvia, Ropert, Catherine, Gazzinelli, Ricardo Tostes, Cruz, Jader Santos

“…Chagas disease, which is caused by the parasite Trypanosoma cruzi, is an important cause of heart failure. We investigated modifications in the cellular…”
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