Search Results - "Guatelli, John C."

BST-2/tetherin: a new component of the innate immune response to enveloped viruses by Evans, David T, Serra-Moreno, Ruth, Singh, Rajendra K, Guatelli, John C

“…The interferon-inducible, transmembrane protein BST-2 (CD317, tetherin) directly holds fully formed enveloped virus particles to the cells that produce them,…”
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Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu by TOKAREV, Andrey A, MUNGUIA, Jason, GUATELLI, John C

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Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking by Mitchell, Richard S, Katsura, Chris, Skasko, Mark A, Fitzpatrick, Katie, Lau, David, Ruiz, Autumn, Stephens, Edward B, Margottin-Goguet, Florence, Benarous, Richard, Guatelli, John C

“…The interferon-induced transmembrane protein BST-2/CD317 (tetherin) restricts the release of diverse enveloped viruses from infected cells. The HIV-1 accessory…”
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HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment by Hauser, Heiko, Lopez, Lisa A, Yang, Su Jung, Oldenburg, Jill E, Exline, Colin M, Guatelli, John C, Cannon, Paula M

“…In the absence of the Vpu protein, newly formed HIV-1 particles can remain attached to the surface of human cells due to the action of an interferon-inducible…”
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Cooperative Binding of the Class I Major Histocompatibility Complex Cytoplasmic Domain and Human Immunodeficiency Virus Type 1 Nef to the Endosomal AP-1 Complex via Its μ Subunit by NOVIELLO, Colleen M, BENICHOU, Serge, GUATELLI, John C

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Effects of Alpha Interferon Treatment on Intrinsic Anti-HIV-1 Immunity In Vivo by Abdel-Mohsen, Mohamed, Deng, Xutao, Liegler, Teri, Guatelli, John C, Salama, Mohamed S, A Ghanem, Hussam El-din, Rauch, Andri, Ledergerber, Bruno, Deeks, Steven G, Guenthard, Huldrych F

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An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex by Singh, Rajendra Kumar, Lau, David, Noviello, Colleen M, Ghosh, Partho, Guatelli, John C

“…The down-regulation of the major histocompatibility complex class I (MHC-I) from the surface of infected cells by the Nef proteins of primate immunodeficiency…”
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The Vpu protein: new concepts in virus release and CD4 down-modulation by Ruiz, Autumn, Guatelli, John C, Stephens, Edward B

“…Human immunodeficiency virus type 1 (HIV-1) and several simian immunodeficiency viruses (SIV) encode for a transmembrane protein known as Vpu (viral protein…”
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Interaction of HIV-1 Nef with the Cellular Dileucine-Based Sorting Pathway is Required for CD4 Down-Regulation and Optimal Viral Infectivity by Craig, Heather M., Pandori, Mark W., Guatelli, John C.

“…The HIV-1 Nef protein is important for pathogenesis, enhances viral infectivity, and regulates the sorting of at least two cellular transmembrane proteins, CD4…”
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The Membrane-Proximal Tyrosine-Based Sorting Signal of Human Immunodeficiency Virus Type 1 gp41 Is Required for Optimal Viral Infectivity by Day, J R, Muenk, C, Guatelli, J C

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Long-term Persistence of Zoster Vaccine Efficacy by Morrison, Vicki A., Johnson, Gary R., Schmader, Kenneth E., Levin, Myron J., Zhang, Jane H., Looney, David J., Betts, Robert, Gelb, Larry, Guatelli, John C., Harbecke, Ruth, Pachucki, Connie, Keay, Susan, Menzies, Barbara, Griffin, Marie R., Kauffman, Carol A., Marques, Adriana, Toney, John, Boardman, Kathy, Su, Shu-Chih, Li, Xiaoming, Chan, Ivan S. F., Parrino, Janie, Annunziato, Paula, Oxman, Michael N.

“…Background. The Shingles Prevention Study (SPS) demonstrated zoster vaccine efficacy through 4 years postvaccination. A Short-Term Persistence Substudy (STPS)…”
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HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment by Hauser, Heiko, Lopez, Lisa A, Yang, Su Jung, Oldenburg, Jill E, Exline, Colin M, Guatelli, John C, Cannon, Paula M

“…Author details1-Keck School of Medicine of the University of Southern California, California Los Angeles, CA 90089, USAEMPTY2-University of California San…”
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Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5 by Angerstein, Aaron O., Stoneham, Charlotte A., Ramirez, Peter W., Guatelli, John C., Vollbrecht, Thomas

“…The host protein SERINC5 inhibits the infectivity of HIV-1 virions in an Env-dependent manner and is counteracted by Nef. The conformation of the Env trimer…”
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Competition Model for Upregulation of the Major Histocompatibility Complex Class II-Associated Invariant Chain by Human Immunodeficiency Virus Type 1 Nef by MITCHELL, Richard S, CHAUDHURI, Rittik, WOLF LINDWASSER, O, TANAKA, Kristie A, LAU, David, MURILLO, Rudy, BONIFACINO, Juan S, GUATELLI, John C

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Corrigendum to “Sensitivity to monoclonal antibody 447-52D and an open env trimer conformation correlate poorly with inhibition of HIV-1 infectivity by SERINC5” [Virology 2020 548, 73–81] by Angerstein, Aaron O., Stoneham, Charlotte A., Ramirez, Peter W., Guatelli, John C., Vollbrecht, Thomas

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Modulation of Cellular Protein Trafficking by Human Immunodeficiency Virus Type 1 Nef: Role of the Acidic Residue in the ExxxLL Motif by COLEMAN, Scott H, MADRID, Ricardo, VAN DAMME, Nanette, MITCHELL, Richard S, BOUCHET, Jerome, SERVANT, Cecile, PILLAI, Satish, BENICHOU, Serge, GUATELLI, John C

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Leucine-Specific, Functional Interactions between Human Immunodeficiency Virus Type 1 Nef and Adaptor Protein Complexes by COLEMAN, Scott H, VAN DAMME, Nanette, DAY, John R, NOVIELLO, Colleen M, HITCHIN, Douglas, MADRID, Ricardo, BENICHOU, Serge, GUATELLI, John C

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Inconsistent reversal of HIV-1 latency ex vivo by antigens of HIV-1, CMV, and other infectious agents by Vollbrecht, Thomas, Angerstein, Aaron O, Menke, Bryson, Kumar, Nikesh M, de Oliveira, Michelli Faria, Richman, Douglas D, Guatelli, John C

“…A reservoir of replication-competent but latent virus is the main obstacle to a cure for HIV-1 infection. Much of this reservoir resides in memory CD4 T cells…”
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Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster by Morrison, Vicki A., Oxman, Michael N., Levin, Myron J., Schmader, Kenneth E., Guatelli, John C., Betts, Robert F., Gelb, Larry D., Pachucki, Constance T., Keay, Susan K., Menzies, Barbara, Griffin, Marie R., Kauffman, Carol A., Marques, Adriana R., Toney, John F., Simberkoff, Michael S., Serrao, Richard, Arbeit, Robert D., Gnann, John W., Greenberg, Richard N., Holodniy, Mark, Keitel, Wendy A., Yeh, Shingshing S., Davis, Larry E., Crawford, George E., Neuzil, Kathy M., Johnson, Gary R., Zhang, Jane H., Harbecke, Rith, Chan, Ivan S. F., Keller, Paul M., Williams, Heather M., Boardman, Kathy D., Silber, Jeffrey L., Annunziato, Paula W.

“…Background. After completion of the Shingles Prevention Study (SPS; Department of Veterans Affairs Cooperative Studies Program Number 403), SPS participants…”
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BST-2 mediated restriction of simian–human immunodeficiency virus by Ruiz, Autumn, Lau, David, Mitchell, Richard S, Hill, M. Sarah, Schmitt, Kimberly, Guatelli, John C, Stephens, Edward B

“…Abstract Pathogenic simian–human immunodeficiency viruses (SHIV) contain HIV-1 Vpu and SIV Nef, both shown to counteract BST-2 (HM1.24; CD317; tetherin)…”
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