Search Results - "Guarini, Chiara"
-
1
Beyond RAS and BRAF: HER2, a New Actionable Oncotarget in Advanced Colorectal Cancer
Published in International journal of molecular sciences (01-07-2021)“…The human epidermal growth factor receptor 2 (HER2) is a well-established oncogenic driver and a successful therapeutic target in several malignancies, such as…”
Get full text
Journal Article -
2
The Resistance to EGFR-TKIs in Non-Small Cell Lung Cancer: From Molecular Mechanisms to Clinical Application of New Therapeutic Strategies
Published in Pharmaceutics (27-05-2023)“…Almost 17% of Western patients affected by non-small cell lung cancer (NSCLC) have an activating epidermal growth factor receptor (EGFR) gene mutation. Del19…”
Get full text
Journal Article -
3
Immunotherapy in Prostate Cancer: State of Art and New Therapeutic Perspectives
Published in Current oncology (Toronto) (01-06-2023)“…Prostate cancer (PC) is the most common type of tumor in men. In the early stage of the disease, it is sensitive to androgen deprivation therapy. In patients…”
Get full text
Journal Article -
4
Immunotherapy and Pancreatic Cancer: A Lost Challenge?
Published in Life (Basel, Switzerland) (30-06-2023)“…Although immunotherapy has proved to be a very efficient therapeutic strategy for many types of tumors, the results for pancreatic cancer (PC) have been very…”
Get full text
Journal Article -
5
Synergizing Immunotherapy and Antibody-Drug Conjugates: New Horizons in Breast Cancer Therapy
Published in Pharmaceutics (29-08-2024)“…The advent of immunotherapy and antibody-drug conjugates (ADCs) have revolutionized breast cancer treatment, offering new hope to patients. However,…”
Get full text
Journal Article -
6
Immunonutrition, Metabolism, and Programmed Cell Death in Lung Cancer: Translating Bench to Bedside
Published in Biology (Basel, Switzerland) (01-06-2024)“…Lung cancer presents significant therapeutic challenges, motivating the exploration of novel treatment strategies. Programmed cell death (PCD) mechanisms,…”
Get full text
Journal Article -
7
Early-stage triple negative breast cancer: the therapeutic role of immunotherapy and the prognostic value of pathological complete response
Published in Exploration of targeted anti-tumor therapy (2024)“…Triple negative breast cancer (TNBC) represents an aggressive disease associated with a high risk of recurrence after curative treatment and a poor prognosis…”
Get full text
Journal Article -
8
Advances in pharmacotherapies that target the cell cycle for treatment of breast cancer: where are we at today?
Published in Expert opinion on pharmacotherapy (24-05-2023)“…Advances in pharmacotherapies that target cell cycle in breast cancer have transformed the therapeutic armamentarium of breast oncology leading to the approval…”
Get more information
Journal Article -
9
Evaluating CDK4/6 Inhibitor Therapy in Elderly Patients with Metastatic Hormone Receptor-Positive, HER2-Negative Breast Cancer: A Retrospective Real-World Multicenter Study
Published in Cancers (10-10-2024)“…Metastatic HR+/HER2- breast cancer is commonly treated with CDK4/6 inhibitors in combination with endocrine therapy. However, the efficacy and safety of this…”
Get full text
Journal Article -
10
Antibody-Drug Conjugates in HR+ Breast Cancer: Where Are We Now and Where Are We Heading?
Published in Journal of clinical medicine (26-11-2023)“…Hormone receptor-positive (HR+) breast cancer (BC) accounts for about 60-70% of all diagnosed BCs, and endocrine therapy has long been the hallmark of systemic…”
Get full text
Journal Article -
11
The Treatment Landscape of Elderly Patients with Hormone Receptor-Positive Her2 Negative Advanced Breast Cancer: Current Perspectives and Future Directions
Published in Journal of clinical medicine (01-09-2023)“…Breast cancer (BC) in elderly women is an increasing health issue due to demographic changes. BC tends to present later and may receive less than standard…”
Get full text
Journal Article