Search Results - "Guanglin, Lei"

Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients by Zhu, Linnan, Yang, Penghui, Zhao, Yingze, Zhuang, Zhenkun, Wang, Zhifeng, Song, Rui, Zhang, Jie, Liu, Chuanyu, Gao, Qianqian, Xu, Qumiao, Wei, Xiaoyu, Sun, Hai-Xi, Ye, Beiwei, Wu, Yanan, Zhang, Ning, Lei, Guanglin, Yu, Lingxiang, Yan, Jin, Diao, Guanghao, Meng, Fanping, Bai, Changqing, Mao, Panyong, Yu, Yeya, Wang, Mingyue, Yuan, Yue, Deng, Qiuting, Li, Ziyi, Huang, Yunting, Hu, Guohai, Liu, Yang, Wang, Xiaoqian, Xu, Ziqian, Liu, Peipei, Bi, Yuhai, Shi, Yi, Zhang, Shaogeng, Chen, Zhihai, Wang, Jian, Xu, Xun, Wu, Guizhen, Wang, Fu-Sheng, Gao, George F., Liu, Longqi, Liu, William J.

“…The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide public health threat. However, little is known about its hallmarks compared to…”
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Integrated gut virome and bacteriome dynamics in COVID-19 patients by Cao, Jiabao, Wang, Cheng, Zhang, Yuqing, Lei, Guanglin, Xu, Kun, Zhao, Na, Lu, Jingjing, Meng, Fanping, Yu, Linxiang, Yan, Jin, Bai, Changqing, Zhang, Shaogeng, Zhang, Ning, Gong, Yuhuan, Bi, Yuhai, Shi, Yi, Chen, Zhu, Dai, Lianpan, Wang, Jun, Yang, Penghui

“…SARS-CoV-2 is the cause of the current global pandemic of COVID-19; this virus infects multiple organs, such as the lungs and gastrointestinal tract. The…”
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Intestinal Candida albicans Promotes Hepatocarcinogenesis by Up-Regulating NLRP6 by Liu, Zherui, Li, Yinyin, Li, Chen, Lei, Guanglin, Zhou, Lin, Chen, Xiangling, Jia, Xiaodong, Lu, Yinying

“…Hepatocellular carcinoma (HCC), a primary liver cancer, is closely associated with the gut microbiota. However, the role of gut fungi in the development of HCC…”
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D2D Communication Mode Selection and Resource Optimization Algorithm With Optimal Throughput in 5G Network by Li, Jun, Lei, Guanglin, Manogaran, Gunasekaran, Mastorakis, George, X. Mavromoustakis, Constandinos

“…Aiming at the problem of device-to-device (D2D) communication mode selection and resource optimization under the joint resource allocation mode in the 5G…”
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Oncolytic Activity of a Chimeric Influenza A Virus Carrying a Human CTLA4 Antibody in Hepatocellular Carcinoma by Yang, Hao, Lei, Guanglin, Sun, Fang, Cheng, Jinxia, Yan, Jin, Zhang, Shaogeng, Yang, Penghui

“…Oncolytic virotherapy belongs to a kind of active immunotherapy, which could trigger a potent antitumor immune response, showing great potential in clinical…”
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Decreased granzyme-B expression in CD11c + CD8 + T cells associated with disease progression in patients with HBV-related hepatocellular carcinoma by Gao, Lin, Hong, Zhixian, Lei, Guanglin, Guo, An-Liang, Wang, Fu-Sheng, Jiao, Yan-Mei, Fu, Junliang

“…CD11c CD8 T cells are an unconventional CD8 T cell subset that exerts antiviral activity in infectious diseases. However, its characteristics in hepatocellular…”
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Downregulated miR-451a as a feature of the plasma cfRNA landscape reveals regulatory networks of IL-6/IL-6R-associated cytokine storms in COVID-19 patients by Yang, Penghui, Zhao, Yingze, Li, Jie, Liu, Chuanyu, Zhu, Linnan, Zhang, Jie, Yu, Yeya, Wang, Wen-Jing, Lei, Guanglin, Yan, Jin, Sun, Fang, Bian, Chengrong, Meng, Fanping, Xu, Zhe, Bai, Changqing, Ye, Beiwei, Guo, Yuanyuan, Shu, Liumei, Yuan, Xiaoju, Zhang, Ning, Bi, Yuhai, Shi, Yi, Wu, Guizhen, Zhang, Shaogeng, Gao, George F., Liu, Longqi, Liu, William J., Sun, Hai-Xi

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A chimeric influenza virus vaccine expressing fusion protein epitopes induces protection from human metapneumovirus challenge in mice by Chongyu, Tian, Guanglin, Lei, Fang, Sun, Zhuoya, Deng, Hao, Yang, Cong, Li, Xinyu, Li, Wei, He, Lingyun, Tan, Yan, Niu, Penghui, Yang

“…Human metapneumovirus (HMPV) is a common virus associated with acute respiratory distress syndrome in pediatric patients. There are no HMPV vaccines or…”
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Oncolytic Activity of a Novel Influenza A Virus Carrying Granulocyte-Macrophage Colony-Stimulating Factor in Hepatocellular Carcinoma by Penghui, Yang, Fang, Sun, Ruilan, Wang, Guanglin, Lei, Hongjing, Gu, Yueqiang, Duan, Zhongpeng, Zhao, Xiaolan, Yang, Zhaohai, Wang, Shaogeng, Zhang, Xiliang, Wang

“…Oncolytic virotherapy is a promising strategy for the treatment of cancer. Influenza A virus has shown potential as an oncolytic agent. In this study, a…”
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Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma by Cheng, Sijie, Li, Tieling, Wang, Cheng, Wang, Keyu, Lai, Chengcai, Yan, Jin, Fan, Hongxia, Sun, Fang, Wang, Zhaohai, Zhang, Peirui, Yu, Linxiang, Hong, Zhixian, Lei, Guanglin, Sun, Baijun, Gao, Yuan, Xiao, Zhaohui, Ji, Xu, Wang, Ruilan, Wu, Jianzhong, Wang, Xiliang, Zhang, Shaogeng, Yang, Penghui

“…Hepatocellular carcinoma (HCC) is the most common neoplasm and is a leading cause of cancer-related death. Despite advances in the diagnosis and management of…”
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Donafenib, anti-PD-1 antibodies, plus hepatic arterial infusion chemotherapy (HAIC) as conversion therapy in patients with initially unresectable hepatocellular carcinoma (HCC): A prospective, single-arm, phase 2 study by Hong, Zhixian, Lei, Guanglin, Song, Biao, Hu, Xiongwei, Wang, Sen

“…e16140 Background: Most patients with hepatocellular carcinomas (HCC) are diagnosed at intermediate to advanced stages, at which they have missed the…”
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Identification of a new five-gene risk score for risk stratification and prognosis prediction in HCC by Li, Zhi, Lei, Guanglin, Meng, Xuan, Yang, Zhanyu

“…Approximately 80% of primary liver cancer (PLC) is hepatocellular carcinoma (HCC), and the prognosis of HCC patients is unfavorable. Further studies are…”
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Therapeutic Efficacy of an Oncolytic Influenza Virus Carrying an Antibody Against Programmed Cell Death 1 in Hepatocellular Carcinoma by Lei, Guanglin, Li, Baofa, Yang, Hao, Sun, Fang, Li, Donghui, Yan, Jin, Wang, Yonggang, Li, Ruisheng, Liu, Honghong, Zhang, Shaogeng, Li, Yufeng, Yang, Penghui

“…Oncolytic virus therapy is a promising novel immunotherapy. In this report, we engineered a novel oncolytic influenza virus (IV) carrying an antihuman…”
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Enhanced NK cell activation via eEF2K-mediated potentiation of the cGAS–STING pathway in hepatocellular carcinoma by Xu, Yan, Sun, Fang, Tian, Yuying, Zeng, Guineng, Lei, Guanglin, Bai, Zhifang, Wang, Yonggang, Ge, Xinlan, Wang, Jing, Xiao, Chaohui, Wang, Zhaohai, Hu, Minggen, Song, Jianxun, Yang, Penghui, Liu, Rong

“…[Display omitted] •Suppressing eEF2K in hepatocellular carcinoma led to increased NK cell infiltration and activity.•Inhibition of eEF2K expression in…”
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The breadth of concomitant virological features in a family cluster outbreak of COVID‐19 pneumonia by Lei, Guanglin, Meng, Fanping, Wang, Cheng, Yan, Jin, Sun, Fang, Shi, Lei, Li, Wengang, Luan, Junqing, Wang, Siyu, Yang, Penghui

“…An outbreak of a novel coronavirus disease (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) had emerged in 2019 and rapidly…”
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Long Stress Induced Non-Coding Transcripts 5 (LSINCT5) Promotes Hepatocellular Carcinoma Progression Through Interaction with High-Mobility Group AT-hook 2 and MiR-4516 by Li, Ou, Li, Zhizhen, Tang, Qinghe, Li, Yesheng, Yuan, Shengxian, Shen, Yang, Zhang, Zhenhua, Li, Nianfeng, Chu, Kaijian, Lei, Guanglin

“…BACKGROUND Long non-coding RNAs (lncRNAs) have been implicated in various human cancer types. However, the underlying mechanisms involved in hepatocellular…”
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Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes by Sun, Fang, Lei, Guanglin, Tian, Chongyu, Bai, Zhifang, Bai, Changqing, Li, Yufeng, Deng, Zhuoya, Yang, Hao, Li, Cong, Zhao, Zhongpeng, Niu, Yan, Yang, Penghui

“…Human metapneumovirus (HMPV) is a leading cause of acute respiratory tract infections in infants and children. Currently, no approved HMPV vaccine is…”
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Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus by Yang, Zhao, Shi, Mengran, Liang, Youfeng, Zhang, Fuhan, Li, Cong, Lu, Yinying, Yin, Taian, Wang, Zhaohai, Li, Yongchao, Hao, Mingxuan, Guo, Rui, Yang, Hao, Lei, Guanglin, Sun, Fang, Zhang, Yu, Deng, Zhuoya, Tian, Yuying, Yu, Linxiang, Bai, Changqing, Wang, Lei, Wan, Chuanxing, Wang, Haifeng, Yang, Penghui

“…Background Three-dimensional (3D) chromatin architecture frequently altered in cancer. However, its changes during the pathogenesis of hepatocellular carcinoma…”
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SET domain containing 1B gene is mutated in primary hepatic neuroendocrine tumors by Yang, Penghui, Huang, Xuanlin, Lai, Chengcai, Li, Lin, Li, Tieling, Huang, Peide, Ouyang, Songying, Yan, Jin, Cheng, Sijie, Lei, Guanglin, Wang, Zhaohai, Yu, Linxiang, Hong, Zhixian, Li, Ruisheng, Dong, Hui, Wang, Cheng, Yu, Yinghao, Wang, Xuan, Li, Xianghong, Wang, Liming, Lv, Fudong, Yin, Ye, Yang, Huanming, Song, Jianxun, Gao, Qiang, Wang, Xiliang, Zhang, Shaogeng

“…Primary hepatic neuroendocrine tumors (PHNETs) are extremely rare NETs originating from the liver. These tumors are associated with heterogeneous prognosis,…”
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Serum Exosome-Derived microRNA-193a-5p and miR-381-3p Regulate Adenosine 5'-Monophosphate-Activated Protein Kinase/Transforming Growth Factor Beta/Smad2/3 Signaling Pathway and Promote Fibrogenesis by Wang, Sihao, Chen, Yan, Lei, Guanglin, Ma, Xuemei, An, Linjing, Wang, Han, Song, Zheng, Lin, Li, He, Quanwei, Xu, Ran, Zhan, Xiaoyan, Bai, Zhaofang, Yang, Yongping

“…Liver fibrosis results from chronic liver injury and inflammation, often leading to cirrhosis, liver failure, portal hypertension, and hepatocellular…”
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