Search Results - "Guang-Ming Lu"

Filamentation modulates allosteric regulation of PRPS by Hu, Huan-Huan, Lu, Guang-Ming, Chang, Chia-Chun, Li, Yilan, Zhong, Jiale, Guo, Chen-Jun, Zhou, Xian, Yin, Boqi, Zhang, Tianyi, Liu, Ji-Long

“…Phosphoribosyl pyrophosphate (PRPP) is a key intermediate in the biosynthesis of purine and pyrimidine nucleotides, histidine, tryptophan, and cofactors NAD…”
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Structural basis of dynamic P5CS filaments by Zhong, Jiale, Guo, Chen-Jun, Zhou, Xian, Chang, Chia-Chun, Yin, Boqi, Zhang, Tianyi, Hu, Huan-Huan, Lu, Guang-Ming, Liu, Ji-Long

“…The bifunctional enzyme Δ -pyrroline-5-carboxylate synthase (P5CS) is vital to the synthesis of proline and ornithine, playing an essential role in human…”
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Structural basis of human PRPS2 filaments by Lu, Guang-Ming, Hu, Huan-Huan, Chang, Chia-Chun, Zhong, Jiale, Zhou, Xian, Guo, Chen-Jun, Zhang, Tianyi, Li, Yi-Lan, Yin, Boqi, Liu, Ji-Long

“…PRPP synthase (PRPS) transfers the pyrophosphate groups from ATP to ribose-5-phosphate to produce 5-phosphate ribose-1-pyrophosphate (PRPP), a key intermediate…”
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Design, synthesis and biological evaluation of novel quinazoline derivatives as potential NF-κb inhibitors by Pan, Jing, Ma, Long, Tang, Yu-Xia, Tian, Ying, Lin, Yi-Hang, Zhang, Long-Jiang, Gao, Feng, Lu, Guang-Ming

“…A series of novel 4-aminoquinazoline derivatives were designed, synthesized and biological properties on nuclear factor-kappaB (NF-κb) pathway inhibitory and…”
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Reproducibility of image-based computational models of intracranial aneurysm: a comparison between 3D rotational angiography, CT angiography and MR angiography by Ren, Yuan, Chen, Guo-Zhong, Liu, Zhen, Cai, Yan, Lu, Guang-Ming, Li, Zhi-Yong

“…Reconstruction of patient-specific biomechanical model of intracranial aneurysm has been based on different imaging modalities. However, different imaging…”
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Multimodality magnetic resonance imaging in hepatic encephalopathy: An update by Zhang, Xiao-Dong, Zhang, Long-Jiang, Wu, Sheng-Yong, Lu, Guang-Ming

“…Hepatic encephalopathy(HE) is a neuropsychiatric complication of cirrhosis or acute liver failure. Currently, HE is regarded as a continuous cognitive…”
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Shared and specific patterns of structural and functional thalamo-frontal disturbances in manic and euthymic pediatric bipolar disorder by Guo, Yi-Bing, Gao, Wei-Jia, Long, Zhi-Liang, Cao, Wei-Fang, Cui, Dong, Guo, Yong-Xin, Jiao, Qing, Qiu, Jian-Feng, Su, Lin-Yan, Lu, Guang-Ming

“…Bipolar disorder (BD) is clinically defined by alternating depressive and manic episodes with a separated period of euthymia. Thalamo-frontal loop plays vital…”
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Long-and short-range functional connectivity density alteration in non-alcoholic cirrhotic patients one month after liver transplantation: A resting-state fMRI study by Zhang, Xiao-Dong, Cheng, Yue, Poon, Colin S, Qi, Rongfeng, Xu, Qiang, Chen, Hui-Juan, Kong, Xiang, Lu, Guang-Ming, Shen, Wen, Zhang, Long-Jiang

“…Abstract Purpose To longitudinally evaluate long- and short-range functional connectivity density (FCD) alteration in cirrhotic patients one month after liver…”
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Subnetwork mining on functional connectivity network for classification of minimal hepatic encephalopathy by Zhang, Daoqiang, Tu, Liyang, Zhang, Long-Jiang, Jie, Biao, Lu, Guang-Ming

“…Hepatic encephalopathy (HE), as a complication of cirrhosis, is a serious brain disease, which may lead to death. Accurate diagnosis of HE and its intermediate…”
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Coronavirus Disease 2019 (COVID-19): A Perspective from China by Zu, Zi Yue, Jiang, Meng Di, Xu, Peng Peng, Chen, Wen, Ni, Qian Qian, Lu, Guang Ming, Zhang, Long Jiang

“…In December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 infection occurred in Wuhan, Hubei Province, China, and spread across China…”
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Comparison of Positron Emission Tomography Using 2-[^18F]-fluoro-2-deoxy-D-glucose and 3-deoxy-3-[^18F]-fluorothymidine in Lung Cancer Imaging by Wang, Fu-Li, Tan, Ye-Ying, Gu, Xiang-Min, Li, Tian-Ran, Lu, Guang-Ming, Liu, Gang, Huo, Tian-Long

“…Background： The detection of solitary pulmonary nodules （SPNs） that may potentially develop into a malignant lesion is essential for early clinical…”
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Magnetic Resonance Gd？RGD Imaging Study of Hepatocellular Carcinoma with High and Low Metastatic Potential before and after Human Bone Marrow？derived Mesenchymal Stem Cell Intervention by Li, Tian-Ran, Yu, Ming-Hui, Huang, Xiao-Bin, Yang, Zhi-Jie, Lu, Guang-Ming, Li, Yan-Jun

“…Background： Biotherapy based on human bone marrow-derived mesenchymal stem cells （BMSCs） is currently the focus of research, especially in the field of…”
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Underlying Anatomy and Typing Diagnosis of May-Thurner Syndrome and Clinical Significance: An Observation Based on CT by Ou-Yang, Lin, Lu, Guang-ming

“…STUDY DESIGN.Cross-sectional study. OBJECTIVE.To explore the underlying anatomy of May-Thurner syndrome (MTS) using computed tomography (CT) and discuss its…”
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Infection Control and Management Strategy for COVID-19 in the Radiology Department: Focusing on Experiences from China by Qian Chen, Zi Yue Zu, Meng Di Jiang, Lingquan Lu, Guang Ming Lu, Long Jiang Zhang

“…Coronavirus disease 2019 (COVID-19) is a new infectious disease rapidly spreading around the world, raising global public health concerns. Radiological…”
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A deep learning approach to characterize 2019 coronavirus disease (COVID-19) pneumonia in chest CT images by Ni, Qianqian, Sun, Zhi Yuan, Qi, Li, Chen, Wen, Yang, Yi, Wang, Li, Zhang, Xinyuan, Yang, Liu, Fang, Yi, Xing, Zijian, Zhou, Zhen, Yu, Yizhou, Lu, Guang Ming, Zhang, Long Jiang

“…Objectives To utilize a deep learning model for automatic detection of abnormalities in chest CT images from COVID-19 patients and compare its quantitative…”
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128-slice acceletated-pitch dual energy CT angiography of the head and neck: comparison of different low contrast medium volumes by Chen, Yu, Xue, Huadan, Jin, Zheng-yu, Zhang, Jie, Sun, Hao, Wang, Xuan, Zhang, Zhu-hua, Zhang, Da-ming, Lu, Guang-ming, Zhang, Zhao-qi, Schoepf, U Joseph, Bucher, Andreas M, Wolla, Christopher D, Wang, Yun

“…Our study aims to evaluate the image quality and feasibility of 128-slice dual-energy CTA (DE-CTA) for supra-aortic arteries using reduced amounts of contrast…”
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Radiation Optimized Dual-source Dual-energy Computed Tomography Pulmonary Angiography by Li, Xie, MS, Chen, Guo Zhong, MS, Zhao, Yan E., MD, Schoepf, U. Joseph, MD, Albrecht, Moritz H., MD, Bickford, Matthew W., MD, Gu, Hai Feng, BA, Zhang, Long Jiang, MD, PhD, Lu, Guang Ming, MD

“…Objectives This study aimed to intra-individually and inter-individually compare image quality, radiation dose, and diagnostic accuracy of dual-source…”
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Automatic bone removal dual-energy CT angiography for the evaluation of intracranial aneurysms by Zhang, Long-Jiang, Wu, Sheng-Yong, Poon, Colin S, Zhao, Yan-E, Chai, Xue, Zhou, Chang-Sheng, Lu, Guang-Ming

“…To evaluate the diagnostic accuracy of dual-energy computed tomographic angiography (DE-CTA) in the detection of intracranial aneurysms and to determine…”
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Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging by Li, Hui-Jie, Hou, Xiao-Hui, Liu, Han-Hui, Yue, Chun-Lin, Lu, Guang-Ming, Zuo, Xi-Nian

“…Normal aging is associated with cognitive decline and underlying brain dysfunction. Previous studies concentrated less on brain network changes at a systems…”
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Structural basis for ligand binding modes of CTP synthase by Zhou, Xian, Guo, Chen-Jun, Chang, Chia-Chun, Zhong, Jiale, Hu, Huan-Huan, Lu, Guang-Ming, Liu, Ji-Long

“…Cytidine triphosphate synthase (CTPS), which comprises an ammonia ligase domain and a glutamine amidotransferase domain, catalyzes the final step of de novo…”
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