Search Results - "Guan, Youyan"
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Urologic cancer in China
Published in Japanese journal of clinical oncology (01-06-2016)“…Cancer remains to be the second most common cause of death, and its incidence and mortality rates are increasing in China. According to the 2015 National…”
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2
Research Advances in Nucleic Acid Delivery System for Rheumatoid Arthritis Therapy
Published in Pharmaceutics (01-04-2023)“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects the lives of nearly 1% of the total population worldwide. With the…”
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Development of Novel Paclitaxel-Loaded ZIF-8 Metal-Organic Framework Nanoparticles Modified with Peptide Dimers and an Evaluation of Its Inhibitory Effect against Prostate Cancer Cells
Published in Pharmaceutics (01-07-2023)“…Prostate cancer (PC) is one of the common malignant tumors of the male genitourinary system. Here, we constructed PTX@ZIF-8, which is a…”
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Copy number variation of urine exfoliated cells by low-coverage whole genome sequencing for diagnosis of prostate adenocarcinoma: a prospective cohort study
Published in BMC medical genomics (05-05-2022)“…Non-invasive, especially the urine-based diagnosis of prostate cancer (PCa) remains challenging. Although prostate cancer antigen (PSA) is widely used in…”
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Development and Evaluation of a PSMA-Targeted Nanosystem Co-Packaging Docetaxel and Androgen Receptor siRNA for Castration-Resistant Prostate Cancer Treatment
Published in Pharmaceutics (29-04-2022)“…Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) during androgen deprivation therapy (ADR) in early stages of prostate cancer. Thus,…”
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Development of Mitomycin C-Loaded Nanoparticles Prepared Using the Micellar Assembly Driven by the Combined Effect of Hydrogen Bonding and π-π Stacking and Its Therapeutic Application in Bladder Cancer
Published in Pharmaceutics (25-10-2021)“…Micelle is mainly used for drug delivery and is prepared from amphiphilic block copolymers. It can be formed into an obvious core-shell structure that can…”
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Deaths and adverse events from adjuvant therapy with immune checkpoint inhibitors in solid malignant tumors: A systematic review and network meta‐analysis
Published in Cancer innovation (Print) (01-12-2022)“…Background By prolonging overall survival and reducing disease recurrence rates, immune checkpoint inhibitors (ICIs) are an emerging adjuvant therapy option…”
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Neoadjuvant Chemotherapy-Guided Bladder-Sparing Treatment for Muscle-Invasive Bladder Cancer: Results of a Pilot Phase II Study
Published in Cancer research and treatment (01-10-2021)“…Reduced quality of life after cystectomy has made bladder preservation a popular research topic for muscle-invasive bladder cancer (MIBC). Previous research…”
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Improving glioblastoma therapeutic outcomes via doxorubicin-loaded nanomicelles modified with borneol
Published in International journal of pharmaceutics (15-08-2019)“…Borneol (BO) was firstly conjugated with DSPE-PEG2000-COOH to synthesize a novel carrier DSPE-PEG2000-BO to enhance the delivery of doxorubicin (DOX) into…”
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PD09-01 THE TOLERABILITY AND EFFICACY OF BCG ADMINISTRATION AFTER RECURRENCE IN BLADDER-PRESERVING THERAPY FOR MUSCLE-INVASIVE BLADDER CANCER
Published in The Journal of urology (01-04-2023)Get full text
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Enhancing anti-melanoma outcomes in mice using novel chitooligosaccharide nanoparticles loaded with therapeutic survivin-targeted siRNA
Published in European journal of pharmaceutical sciences (01-03-2021)“…Melanoma anti-tumor therapy remains a challenge. SiRNA-based therapies provide a powerful means, but limitations remain in its pharmaceutical applications…”
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Serum IgG: A potential biomarker for predicting the efficacy of systemic therapy in metastatic renal cell carcinoma
Published in Journal of clinical oncology (01-02-2024)“…442 Background: Immunotherapy-tyrosine kinase inhibitor (IO-TKI) and tyrosine kinase inhibitor (TKI) are the main treatment strategies that have significantly…”
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Neoadjuvant combined chemotherapy and immunotherapy for upper tract urothelial carcinoma: Preliminary results from a phase II study
Published in Journal of clinical oncology (01-02-2024)“…636 Background: Upper Tract Urothelial Carcinoma (UTUC) presents a challenging prognosis even after Radical Nephroureterectomy (RNU), and postoperative renal…”
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Transmembrane Transporter Sema3D Serves as a Tumor Suppressor in Localized Clear Cell Renal Cell Carcinoma
Published in Journal of oncology (30-06-2022)“…Background. The transmembrane transporter Sema3D is a vital molecule involved in axon guidance and carcinogenesis of variant malignancies. However, the…”
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Abstract 2296: A multicenter, prospective evaluation of urine-based ctDNA assay for urinary cancers diagnosis
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: There is still some limitations for the diagnosis of urinary cancers, such as the invasiveness of cystoscopy and ureteroscopy, the…”
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Dynamic Changes in Serum Immunoglobulin G Predict Clinical Response and Prognosis in Metastatic Clear-cell Renal Cell Carcinoma
Published in European urology open science (Online) (01-12-2024)“…Changes in serum immunoglobulin G levels after systemic treatment could be a reliable predictor of therapeutic efficacy and prognosis in patients with…”
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Reninoma coexisting with adrenal adenoma during pregnancy: A case report
Published in Oncology letters (01-05-2017)“…Reninoma is a rare form of secondary hypertension. The present study reported a case of reninoma that coexisted with an adrenal adenoma in a young female with…”
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