Search Results - "Guan, Yaqun"
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Ancestral Origins and Genetic History of Tibetan Highlanders
Published in American journal of human genetics (01-09-2016)“…The origin of Tibetans remains one of the most contentious puzzles in history, anthropology, and genetics. Analyses of deeply sequenced (30×–60×) genomes of 38…”
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Adenovirus type 36 regulates adipose stem cell differentiation and glucolipid metabolism through the PI3K/Akt/FoxO1/PPARγ signaling pathway
Published in Lipids in health and disease (21-03-2019)“…This study aims to investigate the molecular mechanism of Adenovirus type 36 (Ad36) in adipocyte differentiation and glucolipid metabolism. Rat obesity model…”
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Investigation of tick-borne bacterial microorganisms in Haemaphysalis ticks from Hebei, Shandong, and Qinghai provinces, China
Published in Ticks and tick-borne diseases (01-03-2024)“…Tick-borne microorganisms in many tick species and many areas of China are still not thoroughly investigated. In this study, 224 ticks including two species…”
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The Effects of Tangning Ziyabitusi on Gut Microbiota and T lymphocyte Subsets in Impaired Glucose Regulation Rats
Published in Frontiers in bioscience (Landmark. Print) (30-09-2022)“…BACKGROUNDImpaired glucose regulation (IGR) represents the prediabetic state and is associated with gut microbiota (GM) dysbiosis and chronic inflammation…”
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Detection of Bartonella in kissing bugs Triatoma rubrofasciata collected from Huizhou City, South China
Published in New microbes and new infections (01-09-2023)“…The blood-feeding behavior of kissing bugs (subfamily Triatominae, family Reduviidae, order Hemiptera) means they are potential vectors of multiple humans…”
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LIMA1 links the E3 ubiquitin ligase RNF40 to lipid metabolism
Published in Cell death discovery (22-06-2024)“…LIMA1 is a LIM domain and Actin binding 1 protein that acts as a skeleton protein to promote cholesterol absorption, which makes it an ideal target for…”
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The complete mitochondrial genome of Fannia scalaris (Diptera: Muscidae)
Published in Mitochondrial DNA. Part B. Resources (03-06-2021)“…Fannia scalaris (Fabricius, 1794) is closely related to human life in ecological habits, which can lead to health concerns since they feed on various…”
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EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects
Published in Human genetics (01-01-2016)“…An adaptive variant of human Ectodysplasin receptor, EDARV370A , had undergone strong positive selection in East Asia. In mice and humans, EDARV370A was found…”
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Characteristics of dental morphology in the Xinjiang Uyghurs and correlation with the EDARV370A variant
Published in Science China. Life sciences (01-05-2014)“…Teeth are one of the most important materials for anthropological studies because they are likely to be preserved in ancient remains.While the frequencies of…”
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Staufen1 unwinds the secondary structure and facilitates the translation of fatty acid binding protein 4 mRNA during adipogenesis
Published in Adipocyte (01-01-2021)“…Adipogenesis is regulated by genetic interactions, in which post-transcriptional regulation plays an important role. Staufen double-stranded RNA binding…”
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Activation of liver X receptor attenuates endothelin-1 expression in vascular endothelial cells
Published in The international journal of biochemistry & cell biology (01-12-2012)“…► This is the first evidence that LXR activation downregulates ET-1 expression in the endothelium. ► Transcriptional activity of AP-1 and NF-κB was one of the…”
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Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait
Published in Journal of genetics and genomics (20-12-2016)“…Petaloid toenail, or accessory nail of the fifth toe, is a physical trait characterized by the presence of an additional tiny toenail on the small toe. Since…”
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Differential expression of microRNAs in serum exosomes of obese and non-obese mice and analysis of their function
Published in Gene (15-11-2024)“…•In this study, serum exosomes from obese and non-obese mice were sequenced for the first time, and several differentially expressed microRNAs that may be…”
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Effect of lncRNA HOXA11-AS1 on adipocyte differentiation in human adipose-derived stem cells
Published in Biochemical and biophysical research communications (08-01-2018)“…To determine the role of lncRNA HOXA11-AS1 on adipocyte differentiation. Human adipose-derived stem cells (hADSCs) were isolated from adipose tissues of…”
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Comparative Genomic and Transcriptomic Analyses Reveal the Impacts of Genetic Admixture in Kazaks, Uyghurs, and Huis
Published in Molecular biology and evolution (04-03-2023)“…Abstract Population admixture results in the combinations of genetic components derived from distinct ancestral populations, which may impact diversity at the…”
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Ancestral Origins and Admixture History of Kazakhs
Published in Molecular biology and evolution (03-07-2024)“…Abstract Kazakh people, like many other populations that settled in Central Asia, demonstrate an array of mixed anthropological features of East Eurasian (EEA)…”
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Investigation of adipocyte differentiation based on proteomics and intact N-glycopeptide modificationomics
Published in Biochimica et biophysica acta. Proteins and proteomics (01-01-2025)“…To investigate the role of N-glycosylation modification of proteins in adipocyte differentiation during the adipogenic process. SVF cells and adipocytes were…”
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HTR1A Gene Polymorphism in Type 2 Diabetes Mellitus Comorbid with Major Depressive Disorder in a Chinese Population
Published in Diabetes, metabolic syndrome and obesity (31-05-2022)“…Major depressive disorder is a frequent mental illness, which is common in patients with type 2 diabetes. Type 2 diabetes comorbid with depression has a worse…”
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Post-zygotic Point Mutations Are an Underrecognized Source of De Novo Genomic Variation
Published in American journal of human genetics (02-07-2015)“…De novo mutations are recognized both as an important source of genetic variation and as a prominent cause of sporadic disease in humans. Mutations identified…”
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Ad36 promotes differentiation of hADSCs into brown adipocytes by up-regulating LncRNA ROR
Published in Life sciences (1973) (15-01-2021)“…This study is to investigate the role of adenovirus type 36 (Ad36) in inducing differentiation of human adipose-derived stem cells (hADSCs) into brown…”
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