Search Results - "Guan, Xiuwen"

Recent advances in selective photothermal therapy of tumor by Zhao, Liping, Zhang, Xu, Wang, Xiaoxia, Guan, Xiuwen, Zhang, Weifeng, Ma, Jinlong

“…Photothermal therapy (PTT), which converts light energy to heat energy, has become a new research hotspot in cancer treatment. Although researchers have…”
Get full text

The relationship between statins and breast cancer prognosis varies by statin type and exposure time: a meta-analysis by Liu, Binliang, Yi, Zongbi, Guan, Xiuwen, Zeng, Yi-Xin, Ma, Fei

“…Purpose Breast cancer is the most common cancer in females and the leading cause of death worldwide. The effects of statins on breast cancer prognosis have…”
Get full text

Antibody-drug conjugates in HER2-positive breast cancer by Li, Lixi, Zhang, Di, Liu, Binliang, Lv, Dan, Zhai, Jingtong, Guan, Xiuwen, Yi, Zongbi, Ma, Fei

“…Antibody-drug conjugates (ADCs) combine the high specificity of monoclonal antibodies with the high anti-tumor activity of small molecular cytotoxic payloads…”
Get full text

In Real Life, Low-Level HER2 Expression May Be Associated With Better Outcome in HER2-Negative Breast Cancer: A Study of the National Cancer Center, China by Li, Yiqun, Abudureheiyimu, Nilupai, Mo, Hongnan, Guan, Xiuwen, Lin, Shaoyan, Wang, Zijing, Chen, Yimeng, Chen, Shanshan, Li, Qiao, Cai, Ruigang, Wang, Jiayu, Luo, Yang, Fan, Ying, Yuan, Peng, Zhang, Pin, Li, Qing, Ma, Fei, Xu, Binghe

“…To characterize the clinical and pathological features and survival of patients with human epidermal growth factor receptor 2 (HER2)-low breast cancer in…”
Get full text

Clinicopathological characteristics and survival outcomes in patients with synchronous lung metastases upon initial metastatic breast cancer diagnosis in Han population by Lin, Shaoyan, Mo, Hongnan, Li, Yiqun, Guan, Xiuwen, Chen, Yimeng, Wang, Zijing, Xu, Binghe

“…We investigated the clinicopathological characteristics and survival of breast cancer lung metastases (BCLM) patients at initial diagnosis of metastatic breast…”
Get full text

Multi-omics fusion analysis models with machine learning predict survival of HER2-negative metastatic breast cancer: a multicenter prospective observational study by Wang, Jiani, Liu, Yuwei, Zhang, Renzhi, Liu, Zhenyu, Yi, Zongbi, Guan, Xiuwen, Zhao, Xinming, Jiang, Jingying, Tian, Jie, Ma, Fei

“…In this study, we characterized the biological parameters extracted from a subset of enrolled patients with human epithelial growth factor receptor-2 (HER2)…”
Get full text

Everolimus in hormone receptor-positive metastatic breast cancer: PIK3CA mutation H1047R was a potential efficacy biomarker in a retrospective study by Yi, Zongbi, Ma, Fei, Liu, Binliang, Guan, Xiuwen, Li, Lixi, Li, Chunxiao, Qian, Haili, Xu, Binghe

“…Everolimus, an inhibitor of mammalian target of rapamycin (mTOR), has been shown to increase the efficacy of endocrine therapies in hormone receptor…”
Get full text

Gut Microbiota Profiling in Patients With HER2-Negative Metastatic Breast Cancer Receiving Metronomic Chemotherapy of Capecitabine Compared to Those Under Conventional Dosage by Guan, Xiuwen, Ma, Fei, Sun, Xiaoying, Li, Chunxiao, Li, Lixi, Liang, Fang, Li, Shaochuan, Yi, Zongbi, Liu, Binliang, Xu, Binghe

“…Purpose: Low-dose metronomic chemotherapy can achieve disease control with reduced toxicity compared to conventional chemotherapy in maximum tolerated dose…”
Get full text

Pooled analyses of randomized controlled trials on pyrotinib plus capecitabine and a rethink of the first‐line options for HER2‐positive relapsed or metastatic breast cancer by Guan, Xiuwen, Ma, Fei, Xu, Binghe

“…This pooled analysis explored the possibility and potential of pyrotinib plus capecitabine as a first‐line regimen in relapsed or metastatic HER2‐positive…”
Get full text

Cooperating minimalist nanovaccine with PD-1 blockade for effective and feasible cancer immunotherapy by Jiang, Mingxia, Zhao, Liping, Cui, Xiaoming, Wu, Xinghan, Zhang, Yuhan, Guan, Xiuwen, Ma, Jinlong, Zhang, Weifen

“…[Display omitted] •Facile antigen/adjuvant co-loaded nanovaccine made by convenient green preparation.•The immunological activity of the antigen and adjuvant…”
Get full text

The molecular tumor burden index as a response evaluation criterion in breast cancer by Yi, Zongbi, Ma, Fei, Rong, Guohua, Liu, Binliang, Guan, Yanfang, Li, Jin, Sun, Xiaoying, Wang, Wenna, Guan, Xiuwen, Mo, Hongnan, Wang, Jiani, Qian, Haili, Xu, Binghe

“…Circulating tumor DNA (ctDNA) is a potential biomarker of prognosis and therapeutic response. We conducted this study to explore the role of the molecular…”
Get full text

Longitudinal HER2 amplification tracked in circulating tumor DNA for therapeutic effect monitoring and prognostic evaluation in patients with breast cancer by Guan, Xiuwen, Liu, Binliang, Niu, Yunyun, Dong, Xin, Zhu, Xia, Li, Chunxiao, Li, Lixi, Yi, Zongbi, Sun, Xiaoying, Chen, Hongyan, Lu, Sijia, Ma, Fei

“…Human epidermal growth factor receptor 2(HER2) status is a crucial predictive factor for prognostic assessment and targeted therapy selection, which may be…”
Get full text

Development and validation of the NCC‐BC‐A scale to assess patient‐reported outcomes for breast cancer patients in China by Ma, Fei, Yan, Xiaoyan, Guan, Xiuwen, Liu, Tianmou

“…Background The commonly used international patient‐reported outcome scales for breast cancer were developed before the advent of multiple targeted therapies…”
Get full text

Genome-wide chromosomal instability by cell-free DNA sequencing predicts survival in patients with metastatic breast cancer by Mo, Hongnan, Wang, Xiaobing, Ma, Fei, Qian, Ziliang, Sun, Xiaoying, Yi, Zongbi, Guan, Xiuwen, Li, Lixi, Liu, Binliang, Xu, Binghe

“…Genome-wide chromosomal instability, instead of specific somatic mutations or copy-number alterations in selected genes, is a significant property of cancer…”
Get full text

A nanosystem of copper(II)-disulfiram for cancer treatment with high efficacy and few side effects by ZHAO, Liping, WANG, Xiaoxia, JIANG, Mingxia, WU, Xinghan, ZHANG, Mogen, GUAN, Xiuwen, MA, Jinlong, ZHANG, Weifen

“…Developing chemotherapy drugs with high efficacy and few side effects has been a bottleneck problem that requires an efficient solution. The active cancer…”
Get full text

Fabrication and Characterization of Chitosan/Poly(Lactic-Co-glycolic Acid) Core-Shell Nanoparticles by Coaxial Electrospray Technology for Dual Delivery of Natamycin and Clotrimazole by Cui, Xiaoming, Li, Xiaoli, Xu, Zhilu, Guan, Xiuwen, Ma, Jinlong, Ding, Dejun, Zhang, Weifen

“…Natamycin (NAT) is the drug of choice for the treatment of fungal keratitis (FK). However, its inherent shortcomings, such as poor solubility, high dosing…”
Get full text

The prognostic and therapeutic implications of circulating tumor cell phenotype detection based on epithelial–mesenchymal transition markers in the first‐line chemotherapy of HER2‐negative metastatic breast cancer by Guan, Xiuwen, Ma, Fei, Li, Chunxiao, Wu, Shiyang, Hu, Shangying, Huang, Jiefen, Sun, Xiaoying, Wang, Jiayu, Luo, Yang, Cai, Ruigang, Fan, Ying, Li, Qiao, Chen, Shanshan, Zhang, Pin, Li, Qing, Xu, Binghe

“…Background Epithelial–mesenchymal transition (EMT) is implicated in the metastatic process and presents a challenge to epithelial cell adhesion molecule‐based…”
Get full text

Safety and efficacy of sirolimus combined with endocrine therapy in patients with advanced hormone receptor-positive breast cancer and the exploration of biomarkers by Yi, Zongbi, Liu, Binliang, Sun, Xiaoying, Rong, Guohua, Wang, Wenna, Li, Hui, Guan, Xiuwen, Li, Lixi, Zhai, Jingtong, Li, Chunxiao, Qian, Haili, Ma, Fei, Xu, Binghe

“…We performed a retrospective study on the efficacy and safety of sirolimus (an mTOR inhibitor) in hormone receptor (HR)-positive advanced breast cancer and…”
Get full text

Synergetic burns treatment by self-adaption release system combined with cold atmospheric plasma by Wang, XiaoXia, Liu, ZhiJun, Zhao, LiPing, Yang, HuiJie, Qin, JiaMin, Zhang, JingQi, Zhao, JiaXuan, Guan, XiuWen, Zhang, WeiFen, Ma, JinLong

“…In the tissue remodeling stage of burns, excessive medical therapy can cause scarring by promoting excessive fibroblast proliferation and collagen deposition…”
Get full text

Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer by Yi, Zongbi, Rong, Guohua, Guan, Yanfang, Li, Jin, Chang, Lianpeng, Li, Hui, Liu, Binliang, Wang, Wenna, Guan, Xiuwen, Ouyang, Quchang, Li, Lixi, Zhai, Jingtong, Li, Chunxiao, Li, Lifeng, Xia, Xuefeng, Yang, Ling, Qian, Haili, Yi, Xin, Xu, Binghe, Ma, Fei

“…Human epidermal growth factor receptor 2 (HER2) protein overexpression or gene amplification is an important predictive biomarker for identifying patients with…”
Get full text