Search Results - "Guan, Wuqiang"
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Generation of neural progenitor cells by chemical cocktails and hypoxia
Published in Cell research (01-06-2014)“…Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts…”
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2
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo
Published in Nature biotechnology (01-05-2022)“…Endocannabinoids (eCBs) are retrograde neuromodulators with important functions in a wide range of physiological processes, but their in vivo dynamics remain…”
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3
Genetically identified amygdala–striatal circuits for valence-specific behaviors
Published in Nature neuroscience (01-11-2021)“…The basolateral amygdala (BLA) plays essential roles in behaviors motivated by stimuli with either positive or negative valence, but how it processes…”
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4
Direct conversion of astrocytes into neuronal cells by drug cocktail
Published in Cell research (01-11-2015)“…Dear Editor, Neurological disorder is one of the greatest threats to public health according to the World Health Organi- zation. Because neurons have little or…”
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5
Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons
Published in eLife (16-07-2024)“…Axo-axonic cells (AACs), also called chandelier cells (ChCs) in the cerebral cortex, are the most distinctive type of GABAergic interneurons described in the…”
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6
Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells
Published in Scientific reports (05-03-2019)“…Glioblastoma (GBM) is the most common and aggressive malignant tumor in adult brain. Even with the current standard therapy including surgical resection…”
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Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules
Published in Stem cell reports (14-03-2017)“…Astrocytes, due to the proximity to neuronal lineage and capability to proliferate, are ideal starting cells to regenerate neurons. Human fetal astrocytes have…”
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8
Graded and pan-neural disease phenotypes of Rett Syndrome linked with dosage of functional MeCP2
Published in Protein & cell (01-08-2021)“…Rett syndrome (RTT) is a progressive neurodevelopmental disorder, mainly caused by mutations in MeCP2 and currently with no cure. We report here that neurons…”
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Author Correction: Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells
Published in Scientific reports (14-02-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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10
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo
Published in Nature biotechnology (01-05-2022)Get full text
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11
Generation of neural progenitor cells by chemical cocktails and hypoxia
Published in Cell research (01-05-2015)“…In the initial published version of this article, an er- ror was made during the assembly of Figure 6C. Figure 6C displays representative images of morphology…”
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12
Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex
Published in eLife (11-12-2017)“…Eye opening, a natural and timed event during animal development, influences cortical circuit assembly and maturation; yet, little is known about its precise…”
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Erratum: Generation of neural progenitor cells by chemical cocktails and hypoxia
Published in Cell research (05-05-2015)“…Correction to: Cell Research (2014) 24:665–679. doi:10.1038/cr.2014.32; published online on 18 March 2014 In the initial published version of this article, an…”
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14
Diverse Roles of Serotonergic Projections to the Basolateral Amygdala
Published in Neuroscience bulletin (01-09-2023)Get full text
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15
Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules
Published in Cell stem cell (06-08-2015)“…Neuronal conversion from human fibroblasts can be induced by lineage-specific transcription factors; however, the introduction of ectopic genes limits the…”
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16
Synaptic Transmission from Somatostatin-expressing Interneurons to Excitatory Neurons Mediated by α5-subunit-containing GABAA Receptors in the Developing Visual Cortex
Published in Neuroscience (21-11-2020)“…•α5-GABAARs are specifically involved in synaptic transmission from SST-INs to PCs.•Weakening of synaptic transmission is mainly mediated by postsynaptic…”
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17
Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons
Published in eLife (16-07-2024)“…Axo-axonic cells (AACs), also called chandelier cells (ChCs) in the cerebral cortex, are the most distinctive type of GABAergic interneurons described in the…”
Get full text
Journal Article -
18
Synaptic Transmission from Somatostatin-expressing Interneurons to Excitatory Neurons Mediated by α5-subunit-containing GABA A Receptors in the Developing Visual Cortex
Published in Neuroscience (21-11-2020)“…Dendrite-targeting somatostatin-expressing interneurons (SST-INs) powerfully control signal integration and synaptic plasticity in pyramidal dendrites during…”
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19
Cerebellar stem cells do not produce neurons and astrocytes in adult mouse
Published in Biochemical and biophysical research communications (18-07-2014)“…•No new neurons and astrocytes are generated in adult mouse cerebellum.•Very few mash1+ or nestin+ stem cells exist, and most of them are quiescent.•Cell…”
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20
Calretinin-positive L5a pyramidal neurons in the development of the paralemniscal pathway in the barrel cortex
Published in Molecular brain (18-11-2014)“…The rodent barrel cortex has been established as an ideal model for studying the development and plasticity of a neuronal circuit. The barrel cortex consists…”
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