Search Results - "Guan, Wuqiang"

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  1. 1

    Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

    Published in Cell research (01-06-2014)
    “…Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts…”
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    Journal Article
  2. 2

    A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo by Dong, Ao, He, Kaikai, Dudok, Barna, Farrell, Jordan S., Guan, Wuqiang, Liput, Daniel J., Puhl, Henry L., Cai, Ruyi, Wang, Huan, Duan, Jiali, Albarran, Eddy, Ding, Jun, Lovinger, David M., Li, Bo, Soltesz, Ivan, Li, Yulong

    Published in Nature biotechnology (01-05-2022)
    “…Endocannabinoids (eCBs) are retrograde neuromodulators with important functions in a wide range of physiological processes, but their in vivo dynamics remain…”
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    Journal Article
  3. 3

    Genetically identified amygdala–striatal circuits for valence-specific behaviors by Zhang, Xian, Guan, Wuqiang, Yang, Tao, Furlan, Alessandro, Xiao, Xiong, Yu, Kai, An, Xu, Galbavy, William, Ramakrishnan, Charu, Deisseroth, Karl, Ritola, Kimberly, Hantman, Adam, He, Miao, Josh Huang, Z., Li, Bo

    Published in Nature neuroscience (01-11-2021)
    “…The basolateral amygdala (BLA) plays essential roles in behaviors motivated by stimuli with either positive or negative valence, but how it processes…”
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    Journal Article
  4. 4

    Direct conversion of astrocytes into neuronal cells by drug cocktail by Cheng, Lin, Gao, Longfei, Guan, Wuqiang, Mao, Jianxin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Pei, Gang

    Published in Cell research (01-11-2015)
    “…Dear Editor, Neurological disorder is one of the greatest threats to public health according to the World Health Organi- zation. Because neurons have little or…”
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    Journal Article
  5. 5

    Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons by Raudales, Ricardo, Kim, Gukhan, Kelly, Sean M, Hatfield, Joshua, Guan, Wuqiang, Zhao, Shengli, Paul, Anirban, Qian, Yongjun, Li, Bo, Huang, Z Josh

    Published in eLife (16-07-2024)
    “…Axo-axonic cells (AACs), also called chandelier cells (ChCs) in the cerebral cortex, are the most distinctive type of GABAergic interneurons described in the…”
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    Journal Article
  6. 6

    Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells by Gao, Longfei, Huang, Shichao, Zhang, Hong, Hua, Wei, Xin, Shunmei, Cheng, Lin, Guan, Wuqiang, Yu, Yongchun, Mao, Ying, Pei, Gang

    Published in Scientific reports (05-03-2019)
    “…Glioblastoma (GBM) is the most common and aggressive malignant tumor in adult brain. Even with the current standard therapy including surgical resection…”
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  7. 7

    Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules by Gao, Longfei, Guan, Wuqiang, Wang, Min, Wang, Huihan, Yu, Jiali, Liu, Qing, Qiu, Binlong, Yu, Yongchun, Ping, Yifang, Bian, Xiuwu, Shen, Li, Pei, Gang

    Published in Stem cell reports (14-03-2017)
    “…Astrocytes, due to the proximity to neuronal lineage and capability to proliferate, are ideal starting cells to regenerate neurons. Human fetal astrocytes have…”
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    Journal Article
  8. 8

    Graded and pan-neural disease phenotypes of Rett Syndrome linked with dosage of functional MeCP2 by Chen, Xiaoying, Han, Xu, Blanchi, Bruno, Guan, Wuqiang, Ge, Weihong, Yu, Yong-Chun, Sun, Yi E.

    Published in Protein & cell (01-08-2021)
    “…Rett syndrome (RTT) is a progressive neurodevelopmental disorder, mainly caused by mutations in MeCP2 and currently with no cure. We report here that neurons…”
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    Journal Article
  9. 9

    Author Correction: Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells by Gao, Longfei, Huang, Shichao, Zhang, Hong, Hua, Wei, Xin, Shunmei, Cheng, Lin, Guan, Wuqiang, Yu, Yongchun, Mao, Ying, Pei, Gang

    Published in Scientific reports (14-02-2020)
    “…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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    Journal Article
  10. 10
  11. 11

    Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

    Published in Cell research (01-05-2015)
    “…In the initial published version of this article, an er- ror was made during the assembly of Figure 6C. Figure 6C displays representative images of morphology…”
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    Journal Article
  12. 12

    Eye opening differentially modulates inhibitory synaptic transmission in the developing visual cortex by Guan, Wuqiang, Cao, Jun-Wei, Liu, Lin-Yun, Zhao, Zhi-Hao, Fu, Yinghui, Yu, Yong-Chun

    Published in eLife (11-12-2017)
    “…Eye opening, a natural and timed event during animal development, influences cortical circuit assembly and maturation; yet, little is known about its precise…”
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  13. 13

    Erratum: Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

    Published in Cell research (05-05-2015)
    “…Correction to: Cell Research (2014) 24:665–679. doi:10.1038/cr.2014.32; published online on 18 March 2014 In the initial published version of this article, an…”
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  14. 14
  15. 15

    Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules by Hu, Wenxiang, Qiu, Binlong, Guan, Wuqiang, Wang, Qinying, Wang, Min, Li, Wei, Gao, Longfei, Shen, Lu, Huang, Yin, Xie, Gangcai, Zhao, Hanzhi, Jin, Ying, Tang, Beisha, Yu, Yongchun, Zhao, Jian, Pei, Gang

    Published in Cell stem cell (06-08-2015)
    “…Neuronal conversion from human fibroblasts can be induced by lineage-specific transcription factors; however, the introduction of ectopic genes limits the…”
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    Journal Article
  16. 16

    Synaptic Transmission from Somatostatin-expressing Interneurons to Excitatory Neurons Mediated by α5-subunit-containing GABAA Receptors in the Developing Visual Cortex by Cao, Jun-Wei, Guan, Wuqiang, Yu, Yong-Chun, Fu, Yinghui

    Published in Neuroscience (21-11-2020)
    “…•α5-GABAARs are specifically involved in synaptic transmission from SST-INs to PCs.•Weakening of synaptic transmission is mainly mediated by postsynaptic…”
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    Journal Article
  17. 17

    Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons by Raudales, Ricardo, Kim, Gukhan, Kelly, Sean M, Hatfield, Joshua, Guan, Wuqiang, Zhao, Shengli, Paul, Anirban, Qian, Yongjun, Li, Bo, Huang, Z Josh

    Published in eLife (16-07-2024)
    “…Axo-axonic cells (AACs), also called chandelier cells (ChCs) in the cerebral cortex, are the most distinctive type of GABAergic interneurons described in the…”
    Get full text
    Journal Article
  18. 18

    Synaptic Transmission from Somatostatin-expressing Interneurons to Excitatory Neurons Mediated by α5-subunit-containing GABA A Receptors in the Developing Visual Cortex by Cao, Jun-Wei, Guan, Wuqiang, Yu, Yong-Chun, Fu, Yinghui

    Published in Neuroscience (21-11-2020)
    “…Dendrite-targeting somatostatin-expressing interneurons (SST-INs) powerfully control signal integration and synaptic plasticity in pyramidal dendrites during…”
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    Journal Article
  19. 19

    Cerebellar stem cells do not produce neurons and astrocytes in adult mouse by Su, Xin, Guan, Wuqiang, Yu, Yong-Chun, Fu, Yinghui

    “…•No new neurons and astrocytes are generated in adult mouse cerebellum.•Very few mash1+ or nestin+ stem cells exist, and most of them are quiescent.•Cell…”
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  20. 20

    Calretinin-positive L5a pyramidal neurons in the development of the paralemniscal pathway in the barrel cortex by Liu, Junhua, Liu, Bin, Zhang, XiaoYun, Yu, Baocong, Guan, Wuqiang, Wang, Kun, Yang, Yang, Gong, Yifan, Wu, Xiaojing, Yanagawa, Yuchio, Wu, Shengxi, Zhao, Chunjie

    Published in Molecular brain (18-11-2014)
    “…The rodent barrel cortex has been established as an ideal model for studying the development and plasticity of a neuronal circuit. The barrel cortex consists…”
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    Journal Article