Search Results - "Guan, Shengjiang"

Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways by Wei, Ziheng, Xue, Yurun, Xue, Yucong, Cheng, Jie, Lv, Guoping, Chu, Li, Ma, Zhihong, Guan, Shengjiang

“…Ferulic acid (FA) is a natural polyphenol compound existing in many plants. The purpose of this study was to investigate the effect of FA on non-alcoholic…”
Get full text

Safranal, an active constituent of saffron, ameliorates myocardial ischemia via reduction of oxidative stress and regulation of Ca2+ homeostasis by Xue, Yurun, Jin, Weiyue, Xue, Yucong, Zhang, Yuanyuan, Wang, Hongfang, Zhang, Yixin, Guan, Shengjiang, Chu, Xi, Zhang, Jianping

“…Safranal (SFR) is the major constituent of saffron. The purpose of this study was to observe the effect of SFR on myocardial ischemia induced by isoprenaline…”
Get full text

Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways by Jin, Weiyue, Xue, Yurun, Xue, Yucong, Han, Xue, Song, Qiongtao, Zhang, Jianping, Li, Ziliang, Cheng, Jie, Guan, Shengjiang, Sun, Shijiang, Chu, Li

“…[Display omitted] •Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity.•Tannic acid inhibits NF-κB and activates Nrf2 pathways.•Tannic acid…”
Get full text

Protective mechanisms of 10-gingerol against myocardial ischemia may involve activation of JAK2/STAT3 pathway and regulation of Ca2+ homeostasis by Han, Xue, Qi, Jiaying, Yang, Yakun, Zheng, Bin, Liu, Miaomiao, Liu, Yu, Li, Li, Guan, Shengjiang, Jia, Qingzhong, Chu, Li

“…10-Gingerol (10-Gin), an active ingredient extracted from ginger, has been reported to have beneficial effects on the cardiovascular system. However, its…”
Get full text

Mechanisms underlying the cardio-protection of total ginsenosides against myocardial ischemia in rats in vivo and in vitro: Possible involvement of L-type Ca2+ channels, contractility and Ca2+ homeostasis by Han, Xue, Li, Mengying, Zhao, Zhifeng, Zhang, Yuanyuan, Zhang, Jianping, Zhang, Xuan, Zhang, Ying, Guan, Shengjiang, Chu, Li

“…Here we aimed to observe the effects of total ginsenosides (TG) against isoproterenol (ISO) induced myocardial ischemia (MI) and to explore its underlying…”
Get full text

Protective Effects of 6-Gingerol on Cardiotoxicity Induced by Arsenic Trioxide Through AMPK/SIRT1/PGC-1α Signaling Pathway by Han, Xue, Yang, Yakun, Zhang, Muqing, Chu, Xi, Zheng, Bin, Liu, Chenxu, Xue, Yucong, Guan, Shengjiang, Sun, Shijiang, Jia, Qingzhong

“…Arsenic trioxide (As O ) induced cardiotoxicity to limit the clinical applications of the effective anticancer agent. 6-Gingerol (6G) is the main active…”
Get full text

Protective effect of baicalin against arsenic trioxide-induced acute hepatic injury in mice through JAK2/STAT3 signaling pathway by He, Qianqian, Sun, Xiaoqi, Zhang, Muqing, Chu, Li, Zhao, Yang, Wu, Yongchao, Zhang, Jianping, Han, Xue, Guan, Shengjiang, Ding, Chao

“…Baicalin (BA) is a kind of flavonoid that is isolated from Scutellaria baicalensis Georgi, which has been verified to have hepatoprotective effects in some…”
Get full text

Cardioprotective effects of glycyrrhizic acid involve inhibition of calcium influx via L-type calcium channels and myocardial contraction in rats by Li, Mengying, Wen, Zishuai, Xue, Yurun, Han, Xue, Ma, Donglai, Ma, Zhihong, Wu, Zhonglin, Guan, Shengjiang, Sun, Shijiang, Chu, Li

“…Glycyrrhizic acid (GA) is one of the main active components in licorice and has often been reported to have cardioprotective effects. However, the underlying…”
Get full text

6-Gingerol attenuates arsenic trioxide-induced liver injury by inhibiting pyroptosis and ROS-NLRP3 inflammatory signaling pathway: Based on network pharmacology analysis and experiment verification by Wu, Yongchao, Sun, Xiaoqi, Li, Haoying, Chu, Xi, Xue, Yucong, Qi, Jiaying, Jia, Qingzhong, Han, Xue, Chu, Li, Guan, Shengjiang, Wang, Xiangting

“…[Display omitted] •6-gingerol can attenuate arsenic trioxide (ATO)-induced hepatocyte pyroptosis.•The ROS-NLRP3 pyroptosis pathway may participate in…”
Get full text

Effects of Total Flavones from Acanthopanax senticosus on L‐type Calcium Channels, Calcium Transient and Contractility in Rat Ventricular Myocytes by Guan, Shengjiang, Ma, Juanjuan, Chu, Xi, Gao, Yonggang, Zhang, Ying, Zhang, Xuan, Zhang, Fenghua, Liu, Zhenyi, Zhang, Jianping, Chu, Li

“…Acanthopanax senticosus (Rupr. et Maxim.) Harms (AS), a traditional herbal medicine, has been widely used to treat ischemic heart disease. However, the…”
Get full text

Danshen (Salvia miltiorrhiza) injection suppresses kidney injury induced by iron overload in mice by Guan, Shengjiang, Ma, Juanjuan, Zhang, Ying, Gao, Yonggang, Zhang, Yuanyuan, Zhang, Xuan, Wang, Na, Xie, Yun, Wang, Jiangyan, Zhang, Jianping, Chu, Li

“…Excessive iron can accumulate in the kidney and induce tissue damage. Danshen (Salvia miltiorrhiza) injection is a traditional Chinese medicinal preparation…”
Get full text

Evaluation of the relationship between polymorphisms in CYP2C19 and the single‐dose pharmacokinetics of omeprazole in healthy Chinese volunteers: A multicenter study by Zhou, Shuang, Xie, Ran, Zhang, Xiaodan, He, Xu, Huang, Jie, Jungang, Yin, Liao, Man, Ding, Ying, Yang, Dandan, Liu, Ying, Zhang, Qian, Yang, Guoping, Liu, Fang, Guan, Shengjiang, He, Qing, Lou, Honggang, Gong, Fengyun, Meng, Xianmin, Xiang, Qian, Zhao, Xia, Cui, Yimin

“…The aim of this study was to evaluate the relationship between polymorphisms in CYP2C19 and the single‐dose pharmacokinetics (PKs) of omeprazole in healthy…”
Get full text

RhoA/ROCK may involve in cardiac hypertrophy induced by experimental hyperthyroidism by Na, Wang, Peng, Guan, Jianping, Zhang, Yanzhong, Chang, Shengjiang, Guan, Li, Chu

“…In this study, the role of the RhoA/Rho-kinase (RhoA/ROCK)-signaling pathway in cardiovascular dysfunction associated with hyperthyroidism was examined with…”
Get full text

Luteolin targets the AGE-RAGE signaling to mitigate inflammation and ferroptosis in chronic atrophic gastritis by Zhang, Nailin, Chen, Pingping, Liang, Xiaoyan, Sun, Jianhui, Liu, Qiquan, Guan, Shengjiang, Wang, Qiao

“…Chronic atrophic gastritis (CAG) is a chronic inflammatory disease and precancerous lesion in stomach cancer. Abnormal activation cellular ferroptosis further…”
Get full text

Icotinib: efficacy in different solid tumors and gene mutations by Zhao, Qian, Cheng, Jie, Chen, Pingping, Sun, Jiewei, Guan, Shengjiang

“…Icotinib is a first-generation inhibitor of epidermal growth factor receptor, which has been approved by the Chinese National Medical Products Administration,…”
Get full text

Protective effects and possible mechanism of 6-gingerol against arsenic trioxide-induced nephrotoxicity based on network pharmacological analysis and experimental validation by Han, Xue, Yang, Yakun, Qi, Jiaying, Zhang, Muqing, Xue, Yucong, Chu, Xi, Jia, Qingzhong, Sun, Shijiang, Guan, Shengjiang

“…[Display omitted] •Nephrotoxicity induced by the arsenic trioxide is often overlooked and the underlying mechanisms remain poorly understood.•Network…”
Get full text

Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis by Jin, Weiyue, Zhang, Yuanyuan, Xue, Yurun, Han, Xue, Zhang, Xuan, Ma, Zhihong, Sun, Shijiang, Chu, Xi, Cheng, Jie, Guan, Shengjiang, Li, Ziliang, Chu, Li

“…Crocin is isolated from saffron and has multiple activities. There are many reports on its beneficial effects for cardiovascular disease, but crocin’s effects…”
Get full text

Investigation of the ameliorative effects of baicalin against arsenic trioxide-induced cardiac toxicity in mice by Sun, Xiaoqi, Wang, Xiaotian, He, Qianqian, Zhang, Muqing, Chu, Li, Zhao, Yang, Wu, Yongchao, Zhang, Jianping, Han, Xue, Chu, Xi, Wu, Zhonglin, Guan, Shengjiang

“…•Baicalin ameliorates oxidative stress, inflammation and apoptosis in the heart.•Baicalin activates the expression of TLR4/NF-κB signaling pathway.•Baicalin…”
Get full text

Chemical Characteristics and Comparison of Schizonepetae Herba and Schizonepetae Herba Carbonisata by Combination of GC-MS and UHPLC-MS Strategies by Xiaoying, Ding, Hao, Shenghui, Li, Hengyang, Wang, Tao, Li, Wenjie, Guan, Shengjiang, Zheng, Yuguang, Guo, Long, Zhang, Dan

“…Schizonepetae Herba (SH, Jingjie) and Schizonepetae Herba Carbonisata (SHC, Jingjie Tan) are two different forms of the same herbal material, with SHC being…”
Get full text

Liquiritin Protects Against Cardiac Fibrosis After Myocardial Infarction by Inhibiting CCL5 Expression and the NF-[KAPPA]B Signaling Pathway by Han, Xue, Yang, Yakun, Zhang, Muqing, Li, Li, Xue, Yucong, Jia, Qingzhong, Wang, Xiangting, Guan, Shengjiang

“…Purpose: Despite significant advances in interventional treatment, myocardial infarction (MI) and subsequent cardiac fibrosis remain major causes of high…”
Get full text