Search Results - "Guan, Liying"

Prevalence, awareness, treatment and control of diabetes mellitus among middle-aged and elderly people in a rural Chinese population: A cross-sectional study by Wang, Qian, Zhang, Xu, Fang, Li, Guan, Qingbo, Guan, Liying, Li, Qiu

“…Diabetes mellitus ranks high on the international health agenda as a global pandemic and as a threat to human health and global economies. A total of 10851…”
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The cell cortex-localized protein CHDP-1 is required for dendritic development and transport in C. elegans neurons by Zhao, Ting, Guan, Liying, Ma, Xuehua, Chen, Baohui, Ding, Mei, Zou, Wei

“…Cortical actin, a thin layer of actin network underneath the plasma membranes, plays critical roles in numerous processes, such as cell morphogenesis and…”
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Bioinformatics analysis identifies potential diagnostic signatures for coronary artery disease by Zhang, Dong, Guan, Liying, Li, Xiaoming

“…Background Coronary artery disease (CAD) is the leading cause of mortality worldwide. We aimed to screen out potential gene signatures and construct a…”
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Alleviating chronic ER stress by p38-Ire1-Xbp1 pathway and insulin-associated autophagy in C. elegans neurons by Guan, Liying, Zhan, Zhigao, Yang, Yongzhi, Miao, Yue, Huang, Xun, Ding, Mei

“…ER stress occurs in many physiological and pathological conditions. However, how chronic ER stress is alleviated in specific cells in an intact organism is an…”
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Remnant cholesterol, stronger than triglycerides, is associated with incident non-alcoholic fatty liver disease by Cheng, Yiping, Zhang, Qiang, Li, Haizhen, Zhou, Guangshuai, Shi, Ping, Zhang, Xu, Guan, Liying, Yan, Fang, Xu, Chao

“…Non-alcoholic fatty liver disease (NAFLD) is characterized by excess accumulation of triglycerides within the liver. However, whether the circulating levels of…”
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Continuous positive airway pressure may improve hypertension in patients with obstructive sleep apnea-hypopnea syndrome by inhibiting inflammation and oxidative stress by Wang, Xiaoting, Guan, Liying, Wu, Changzhen, Zhao, Yongjun, Zhao, Gang

“…The work was designed to investigate the effect of continuous positive airway pressure (CPAP) on hypertension in obstructive sleep apnea-hypopnea syndrome…”
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Association between different obesity phenotypes and hypothyroidism: a study based on a longitudinal health management cohort by Wang, Yupeng, Lin, Haiyan, Li, Qihang, Guan, Liying, Zhao, Meng, Zhong, Fang, Liu, Jing, Yuan, Zhongshang, Guo, Honglin, Song, Yongfeng, Gao, Ling, Zhao, Jiajun

“…Purpose Obese individuals have an increased risk of hypothyroidism. This study investigated the sex-specific association between obesity phenotypes and the…”
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Efficacy and Safety of Ningmitai Capsules in Patients with Chronic Epididymitis: A Prospective, Parallel Randomized Controlled Clinical Trial by Jing, Zhang, Liying, Guan, Zhenqing, Wang, Hui, Zhang, Shuai, Liu, Dingqi, Sun, Qiang, Fu, Keqin, Zhang

“…Objectives. To evaluate the efficacy and safety of Ningmitai (NMT) capsules in patients with chronic epididymitis. Methods. This prospective randomized…”
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Systemic Lupus Erythematosus Patients With Related Organic Damage Are at High Risk of Hypothyroidism by Ni, Jiajia, Li, Jingyi, Wang, Yuyao, Guan, Liying, Lin, Haiyan, Zhang, Li, Zhang, Haiqing

“…Purpose The aim of this study included determining the prevalence of hypothyroidism in patients with systemic lupus erythematosus (SLE), clarifying the…”
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Red Blood Cell Count: An Unrecognized Risk Factor for Nonalcoholic Fatty Liver Disease by Zhong, Fang, Guan, Liying, Lin, Haiyan, Zhao, Meng, Qin, Yiming, Li, Qihang, Yuan, Zhongshang, Yang, Guang, Gao, Ling, Zhao, Jiajun

“…Nonalcoholic fatty liver disease (NAFLD) is becoming a global public health challenge. A convenient NAFLD indicator will greatly facilitate risk appraisal and…”
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Interaction effect of obesity and thyroid autoimmunity on the prevalence of hyperthyrotropinaemia by Guo, Xiaoyong, He, Zhao, Shao, Shanshan, Fu, Yilin, Zheng, Dongmei, Liu, Lu, Gao, Ling, Guan, Liying, Zhao, Meng, Zhao, Jiajun

“…Purpose The role of thyroid autoimmunity in the association between obesity and hyperthyrotropinaemia remains unclear. We aimed to assess the relationship…”
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ROS leads to MnSOD upregulation through ERK2 translocation and p53 activation in selenite-induced apoptosis of NB4 cells by Li, Zhushi, Shi, Kejian, Guan, Liying, Cao, Tingming, Jiang, Qian, Yang, Yang, Xu, Caimin

“…Following our previous finding that sodium selenite induces apoptosis in human leukemia NB4 cells, we now show that the expression of the critical antioxidant…”
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Sodium selenite induces apoptosis by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in human acute promyelocytic leukemia NB4 cells by Guan, Liying, Han, Binshe, Li, Zhushi, Hua, Fangyuan, Huang, Fang, Wei, Wei, Yang, Yang, Xu, Caimin

“…Introduction In this study, we delineated the apoptotic signaling pathways activated by sodium selenite in NB4 cells. Materials and methods NB4 cells were…”
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The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions by Guan, Liying, Ma, Xuehua, Zhang, Jingyan, Liu, Jia-Jia, Wang, Yingchun, Ding, Mei

“…Eukaryotic cells extend a variety of surface protrusions to direct cell motility. Formation of protrusions is mediated by coordinated actions between the…”
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Neuronal target identification requires AHA-1-mediated fine-tuning of Wnt signaling in C. elegans by Zhang, Jingyan, Li, Xia, Jevince, Angela R, Guan, Liying, Wang, Jiaming, Hall, David H, Huang, Xun, Ding, Mei

“…Electrical synaptic transmission through gap junctions is a vital mode of intercellular communication in the nervous system. The mechanism by which reciprocal…”
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Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network parmacology and molecular docking by Tianyu, Zhao, Liying, Guan

“…Xuebijing Injection have been found to improve the clinical symptoms of COVID-19 and alleviate disease severity, but the mechanisms are currently unclear. This…”
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P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis by Guan, Liying (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Huang, Fang (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Li, Zhushi (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Han, Bingshe (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Jiang, Qian (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Ren, Yun (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Yang, Yang (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), Xu, Caimin (Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China), E-mail: caiminxu@yahoo.com.cn

“…Selenium, an essential trace element possessing anti-carcinogenic properties, can induce apoptosis in cancer cells. We have previously shown that sodium…”
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Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network pharmacology and molecular docking by Tianyu, Zhao, Liying, Guan

“…Xuebijing Injection have been found to improve the clinical symptoms of COVID-19 and alleviate disease severity, but the mechanisms are currently unclear. This…”
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Differential RUNX1-Isoform Specific Autoregulation of RUNX1 and Regulation of Target Genes (PCTP, MYL9) in Megakaryocytic Cells by Guan, Liying, Voora, Deepak, Myers, Rachel A, Rao, Angara Koneti

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RUNX1 isoforms regulate RUNX1 and target genes differentially in platelets-megakaryocytes: association with clinical cardiovascular events by Guan, Liying, Voora, Deepak, Myers, Rachel, Del Carpio-Cano, Fabiola, Rao, A. Koneti

“…Hematopoietic transcription factor RUNX1 is expressed from proximal P2 and distal P1 promoters to yield isoforms RUNX1 B and C, respectively. The roles of…”
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