Search Results - "Guan, H C"

Link between D1 and D2 Dopamine Receptors is Reduced in Schizophrenia and Huntington Diseased Brain by Seeman, Philip, Niznik, Hyman B., H.-C. Guan, Booth, Gillian, Ulpian, Carla

“…Dopamine receptor types D1 and D2 can oppose or enhance each other's actions for electrical, biochemical, and psychomotor effects. We report a D1-D2…”
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Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: implications for positron emission tomography of the human brain by Seeman, P, Guan, H C, Niznik, H B

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Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes by Asghari, V, Schoots, O, van Kats, S, Ohara, K, Jovanovic, V, Guan, H C, Bunzow, J R, Petronis, A, Van Tol, H H

“…Recent molecular characterization of the human D4 gene has revealed the existence of various polymorphic forms of this receptor. These variations are found in…”
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Human brain dopamine receptors in children and aging adults by Seeman, P, Bzowej, N H, Guan, H C, Bergeron, C, Becker, L E, Reynolds, G P, Bird, E D, Riederer, P, Jellinger, K, Watanabe, S

“…Since spontaneous oral dyskinesias are more prevalent in the elderly, and since these movements may be controlled by the balance of brain dopamine D1 and D2…”
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LAND COVER CLASSIFICATION FROM FULL-WAVEFORM LIDAR DATA BASED ON SUPPORT VECTOR MACHINES by Zhou, M., Li, C. R., Ma, L., Guan, H. C.

“…In this study, a land cover classification method based on multi-class Support Vector Machines (SVM) is presented to predict the types of land cover in Miyun…”
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LAND COVER CLASSIFICATION FROM FULL-WAVEFORM LIDAR DATA BASED ON SUPPORT VECTOR MACHINES by Zhou, M., Li, C. R., Ma, L., Guan, H. C.

“…In this study, a land cover classification method based on multi-class Support Vector Machines (SVM) is presented to predict the types of land cover in Miyun…”
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Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases by Seeman, P, Bzowej, N H, Guan, H C, Bergeron, C, Reynolds, G P, Bird, E D, Riederer, P, Jellinger, K, Tourtellotte, W W

“…Because dopamine D2 receptors are known to be elevated in schizophrenic brain striata, this study examined whether a similar dopamine receptor elevation…”
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The regulatory effect of GAPLINC in malignant tumors and its relationship with the prognosis of patients by Zhou, Y S, Xu, S W, Guan, C H, Hu, Z T, Jiang, X M

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Serotonin Receptor cDNA Cloned From Lymnaea stagnalis by Sugamori, Kim S., Sunahara, Roger K., Guan, Hong-Chang, Andrew G. M. Bulloch, Tensen, Cees P., Seeman, Philip, Niznik, Hyman B., Hubert H. M. Van Tol

“…Serotonin (5-HT) is a major neurotransmitter that influences various behaviors, neuronal plasticity, learning, and memory in molluscs. Although the physiology…”
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Dopamine D4 receptors elevated in schizophrenia by Seeman, Philip, Guan, Hong-Chang, Van Tol, Hubert H. M

“…Although the biological basis of schizophrenia is not known, possible causes include genetic defects, viruses, amines, brain structure and metabolism,…”
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Promoter-independent regulation of cell-specific dopamine receptor expression by Knapp, Mark, Wong, Albert H.C, Schoots, Oscar, Guan, H.C, Van Tol, Hubert H.M

“…Here we describe the construction of recombinant adenoviruses expressing dopamine D2 and D4 receptors, and their ability to mediate high levels of heterologous…”
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Multiple dopamine D4 receptor variants in the human population by Van Tol, H H, Wu, C M, Guan, H C, Ohara, K, Bunzow, J R, Civelli, O, Kennedy, J, Seeman, P, Niznik, H B, Jovanovic, V

“…The dopamine D4 receptor structurally and pharmacologically resembles the dopamine D2 and D3 receptors. Clozapine, an atypical antipsychotic that is relatively…”
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Cloning of the gene for a human dopamine D4 receptor with high affinity for antipsychotic clozapine by VAN TOL, H. H. M, BUNZOW, J. R, HONG-CHANG GUAN, SUNAHARA, R. K, SEEMAN, P, NIZNIK, H. B, CIVELLI, O

“…Dopamine receptors belong to the family of G protein-coupled receptors. On the basis of the homology between these receptors, three different dopamine…”
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(.+-.)-3-Allyl-7-halo-8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as selective high affinity D1 dopamine receptor antagonists: synthesis and structure-activity relationship by Baindur, Nandkishore, Tran, Mai, Niznik, Hyman B, Guan, H. C, Seeman, Phillip, Neumeyer, John L

“…Substituted 1-phenyl-3-benzazepines form a class of compounds possessing potent and selective affinity for the D1 DA receptor…”
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Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 by Sunahara, R K, Guan, H C, O'Dowd, B F, Seeman, P, Laurier, L G, Ng, G, George, S R, Torchia, J, Van Tol, H H, Niznik, H B

“…Dopamine receptors belong to a superfamily of receptors that exert their biological effects through guanine nucleotide-binding (G) proteins. Two main dopamine…”
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Dopamine D1 and D2 receptors are sensitive to the cationic form of apomorphine by Seeman, P, Guan, H C

“…The protonated form of apomorphine was found to be active at the high affinity state of dopamine D1 and D2 receptors in canine striatum, since pH reduction…”
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(.+-.)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, a new high affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship by Neumeyer, John L, Baindur, Nandkishore, Niznik, Hyman B, Guan, H. C, Seeman, Philip

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Schizophrenia : elevation of dopamine D4-like sites, using [3H]nemonapride and [125I]epidepride by SEEMAN, P, GUAN, H.-C, VAN TOL, H. H. M

“…We here report a three-fold elevation of dopamine D4-like sites in schizophrenia, using [3H]nemonapride to measure dopamine D2 and D3 receptors and D4-like…”
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Research Progress on Multiple Organ Damage and Mechanism of Cantharidin Poisoning by Zhang, Y Y, Yu, Y L, Zhang, J, Guan, C H, Ren, L, Liu, L

“…Cantharidin poisoning has been proven to cause multiple organ damage. Acute circulatory failure, acute renal failure, and multiple organ failure resulting from…”
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(+/-)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3- benzazepin, a new high-affinity D1 dopamine receptor ligand: synthesis and structure-activity relationship by Neumeyer, J L, Baindur, N, Niznik, H B, Guan, H C, Seeman, P

“…The 7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines form a series of compounds having a high affinity at the D1 dopamine receptor. The 6-chloro…”
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