Search Results - "Gualdoni, A"

Hijacking the Supplies: Metabolism as a Novel Facet of Virus-Host Interaction by Mayer, Katharina A, Stöckl, Johannes, Zlabinger, Gerhard J, Gualdoni, Guido A

“…Viral replication is a process that involves an extremely high turnover of cellular molecules. Since viruses depend on the host cell to obtain the…”
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CD38 Antibody Daratumumab for the Treatment of Chronic Active Antibody-mediated Kidney Allograft Rejection by Doberer, Konstantin, Kläger, Johannes, Gualdoni, Guido A., Mayer, Katharina A., Eskandary, Farsad, Farkash, Evan A., Agis, Hermine, Reiter, Thomas, Reindl-Schwaighofer, Roman, Wahrmann, Markus, Cohen, Gerald, Haslacher, Helmuth, Bond, Gregor, Simonitsch-Klupp, Ingrid, Halloran, Philip F., Böhmig, Georg A.

“…BACKGROUND.Late antibody-mediated rejection (AMR) is a major cause of transplant failure. Potential therapeutic targets are plasma cells (PC) and/or natural…”
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Dual role of miR-1 in the development and function of sinoatrial cells by Benzoni, P., Nava, L., Giannetti, F., Guerini, G., Gualdoni, A., Bazzini, C., Milanesi, R., Bucchi, A., Baruscotti, M., Barbuti, A.

“…miR-1, the most abundant miRNA in the heart, modulates expression of several transcription factors and ion channels. Conditions affecting the heart rate, such…”
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The AMP analog AICAR modulates the Treg/Th17 axis through enhancement of fatty acid oxidation by Gualdoni, Guido A., Mayer, Katharina A., Göschl, Lisa, Boucheron, Nicole, Ellmeier, Wilfried, Zlabinger, Gerhard J.

“…ABSTRACT T cells must tightly regulate their metabolic processes to cope with varying bioenergetic demands depending on their state of differentiation. The…”
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Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation by Gualdoni, Guido A., Lingscheid, Tilman, Schmetterer, Klaus G., Hennig, Annika, Steinberger, Peter, Zlabinger, Gerhard J.

“…Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide…”
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Prospective Tracking of Donor-Reactive T-Cell Clones in the Circulation and Rejecting Human Kidney Allografts by Aschauer, Constantin, Jelencsics, Kira, Hu, Karin, Heinzel, Andreas, Gregorich, Mariella Gloria, Vetter, Julia, Schaller, Susanne, Winkler, Stephan M, Weinberger, Johannes, Pimenov, Lisabeth, Gualdoni, Guido A, Eder, Michael, Kainz, Alexander, Troescher, Anna Regina, Regele, Heinz, Reindl-Schwaighofer, Roman, Wekerle, Thomas, Huppa, Johannes Bernhard, Sykes, Megan, Oberbauer, Rainer

“…Antigen recognition of allo-peptides and HLA molecules leads to the activation of donor-reactive T-cells following transplantation, potentially causing…”
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Next generation sequencing based assessment of the alloreactive T cell receptor repertoire in kidney transplant patients during rejection: a prospective cohort study by Aschauer, Constantin, Jelencsics, Kira, Hu, Karin, Heinzel, Andreas, Vetter, Julia, Fraunhofer, Thomas, Schaller, Susanne, Winkler, Stephan, Pimenov, Lisabeth, Gualdoni, Guido A, Eder, Michael, Kainz, Alexander, Regele, Heinz, Reindl-Schwaighofer, Roman, Oberbauer, Rainer

“…Kidney transplantation is the optimal treatment in end stage renal disease but the allograft survival is still hampered by immune reactions against the…”
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Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis by Göschl, Lisa, Preglej, Teresa, Boucheron, Nicole, Saferding, Victoria, Müller, Lena, Platzer, Alexander, Hirahara, Kiyoshi, Shih, Han-Yu, Backlund, Johan, Matthias, Patrick, Niederreiter, Birgit, Hladik, Anastasiya, Kugler, Maximilian, Gualdoni, Guido A., Scheinecker, Clemens, Knapp, Sylvia, Seiser, Christian, Holmdahl, Rikard, Tillmann, Katharina, Plasenzotti, Roberto, Podesser, Bruno, Aletaha, Daniel, Smolen, Josef S., Karonitsch, Thomas, Steiner, Günter, Ellmeier, Wilfried, Bonelli, Michael

“…Rheumatoid Arthritis (RA) represents a chronic T cell-mediated inflammatory autoimmune disease. Studies have shown that epigenetic mechanisms contribute to the…”
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Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis by Kovarik, Johannes J, Kernbauer, Elisabeth, Hölzl, Markus A, Hofer, Johannes, Gualdoni, Guido A, Schmetterer, Klaus G, Miftari, Fitore, Sobanov, Yury, Meshcheryakova, Anastasia, Mechtcheriakova, Diana, Witzeneder, Nadine, Greiner, Georg, Ohradanova-Repic, Anna, Waidhofer-Söllner, Petra, Säemann, Marcus D, Decker, Thomas, Zlabinger, Gerhard J

“…A crucial role of cell metabolism in immune cell differentiation and function has been recently established. Growing evidence indicates that metabolic…”
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Host-directed therapy with 2-deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2 by Laxmikant Wali, Michael Karbiener, Scharon Chou, Vitalii Kovtunyk, Adam Adonyi, Irene Gösler, Ximena Contreras, Delyana Stoeva, Dieter Blaas, Johannes Stöckl, Thomas R. Kreil, Guido A. Gualdoni, Anna-Dorothea Gorki

“…Rhinoviruses (RVs) and coronaviruses (CoVs) upregulate host cell metabolic pathways such as glycolysis to meet their bioenergetic demands for rapid…”
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Interleukin 1 Receptor Antagonist Anakinra, Intravenous Immunoglobulin, and Corticosteroids in the Management of Critically Ill Adult Patients With Hemophagocytic Lymphohistiocytosis by Wohlfarth, Philipp, Agis, Hermine, Gualdoni, Guido A., Weber, Johannes, Staudinger, Thomas, Schellongowski, Peter, Robak, Oliver

“…Background: Hemophagocytic lymphohistiocytosis (HLH) causes multiple organ dysfunction frequently leading to intensive care unit (ICU) referral and/or death…”
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Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication by Gualdoni, Guido A., Mayer, Katharina A., Kapsch, Anna-Maria, Kreuzberg, Katharina, Puck, Alexander, Kienzl, Philip, Oberndorfer, Felicitas, Frühwirth, Karin, Winkler, Stefan, Blaas, Dieter, Zlabinger, Gerhard J., Stöckl, Johannes

“…Rhinoviruses (RVs) are responsible for the majority of upper airway infections; despite their high prevalence and the resulting economic burden, effective…”
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Quantification of Torque Teno Virus Viremia as a Prospective Biomarker for Infectious Disease in Kidney Allograft Recipients by Strassl, Robert, Schiemann, Martin, Doberer, Konstantin, Görzer, Irene, Puchhammer-Stöckl, Elisabeth, Eskandary, Farsad, Kikic, Željko, Gualdoni, Guido A, Vossen, Mathias G, Rasoul-Rockenschaub, Susanne, Herkner, Harald, Böhmig, Georg A, Bond, Gregor

“…Drug-induced immunosuppression following kidney transplantation is crucial to prevent allograft rejection, but increases risk for infectious disease. Tailoring…”
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MxA for differentiating viral and bacterial infections in adults: a prospective, exploratory study by Metz, Matthäus, Gualdoni, Guido A., Winkler, Heide-Maria, Warenits, Alexandra-Maria, Stöckl, Johannes, Burgmann, Heinz, Winkler, Stefan, Oesterreicher, Zoe Anne

“…Purpose Inappropriate antibiotic prescription in patients with viral infections contributes to the surge of antibiotic resistance. Viral infections induce the…”
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The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells by Mayer, Katharina A., Smole, Ursula, Zhu, Ci, Derdak, Sophia, Minervina, Anastasia A., Salnikova, Maria, Witzeneder, Nadine, Christamentl, Anna, Boucheron, Nicole, Waidhofer‐Söllner, Petra, Trauner, Michael, Hoermann, Gregor, Schmetterer, Klaus G., Mamedov, Ilgar Z., Bilban, Martin, Ellmeier, Wilfried, Pickl, Winfried F., Gualdoni, Guido A., Zlabinger, Gerhard J.

“…The importance of cellular metabolic adaptation in inducing robust T cell responses is well established. However, the mechanism by which T cells link…”
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Resveratrol enhances TNF-α production in human monocytes upon bacterial stimulation by Gualdoni, Guido A., Kovarik, Johannes J., Hofer, Johannes, Dose, Franziska, Pignitter, Marc, Doberer, Daniel, Steinberger, Peter, Somoza, Veronika, Wolzt, Michael, Zlabinger, Gerhard J.

“…Resveratrol is a key component of red wine that has been reported to have anti-carcinogenic and anti-aging properties. Additional studies conducted in vitro…”
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Resveratrol intake enhances indoleamine-2,3-dioxygenase activity in humans by Gualdoni, Guido A, Fuchs, Dietmar, Zlabinger, Gerhard J, Gostner, Johanna M

“…Resveratrol is a polyphenol compound found in various nutrients that was shown to have immunomodulatory, anti-cancerogenic, and cardioprotective effects. The…”
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Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient—Addendum to the Genotype-Phenotype Puzzle by Göschl, Lisa, Winkler, Stefan, Dmytrus, Jasmin, Heredia, Raul Jimenez, Lagler, Heimo, Ramharter, Michael, Scheinecker, Clemens, Bonelli, Michael, Schmetterer, Klaus, Pickl, Winfried F., Grabmeier-Pfistershammer, Katharina, Hershfield, Michael S., Boztug, Kaan, Förster-Waldl, Elisabeth, Gualdoni, Guido A.

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Prevalence and Outcome of Secondary Hemophagocytic Lymphohistiocytosis Among SIRS Patients: Results from a Prospective Cohort Study by Gualdoni, Guido A, Hofmann, Georg A, Wohlfarth, Philipp, Winkler, Heide-Maria, Winkler, Stefan, Haslacher, Helmuth, Thalhammer, Renate, Makristathis, Athanasios, Ratzinger, Franz, Burgmann, Heinz

“…Secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening condition clinically presenting as SIRS (Systemic Inflammatory Response Syndrome)…”
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Pandemic influenza A H1N1 vaccine in recipients of solid organ transplants: Immunogenicity and tolerability outcomes after vero cell derived, non-adjuvanted, whole-virion vaccination by Lagler, Heimo, Wenisch, Judith M, Tobudic, Selma, Gualdoni, Guido A, Rödler, Susanne, Rasoul-Rockenschaub, Susanne, Jaksch, Peter, Redlberger-Fritz, Monika, Popow-Kraupp, Theresia, Burgmann, Heinz

“…Abstract During the 2009/10 pandemic of influenza A (H1N1), the American Society of Transplantation and other health organizations recommended that…”
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