Search Results - "Guadaño‐Ferraz, Ana"

Thyroid hormone transporters—functions and clinical implications by Bernal, Juan, Guadaño-Ferraz, Ana, Morte, Beatriz

“…Key Points Many proteins can mediate thyroid hormone transport, but only mutations in genes encoding MCT8, MCT10 and OATP1C1 have pathophysiological effects…”
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Generation and Characterization of dickkopf3 Mutant Mice by Barrantes, Ivan del Barco, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Obregon, Maria-Jesus, Martinez de Mena, Raquel, Gailus-Durner, Valérie, Fuchs, Helmut, Franz, Tobias J, Kalaydjiev, Svetoslav, Klempt, Martina, Hölter, Sabine, Rathkolb, Birgit, Reinhard, Claudia, Morreale de Escobar, Gabriella, Bernal, Juan, Busch, Dirk H, Wurst, Wolfgang, Wolf, Eckhard, Schulz, Holger, Shtrom, Svetlana, Greiner, Erich, Hrabé de Angelis, Martin, Westphal, Heiner, Niehrs, Christof

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Expression of the cold thermoreceptor TRPM8 in rodent brain thermoregulatory circuits by Ordás, Purificación, Hernández‐Ortego, Pablo, Vara, Hugo, Fernández‐Peña, Carlos, Reimúndez, Alfonso, Morenilla‐Palao, Cruz, Guadaño‐Ferraz, Ana, Gomis, Ana, Hoon, Mark, Viana, Félix, Señarís, Rosa

“…The cold‐ and menthol‐activated ion channel transient receptor potential channel subfamily M member 8 (TRPM8) is the principal detector of environmental cold…”
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Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain by Wang, Yu, Wang, Ting, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Rausell, Estrella

“…Monocarboxylate transporter 8 (MCT8) and organic anion transporter polypeptide 1C1 (OATP1C1) are thyroid hormone (TH) transmembrane transporters that play an…”
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Combined deletion of Mct8 and Dio2 impairs SVZ neurogliogenesis and olfactory function in adult mice by Valcárcel-Hernández, Víctor, Vancamp, Pieter, Butruille, Lucile, Remaud, Sylvie, Guadaño-Ferraz, Ana

“…Within the adult mouse subventricular zone (SVZ), neural stem cells (NSCs) produce neuroblasts and oligodendrocyte precursor cells (OPCs). T3, the active…”
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Mutations of the Thyroid Hormone Transporter MCT8 Cause Prenatal Brain Damage and Persistent Hypomyelination by López-Espíndola, Daniela, Morales-Bastos, Carmen, Grijota-Martínez, Carmen, Liao, Xiao-Hui, Lev, Dorit, Sugo, Ella, Verge, Charles F, Refetoff, Samuel, Bernal, Juan, Guadaño-Ferraz, Ana

“…Context: Mutations in the MCT8 (SLC16A2) gene, encoding a specific thyroid hormone transporter, cause an X-linked disease with profound psychomotor…”
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Adult Mice Lacking Mct8 and Dio2 Proteins Present Alterations in Peripheral Thyroid Hormone Levels and Severe Brain and Motor Skill Impairments by Bárez-López, Soledad, Grijota-Martínez, Carmen, Ausó, Eva, Fernández-de Frutos, Mario, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana

“…Mutations in the thyroid hormone (TH) transporter monocarboxylate transporter 8 (MCT8) lead to peripheral hyperthyroidism and profound psychomotor alterations…”
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Increased anxiety and fear memory in adult mice lacking type 2 deiodinase by Bárez-López, Soledad, Montero-Pedrazuela, Ana, Bosch-García, Daniel, Venero, César, Guadaño-Ferraz, Ana

“…•Deiodinase type 2 (D2) deficiency leads to emotional alterations in adult mice.•D2 deficiency decreases T3 content in hippocampus and most probably in…”
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Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia by López-Espíndola, Daniela, García-Aldea, Ángel, Gómez de la Riva, Inés, Rodríguez-García, Ana Margarita, Salvatore, Domenico, Visser, Theo J., Bernal, Juan, Guadaño-Ferraz, Ana

“…Thyroid hormones (TH) are crucial for brain development; their deficiency during neurodevelopment impairs neural cell differentiation and causes irreversible…”
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Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains by Wang, Ting, Wang, Yu, Montero-Pedrazuela, Ana, Prensa, Lucía, Guadaño-Ferraz, Ana, Rausell, Estrella

“…Monocarboxylate transporter 8 (MCT8) and organic anion-transporting polypeptide 1C1 (OATP1C1) are thyroid hormone (TH) transmembrane transporters relevant for…”
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Thyroid Hormone Availability and Action during Brain Development in Rodents by Bárez-López, Soledad, Guadaño-Ferraz, Ana

“…Thyroid hormones (THs) play an essential role in the development of all vertebrates; in particular adequate TH content is crucial for proper neurodevelopment…”
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Thyroid hormone action in adult neurogliogenic niches: the known and unknown by Valcárcel-Hernández, Victor, Mayerl, Steffen, Guadaño-Ferraz, Ana, Remaud, Sylvie

“…Over the last decades, thyroid hormones (THs) signaling has been established as a key signaling cue for the proper maintenance of brain functions in adult…”
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MCT8 Deficiency: The Road to Therapies for a Rare Disease by Grijota-Martínez, Carmen, Bárez-López, Soledad, Gómez-Andrés, David, Guadaño-Ferraz, Ana

“…Allan-Herndon-Dudley syndrome is a rare disease caused by inactivating mutations in the gene, which encodes the monocarboxylate transporter 8 (MCT8), a…”
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REGULATION OF THE TRANSCRIPTIONAL AND CELLULAR LANDSCAPE OF THE ADULT MOUSE SUBVENTRICULAR ZONE BY THYROID HORMONE SIGNALING by Hernández, Víctor Valcárcel, Vancamp, Pieter, Remaud, Sylvie, Ferraz, Ana Guadaño

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Type 3 Iodothyronine Deiodinase Is Selectively Expressed in Areas Related to Sexual Differentiation in the Newborn Rat Brain by Escámez, María José, Guadaño-Ferraz, Ana, Cuadrado, Ana, Bernal, Juan

“…Thyroid hormone (T4 and T3) concentrations in target tissues are greatly influenced by the activity of iodothyronine deiodinases. Type 1 and 2 deiodinases…”
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Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development by Valcárcel-Hernández, Víctor, López-Espíndola, Daniela, Guillén-Yunta, Marina, García-Aldea, Ángel, López de Toledo Soler, Inés, Bárez-López, Soledad, Guadaño-Ferraz, Ana

“…Mutations in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to profound brain alterations, including myelination impairments, in…”
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A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations by Valcárcel-Hernández, Víctor, Guillén-Yunta, Marina, Bueno-Arribas, Miranda, Montero-Pedrazuela, Ana, Grijota-Martínez, Carmen, Markossian, Suzy, García-Aldea, Ángel, Flamant, Frédéric, Bárez-López, Soledad, Guadaño-Ferraz, Ana

“…Inactivating mutations in the specific thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to an X-linked rare disease named MCT8 deficiency…”
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Defective thyroid hormone transport to the brain leads to astroglial alterations by Guillén-Yunta, Marina, García-Aldea, Ángel, Valcárcel-Hernández, Víctor, Sanz-Bógalo, Ainara, Muñoz-Moreno, Emma, Matheus, Maria Gisele, Grijota-Martínez, Carmen, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana, Bárez-López, Soledad

“…Allan-Herndon-Dudley syndrome (AHDS) is a rare X-linked disorder that causes severe neurological damage, for which there is no effective treatment. AHDS is due…”
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Intranasal delivery of Thyroid hormones in MCT8 deficiency by Grijota-Martínez, Carmen, Bárez-López, Soledad, Ausó, Eva, Refetoff, Samuel, Frey, 2nd, William H, Guadaño-Ferraz, Ana

“…Loss of function mutations in the gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to severe neurodevelopmental defects…”
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STRUCTURAL AND FUNCTIONAL ALTERATIONS AT THE BLOOD-BRAIN BARRIER IN A MOUSE MODEL FOR MCT8 DEFICIENCY by Montero-Pedrazuela, Ana, Guillén-Yunta, Marina, Hernández, Víctor Valcárcel, Ferraz, Ana Guadaño

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