Search Results - "Gu-Jiun Lin"

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  1. 1

    Triptolide suppresses oral cancer cell PD-L1 expression in the interferon-γ-modulated microenvironment in vitro, in vivo, and in clinical patients by Kuo, Chin-Shan, Yang, Cheng-Yu, Lin, Chih-Kung, Lin, Gu-Jiun, Sytwu, Huey-Kang, Chen, Yuan-Wu

    Published in Biomedicine & pharmacotherapy (01-01-2021)
    “…[Display omitted] •PD-L1 is overexpressed in oral cancer patients.•TPL inhibits tumor growth in oral cancer models by downregulating PD-L1.•IFN-γ increases…”
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    Journal Article
  2. 2

    Immunopathogenic Mechanisms and Novel Immune-Modulated Therapies in Rheumatoid Arthritis by Chen, Shyi-Jou, Lin, Gu-Jiun, Chen, Jing-Wun, Wang, Kai-Chen, Tien, Chiung-Hsi, Hu, Chih-Fen, Chang, Chia-Ning, Hsu, Wan-Fu, Fan, Hueng-Chuen, Sytwu, Huey-Kang

    “…Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease of unknown etiology. It is characterized by the presence of rheumatoid factor and…”
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    Journal Article
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    Microglial Nox2 Plays a Key Role in the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Hu, Chih-Fen, Wu, San-Pin, Lin, Gu-Jiun, Shieh, Chi-Chang, Hsu, Chih-Sin, Chen, Jing-Wun, Chen, Shih-Heng, Hong, Jau-Shyong, Chen, Shyi-Jou

    Published in Frontiers in immunology (02-04-2021)
    “…While oxidative stress has been linked to multiple sclerosis (MS), the role of superoxide-producing phagocyte NADPH oxidase (Nox2) in central nervous system…”
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    Journal Article
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    Interleukin 26 Induces Macrophage IL-9 Expression in Rheumatoid Arthritis by Wang, Yi-Hsun, Peng, Yi-Jen, Liu, Feng-Cheng, Lin, Gu-Jiun, Huang, Shing-Hwa, Sytwu, Huey-Kang, Cheng, Chia-Pi

    “…Rheumatoid arthritis (RA) is an autoimmune disease with chronic inflammation, bone erosion, and joint deformation. Synovial tissue in RA patients is full of…”
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    Journal Article
  5. 5

    Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases by Lin, Gu-Jiun, Huang, Shing-Hwa, Chen, Shyi-Jou, Wang, Chih-Hung, Chang, Deh-Ming, Sytwu, Huey-Kang

    “…Melatonin is the major secretory product of the pineal gland during the night and has multiple activities including the regulation of circadian and seasonal…”
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    Journal Article Book Review
  6. 6

    RNF128 regulates neutrophil infiltration and myeloperoxidase functions to prevent acute lung injury by Liu, Pei-Yao, Chen, Chih-Yuan, Lin, Yu-Lung, Lin, Chien-Ming, Tsai, Wen-Chiuan, Tsai, Yu-Ling, Lin, Gu-Jiun, Chen, Yu-Guang, Wang, Shih-Yun, Sun, Rui-Nong, Huang, Yu-Chuan, Chang, Hung, Chen, Ying-Chuan

    Published in Cell death & disease (21-06-2023)
    “…Acute lung injury (ALI) is characterised by severe pulmonary inflammation, alveolar-capillary barrier disruption, and pulmonary oedema. Therefore, establishing…”
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    Journal Article
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    Melatonin possesses an anti-influenza potential through its immune modulatory effect by Huang, Shing-Hwa, Liao, Ching-Len, Chen, Shyi-Jou, Shi, Li-Ge, Lin, Li, Chen, Yuan-Wu, Cheng, Chia-Pi, Sytwu, Huey-Kang, Shang, Shih-Ta, Lin, Gu-Jiun

    Published in Journal of functional foods (01-07-2019)
    “…[Display omitted] •Melatonin exhibits a therapeutic potential in influenza A H1N1 virus infection.•Melatonin elicits anti-inflammatory and immune modulatory…”
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    Journal Article
  9. 9

    Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model by Yang, Cheng-Yu, Tsao, Chang-Huei, Hsieh, Cheng-Chih, Lin, Chih-Kung, Lin, Chun-Shu, Li, Yu-Hsuan, Chang, Wei-Chin, Cheng, Jen-Chen, Lin, Gu-Jiun, Sytwu, Huey-Kang, Wang, Yin-Lai, Chen, Yuan-Wu

    Published in PloS one (17-07-2020)
    “…Dysregulation of histone demethylase Jumonji-C domain-containing protein 5 (JMJD5) has been identified as a great effect on tumorigenesis. Silibinin is a…”
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    Journal Article
  10. 10

    Interleukin 26 Skews Macrophage Polarization Towards M1 Phenotype by Activating cJUN and the NF-κB Pathway by Lin, Yi-Hsuan, Wang, Yi-Hsun, Peng, Yi-Jen, Liu, Feng-Cheng, Lin, Gu-Jiun, Huang, Shing-Hwa, Sytwu, Huey-Kang, Cheng, Chia-Pi

    Published in Cells (Basel, Switzerland) (10-04-2020)
    “…Interleukin 26 (IL-26) is a new member of the IL-10 family that is highly expressed in rheumatoid arthritis (RA). However, the functions of IL-26 produced by…”
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    Journal Article
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    The influence of digitalized examination of the histology laboratory course on medical and dental students: A retrospective study by Ming-Hsien Chiang, Hsin-Chieh Lan, Chia-Pi Cheng, Jang-Yi Chen, Fon-Yi Yin, Gu-Jiun Lin

    Published in Journal of Medical Sciences (01-09-2023)
    “…Background: Histology laboratory courses comprise the study of cell structures, tissues, and body organs, which are mainly examined using a microscope. Two…”
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    Journal Article
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    Decoy Receptor 3 Promotes Preosteoclast Cell Death via Reactive Oxygen Species-Induced Fas Ligand Expression and the IL-1α/IL-1 Receptor Antagonist Pathway by Cheng, Chia-Pi, Chen, Shyi-Jou, Huang, Shing-Hwa, Lin, Gu-Jiun, Lin, Yi-Hsuan, Peng, Ching-Tsung, Peng, Yi-Jen, Sytwu, Huey-Kang

    Published in Mediators of inflammation (2020)
    “…Purpose. Interleukin-1α (IL-1α) is a potent cytokine that plays a role in inflammatory arthritis and bone loss. Decoy receptor 3 (DCR3) is an immune modulator…”
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    Journal Article
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    Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy by Wu, Chia-Chao, Lu, Kuo-Cheng, Lin, Gu-Jiun, Hsieh, Hsin-Yi, Chu, Pauling, Lin, Shih-Hua, Sytwu, Huey-Kang

    Published in Journal of pineal research (01-05-2012)
    “…:  Idiopathic membranous nephropathy (MN), an autoimmune‐mediated glomerulonephritis, is one of the most common causes of nephrotic syndrome in adults…”
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    Journal Article
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    Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis by Hsieh, Cheng-Chih, Yang, Cheng-Yu, Peng, Bo, Ho, Sien-Lin, Tsao, Chang-Huei, Lin, Chih-Kung, Lin, Chun-Shu, Lin, Gu-Jiun, Lin, Heng-Yi, Huang, Hung-Chi, Chang, Szu-Chien, Sytwu, Huey-Kang, Chia, Wei-Tso, Chen, Yuan-Wu

    Published in Biomedicines (29-09-2023)
    “…The dysregulated expression of cyclin genes can lead to the uncontrolled proliferation of cancer cells. Histone demethylase Jumonji-C domain-containing protein…”
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    Journal Article
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    A novel compound NSC745885 exerts an anti-tumor effect on tongue cancer SAS cells in vitro and in vivo by Chen, Yuan-Wu, Huang, Hsu-Shan, Shieh, Yi-Shing, Ma, Kuo-Hsing, Huang, Shing-Hwa, Hueng, Dueng-Yuan, Sytwu, Huey-Kang, Lin, Gu-Jiun

    Published in PloS one (15-08-2014)
    “…Oral squamous cell carcinoma (OSCC) is a prevalent cancer, especially in developing countries. Anthracyclines and their anthraquinone derivatives, such as…”
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    Journal Article
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    Melatonin prolongs islet graft survival in diabetic NOD mice by Lin, Gu-Jiun, Huang, Shing-Hwa, Chen, Yuan-Wu, Hueng, Dueng-Yuan, Chien, Ming-Wei, Chia, Wei-Tso, Chang, Deh-Ming, Sytwu, Huey-Kang

    Published in Journal of pineal research (01-10-2009)
    “…:  Islet transplantation has been established as a potential therapy for type 1 diabetes. However, inflammation, allorejection, and on‐going autoimmune damage…”
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    Journal Article