Search Results - "Gu, Zhichun"

Predictors of mortality in patients with coronavirus disease 2019: a systematic review and meta-analysis by Shi, Changcheng, Wang, Limin, Ye, Jian, Gu, Zhichun, Wang, Shuying, Xia, Junbo, Xie, Yaping, Li, Qingyu, Xu, Renjie, Lin, Nengming

“…Abstract Background Coronavirus disease 2019 (COVID-19) is associated with a high mortality rate, especially in patients with severe illness. We conducted a…”
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A bibliometric analysis using VOSviewer of publications on COVID-19 by Yu, Yuetian, Li, Yujie, Zhang, Zhongheng, Gu, Zhichun, Zhong, Han, Zha, Qiongfang, Yang, Luyu, Zhu, Cheng, Chen, Erzhen

“…As a global pandemic, COVID-19 has aroused great concern in the last few months and a growing number of related researches have been published. Therefore, a…”
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Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials by Wei, Anhua, Gu, Zhichun, Li, Juan, Liu, Xiaoyan, Wu, Xiaofan, Han, Yi, Pu, Jun

“…Background Evidence of the clinical safety of endothelin receptor antagonists (ERAs) is limited and derived mainly from individual trials; therefore, we…”
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Meta-analysis and systematic review of intravascular ultrasound versus angiography-guided drug eluting stent implantation in left main coronary disease in 4592 patients by Wang, Yue, Mintz, Gary S, Gu, Zhichun, Qi, Yue, Liu, Mengru, Wu, Xiaofan

“…Although several meta-analyses have demonstrated the utility of intravascular ultrasound (IVUS) in guiding drug-eluting stent (DES) implantation compared to…”
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In vivo Evaluation and Alzheimer's Disease Treatment Outcome of siRNA Loaded Dual Targeting Drug Delivery System by Zhang, Chi, Gu, Zhichun, Shen, Long, Liu, Xianyan, Lin, Houwen

“…To deliver drugs to treat Alzheimer's Disease (AD), nanoparticles should firstly penetrate through blood brain barrier, and then target neurons. Recently, we…”
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Co-Administration of Amiodarone Increases Bleeding by Affecting Rivaroxaban Pharmacokinetics in Patients with Atrial Fibrillation by Ding, Huamin, Wang, Zi, Wang, Jia, Yao, Yao, Zhang, Chi, Lin, Houwen, Zhou, Yong, Gu, Zhichun, Lv, Qianzhou, Li, Xiaoye

“…This study aimed to investigate the impact of the drug-drug interaction between rivaroxaban and amiodarone on the clinical outcomes in patients with…”
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Does Having a Usual Primary Care Provider Reduce Polypharmacy Behaviors of Patients With Chronic Disease? A Retrospective Study in Hubei Province, China by Wang, Jia, Feng, Zhanchun, Dong, Zhongxin, Li, Wanping, Chen, Chaoyi, Gu, Zhichun, Wei, Anhua, Feng, Da

“…Within China's hierarchical medical system, many patients seek medical care in different hospitals independently without integrated management. As a result,…”
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Rivaroxaban for Thromboembolism Prophylaxis in Patients with Nephrotic Syndrome: A Single-Arm, Prospective Study by Wei, Meng, Wu, Xue, Wang, Liteng, Gu, Zhichun, Tu, Yuanmao, Zhang, Lihua, Zhang, Jiong, Xie, Honglang, Zhou, Qing, Chu, Yanan, Cheng, Zhen, Zhou, Guohua, Song, Qinxin

“…Thromboembolism is a recognized complication of nephrotic syndrome (NS). Evidence supporting the use of rivaroxaban to prevent NS-related thrombosis is limited…”
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Genetic variants influenced the risk of bleeding and pharmacodynamics of rivaroxaban in patients with nonvalvular atrial fibrillation: A multicentre prospective cohort study by Xiang, Qian, Wang, Zhe, Mu, Guangyan, Xie, Qiufen, Liu, Zhiyan, Zhou, Shuang, Zhang, Hanxu, Wang, Zining, Jiang, Jie, Hu, Kun, Zhang, Yatong, Zhao, Zinan, Yuan, Dongdong, Guo, Liping, Wu, Tingting, Zhang, Jinhua, Wang, Na, Xiang, Jing, Gu, Zhichun, Sun, Jianjun, Cui, Yimin

“…Introduction Individual variability of rivaroxaban was observed in clinical application. This study aimed to identify genetic variants associated with the…”
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Application of physiologically based pharmacokinetics modeling in the research of small-molecule targeted anti-cancer drugs by Wang, Xiaowen, Chen, Fang, Guo, Nan, Gu, Zhichun, Lin, Houwen, Xiang, Xiaoqiang, Shi, Yufei, Han, Bing

“…Introduction Physiologically based pharmacokinetics (PBPK) models are increasingly used in the drug research and development, especially in anti-cancer drugs…”
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Risk of Clostridioides difficile infection following different antibiotics: insights from multi-source medical data by Liu, Yangxi, Dai, Mengfei, Zhang, Kanghuai, Zhang, Li, Lin, Bin, Chen, Keyu, Wang, Haitao, Gu, Zhichun, Yu, Yuetian, Wang, Yan

“…•This study elucidated the correlation between individual antibiotics and Clostridioides difficile infection (CDI).•Two methodologies were integrated: network…”
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Mutant CYP3A4/5 Correlated with Clinical Outcomes by Affecting Rivaroxaban Pharmacokinetics and Pharmacodynamics in Patients with Atrial Fibrillation by Li, Xiaoye, Gu, Zhichun, Wang, Zi, Xu, Qing, Ma, Chunlai, Lv, Qianzhou

“…This study was designed to investigate the impact of single-nucleotide polymorphism-encoded cytochrome P450 enzymes (CYP3A4/5) on clinical outcomes of…”
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A preformulation study of marine alkaloid aaptamine: Physicochemical properties investigation and liposomal formulation development toward hepatocellular carcinoma treatment by Geng, Tianjiao, Xue, Haitao, Kong, Can, He, Luping, Wang, Shuping, Ding, Ling, Zou, Xiaoyan, Gu, Zhichun, Liao, Hongze, Lin, Houwen

“…Hepatocellular carcinoma (HCC) is a global health concern with high prevalence and mortality. A marine alkaloid, AP‐427, has been reported to show potential…”
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Abemaciclib increases the risk of venous thromboembolism in breast cancer: Integrate meta-analysis, pharmacovigilance database analysis, and in vitro validation by Hua, Manqi, Xiong, Fei, Chong, Shan, Zhang, Zhuo, Liu, Qianxin, Hou, Jingyi, Zhang, Zhiqi, Gu, Zhichun, Cui, Xiangli, Cui, Yimin, Xu, Ling, Xiang, Qian

“…•Increasing reports of CDK4/6i-associated venous thromboembolism (VTE) have garnered attention.•Currently, the mechanism underlying VTE occurrence associated…”
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Prevalence, contemporary trends and associated factors of potentially inappropriate prescription of edoxaban in real‐world clinical practice: A subanalysis of the SUNSHINE registry by Zhao, Shujuan, Dai, Hengfen, Chen, Jiaxin, Ni, Ming, Peng, Wenxing, Li, Xiaoyu, Li, Fen, Chen, Boya, Cai, Haixia, Liu, Yinping, Gu, Zhichun, Du, Song, Ma, Peizhi

“…Aim As the direct oral anticoagulant most recently approved in China, data pertaining to clinical edoxaban use are still scarce. This study investigated the…”
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Burden of heart failure in Asia, 1990–2019: findings from the Global Burden of Disease Study 2019 by Zhang, Chi, Xie, Bo, Wang, Xin, Pan, Mangmang, Wang, Jia, Ding, Huamin, Li, Tiejun, Lin, Houwen, Gu, Zhichun

“…Heart failure (HF) is on the rise as a global health problem, but information on its burden in Asia is limited. This study aimed to assess the burden, trends,…”
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Ticagrelor-induced life-threatening bleeding via the cyclosporine-mediated drug interaction: A case report by Zhang, Chi, Shen, Long, Cui, Min, Liu, Xiaoyan, Gu, Zhichun

“…Ticagrelor has become one of the first-line antiplatelet agents in acute coronary syndrome (ACS) patients recommend by the guideline due to its more potent and…”
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Acute stent thrombosis after stent-assisted coiling in an intracranial aneurysm patient carrying two reduced-function CYP2C19 alleles: A case report by Ding, Lanping, Gu, Zhichun, Wang, Rong, Li, Yichen, Fang, Yun

“…Stent thrombosis (ST) remains a thorny issue in spite of dual antiplatelet treatment with aspirin plus clopidogrel after stent-assisted coiling (SAC). We…”
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QTc prolongation and torsades de pointes due to a coadministration of fluoxetine and amiodarone in a patient with implantable cardioverter–defibrillator: Case report and review of the literature by Wei, Anhua, Peng, Jinlan, Gu, Zhichun, Li, Juan

“…Drug-induced prolongation of the corrected QT interval (QTc) may lead to serious and potentially life-threatening ventricular tachyarrhythmia, such as torsades…”
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Incidence and risk of respiratory tract infection associated with specific drug therapy in pulmonary arterial hypertension: a systematic review by Gu, Zhichun, Zhang, Chi, Wei, Anhua, Cui, Min, Pu, Jun, Lin, Houwen, Liu, Xiaoyan

“…Specific drug therapy has been proven to improve functional capacity and slow disease progression in pulmonary arterial hypertension (PAH), regretfully with…”
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