Search Results - "Gu, Yugui"
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Cobalt-Catalyzed Z to E Isomerization of Alkenes: An Approach to (E)‑β-Substituted Styrenes
Published in Organic letters (07-02-2020)“…An efficient cobalt-catalyzed Z to E isomerization of β-substituted styrenes using the amido-diphosphine ligand was developed, delivering the (E)-isomers with…”
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Design, Synthesis, and Structure–Activity Relationship Study of Novel Indole-2-carboxamide Derivatives as Anti-inflammatory Agents for the Treatment of Sepsis
Published in Journal of medicinal chemistry (26-05-2016)“…Sepsis is characterized by a systemic inflammatory response syndrome. Derivatives of indole have been reported to exhibit diverse biological activities. This…”
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Iodine‐Mediated Coupling of Cyclic Amines with Sulfonyl Hydrazides: an Efficient Synthesis of Vinyl Sulfone Derivatives
Published in European journal of organic chemistry (26-01-2021)“…An efficient iodine‐mediated coupling of cyclic amines with sulfonyl hydrazides is reported. This transformation opens a new route to the synthesis of vinyl…”
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4
Transition‐Metal‐Free Radical C−H Methylation of Quinoxalinones with TBHP
Published in Asian journal of organic chemistry (01-02-2020)“…A highly efficient and generally applicable iodine‐mediated C−H methylation of quinoxalinones by using TBHP as the methylating reagent was developed. The…”
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Potassium tert-butoxide-mediated metal-free synthesis of sulfonamides from sodium sulfinates and N,N-disubstituted formamides
Published in Tetrahedron letters (18-07-2018)“…[Display omitted] •A novel amination of sodium sulfinates has been developed.•N,N-disubstituted formamides were decarbonylated to form amine sources.•The…”
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Design, synthesis and biological evaluation of novel 2-sulfonylindoles as potential anti-inflammatory therapeutic agents for treatment of acute lung injury
Published in European journal of medicinal chemistry (05-12-2018)“…Acute lung injury (ALI) is primarily driven by inflammation that severely impacts lung function. Novel 2-sulfonylindoles were recently shown to exhibit…”
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Piezoelectric and photothermal dual functional film for enhanced dermal wound regeneration via upregulation of Hsp90 and HIF-1α
Published in Applied materials today (01-09-2020)“…•A piezoelectric and photothermal dual functional film is simply fabricated.•The film enhances dermal wound healing by electric stimulation and NIR induced…”
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Design, Synthesis, and Structure–Activity Relationship Analysis of Thiazolo[3,2‐a]pyrimidine Derivatives with Anti‐inflammatory Activity in Acute Lung Injury
Published in ChemMedChem (06-07-2017)“…Acute lung injury (ALI) has a high lethality rate, and interleukin‐6 (IL‐6) and tumor necrosis factor‐α (TNF‐α) contribute most to tissue deterioration in…”
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Structure-based discovery of LpxC inhibitors
Published in Bioorganic & medicinal chemistry letters (15-04-2017)“…[Display omitted] The emergence and spread of multidrug-resistant (MDR) Gram negative bacteria presents a serious threat for public health. Novel…”
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Cover Picture: Design, Synthesis, and Structure–Activity Relationship Analysis of Thiazolo[3,2‐a]pyrimidine Derivatives with Anti‐inflammatory Activity in Acute Lung Injury (ChemMedChem 13/2017)
Published in ChemMedChem (06-07-2017)“…The front cover picture shows a series of newly discovered compounds with high inhibitory activities against lipopolysaccharide (LPS)‐induced cytokine…”
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Construction and Application of Internal Control Compliance Risk Monitoring System for Power Trading Institutions
Published in 2023 8th Asia Conference on Power and Electrical Engineering (ACPEE) (01-04-2023)“…Power trading institutions need to make a comprehensive analysis of the compliance risks they may face in their business operations and personnel management…”
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