Search Results - "Gu, Yucheng"

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides by Lu, Changhui, Gu, Yang, Wu, Jiang, Gu, Yucheng, Shen, Qilong

“…A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of…”
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Tuning the Reactivity of Difluoromethyl Sulfoximines from Electrophilic to Nucleophilic: Stereoselective Nucleophilic Difluoromethylation of Aryl Ketones by Shen, Xiao, Zhang, Wei, Ni, Chuanfa, Gu, Yucheng, Hu, Jinbo

“…A stereoselective synthesis of enantiomerically enriched difluoromethyl tertiary alcohols by tuning the reactivity of difluoromethyl sulfoximines from…”
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Concise Synthesis of 9,11-Secosteroids Pinnigorgiols B and E by Li, Xinghui, Zhang, Zeliang, Fan, Huafang, Miao, Yinlong, Tian, Hailong, Gu, Yucheng, Gui, Jinghan

“…Pinnigorgiols B and E are 9,11-secosteroids with a unique tricyclic γ-diketone framework. Herein, we report the first synthesis of these natural products from…”
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Design, Synthesis, and Biological Activities of Spirooxindoles Containing Acylhydrazone Fragment Derivatives Based on the Biosynthesis of Alkaloids Derived from Tryptophan by Chen, Linwei, Xie, Jialin, Song, Hongjian, Liu, Yuxiu, Gu, Yucheng, Wang, Lizhong, Wang, Qingmin

“…On the basis of the biosynthesis of alkaloids derived from tryptophan and considering the wide use of spirooxindole in drug molecular design, a series of novel…”
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Total Syntheses of Echitamine, Akuammiline, Rhazicine, and Pseudoakuammigine by Zhang, Xiang, Kakde, Badrinath N., Guo, Rui, Yadav, Sonyabapu, Gu, Yucheng, Li, Ang

“…Echitamine (1) and akuammiline (2) are representative members of a fascinating class of monoterpenoid indole alkaloids. We report the syntheses of 2 and its…”
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Naturally occurring physalins from the genus Physalis: A review by Wu, Jiangping, Zhao, Jianping, Zhang, Tao, Gu, Yucheng, Khan, Ikhlas A., Zou, Zhongmei, Xu, Qiongming

“…Physalins, including physalins and neophysalins, are a class of highly oxygenated ergostane-type steroids. They are commonly known by the name of…”
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Ligand‐Controlled Copper‐Catalyzed Highly Regioselective Difluoromethylation of Allylic Chlorides/Bromides and Propargyl Bromides by Gu, Yang, Lu, Changhui, Gu, Yucheng, Shen, Qilong

“…Highly regiodivergent copper‐catalyzed allylic/propargylic difluoromethylation reactions by employing different ligands are described. When…”
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Synthesis and anti-tumor activity of 2-amino-3-cyano-6-(1 H-indol-3-yl)-4-phenylpyridine derivatives in vitro by Zhang, Fan, Zhao, Yanfang, Sun, Li, Ding, Lu, Gu, Yucheng, Gong, Ping

“…A series of novel 2-amino-3-cyano-6-(1 H-indol-3-yl)-4-phenylpyridine derivatives were synthesized and their cytotoxic activity against A549, H460, HT-29 and…”
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Study of the antifungal activity of Bacillus vallismortis ZZ185 in vitro and identification of its antifungal components by Zhao, Zhenzhen, Wang, Qiushuo, Wang, Kaimei, Brian, Kemp, Liu, Changhong, Gu, Yucheng

“…An endophytic Bacillus vallismortis ZZ185 was isolated from healthy stems of the plant Broadleaf Holly ( Ilex latifolia Thunb) collected in Nanjing, China…”
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Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Triflates and Its Applications in the Preparation of Difluoromethylated Derivatives of Drug/Agrochemical Molecules by Lu, Changhui, Lu, Hao, Wu, Jiang, Shen, Hong C, Hu, Taishan, Gu, Yucheng, Shen, Qilong

“…A palladium-catalyzed difluoromethylation of a series of aryl chlorides and triflates under mild conditions was described. A variety of common functional…”
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Accuracy Improvement of Binocular Vision Measurement System for Slope Deformation Monitoring by Hu, Qijun, Feng, Ziyuan, He, Leping, Shou, Zihe, Zeng, Junsen, Tan, Jie, Bai, Yu, Cai, Qijie, Gu, Yucheng

“…This paper studies the limitations of binocular vision technology in monitoring accuracy. The factors affecting the surface displacement monitoring of the…”
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Recent Advances of Bioactive Marine Natural Products in Drug Discovery by Zhang, Qun, Lv, Liuxia, Wang, Wenhui, Wei, Meiyan, Gu, Yucheng, Shao, Changlun

“…Marine natural products (MNPs) are valuable resources for drug development. To date, 17 drugs from marine sources are in clinical use, and 33 pharmaceutical…”
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Whole Transcriptome Sequencing of Peripheral Blood Identifies the Alzheimer's Disease-Related circRNA-miRNA-lncRNA Pathway by Gu, Yucheng, Chen, Nihong, Zhu, Lin, Chen, Xiangliang, Jiang, Teng, Zhang, Yingdong

“…Previous studies on transcriptional profiles suggested dysregulation of multiple RNA species in Alzheimer's disease. However, despite recent investigations…”
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Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance by Lin, Lianyun, Wang, Changshi, Wang, Wenlan, Jiang, Heng, Murayama, Takashi, Kobayashi, Takuya, Hadiatullah, Hadiatullah, Chen, Yu Seby, Wu, Shunfan, Wang, Yiwen, Korza, Henryk, Gu, Yucheng, Zhang, Yan, Du, Jiamu, Van Petegem, Filip, Yuchi, Zhiguang

“…The resistance of pests to common insecticides is a global issue that threatens food production worldwide. Diamide insecticides target insect ryanodine…”
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Identification and Heterologous Expression of the Kendomycin B Biosynthetic Gene Cluster from Verrucosispora sp. SCSIO 07399 by Chen, Jiang, Zhang, Shanwen, Chen, Yingying, Tian, Xinpeng, Gu, Yucheng, Ju, Jianhua

“…sp. SCSIO 07399, a rare marine-derived actinomycete, produces a set of ansamycin-like polyketides kendomycin B-D ( - ) which possess potent antibacterial…”
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OSMAC-Based Discovery and Biosynthetic Gene Clusters Analysis of Secondary Metabolites from Marine-Derived Streptomyces globisporus SCSIO LCY30 by Li, Yanqing, Gong, Naying, Zhou, Le, Yang, Zhijie, Zhang, Hua, Gu, Yucheng, Ma, Junying, Ju, Jianhua

“…The one strain many compounds (OSMAC) strategy is an effective method for activating silent gene clusters by cultivating microorganisms under various…”
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Design and Synthesis of Matrine Derivatives as Novel Anti-Pulmonary Fibrotic Agents via Repression of the TGFβ/Smad Pathway by Li, Lingyu, Ma, Liyan, Wang, Dongchun, Jia, Hongmei, Yu, Meng, Gu, Yucheng, Shang, Hai, Zou, Zhongmei

“…A total of 18 matrine derivatives were designed, synthesized, and evaluated for their inhibitory effect against TGF-β1-induced total collagen accumulation in…”
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Design, Synthesis, and Biological Activities of Arylmethylamine Substituted Chlorotriazine and Methylthiotriazine Compounds by Zhao, Huaping, Liu, Yuxiu, Cui, Zhipeng, Beattie, David, Gu, Yucheng, Wang, Qingmin

“…Heterocyclic rings were introduced into the core structure of s-triazine to design and synthesize a series of novel triazines containing arylmethylamino…”
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Characteristic changes in the default mode network in hypertensive patients with cognitive impairment by Gu, Yucheng, Liu, Renyuan, Qin, Ruomeng, Chen, Xin, Zou, Junhui, Jiang, Yongcheng, Ye, Qing, Zhang, Bing, Bai, Feng, Xu, Yun

“…Hypertension has a close affinity to brain degeneration and cognitive decline during the aging process. The default mode network (DMN) is usually affected in…”
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Research on the Harmless Treatment of Weak Muddy Intercalation in Red-Bedded Soft Rock via Microwave Energy by Qijun Hu, Yucheng Gu, Zhicheng Liu, Junsen Zeng, Wenjin Zhang, Leping He, Muyao Li

“…The WMI (weak muddy intercalation) is a typical weak structural surface in the red-bedded rock mass; ensuring slope stability by increasing the strength of the…”
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