Search Results - "Gu, Yanghong"

CXCR6 is required for antitumor efficacy of intratumoral CD8+ T cell by Wang, Binglin, Wang, Yi, Sun, Xiaofan, Deng, Guoliang, Huang, Wei, Wu, Xingxin, Gu, Yanghong, Tian, Zhigang, Fan, Zhimin, Xu, Qiang, Chen, Hongqi, Sun, Yang

“…BackgroundIncreasing infiltration of CD8+ T cells within tumor tissue predicts a better prognosis and is essential for response to checkpoint blocking therapy…”
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Intercepting IRE1 kinase‐FMRP signaling prevents atherosclerosis progression by Yildirim, Zehra, Baboo, Sabyasachi, Hamid, Syed M, Dogan, Asli E, Tufanli, Ozlem, Robichaud, Sabrina, Emerton, Christina, Diedrich, Jolene K, Vatandaslar, Hasan, Nikolos, Fotis, Gu, Yanghong, Iwawaki, Takao, Tarling, Elizabeth, Ouimet, Mireille, Nelson, David L, Yates, John R, Walter, Peter, Erbay, Ebru

“…Fragile X Mental Retardation protein (FMRP), widely known for its role in hereditary intellectual disability, is an RNA‐binding protein (RBP) that controls…”
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Simultaneous Screening of the FRAXA and FRAXE Loci for Rapid Detection of FMR1 CGG and/or AFF2 CCG Repeat Expansions by Triplet-Primed PCR by Liu, Timing, Wang, Furene S., Cheah, Felicia S.H., Gu, Yanghong, Shaw, Marie, Law, Hai-Yang, Tay, Stacey K.H., Lee, Caroline G., Nelson, David L., Gecz, Jozef, Chong, Samuel S.

“…Moderate to hyper-expansion of trinucleotide repeats at the FRAXA and FRAXE fragile sites, with or without concurrent hypermethylation, has been associated…”
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Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation by Probst, Frank J., Roeder, Elizabeth R., Enciso, Victoria B., Ou, Zhishuo, Cooper, M. Lance, Eng, Patricia, Li, Jiangzhen, Gu, Yanghong, Stratton, Robert F., Chinault, A. Craig, Shaw, Chad A., Sutton, V. Reid, Cheung, Sau Wai, Nelson, David L.

“…Chromosomal microarray analysis (CMA) by array‐based comparative genomic hybridization (CGH) is a new clinical test for the detection of well‐characterized…”
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Metabolic pathways modulate the neuronal toxicity associated with fragile X-associated tremor/ataxia syndrome by Kong, Ha Eun, Lim, Junghwa, Zhang, Feiran, Huang, Luoxiu, Gu, Yanghong, Nelson, David L, Allen, Emily G, Jin, Peng

“…Abstract Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative disorder that affects premutation carriers (55–200 CGG…”
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Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome by Kong, Ha Eun, Lim, Junghwa, Linsalata, Alexander, Kang, Yunhee, Malik, Indranil, Allen, Emily G, Cao, Yiqu, Shubeck, Lisa, Johnston, Rich, Huang, Yanting, Gu, Yanghong, Guo, Xiangxue, Zwick, Michael E, Qin, Zhaohui, Wingo, Thomas S, Juncos, Jorge, Nelson, David L, Epstein, Michael P, Cutler, David J, Todd, Peter K, Sherman, Stephanie L, Warren, Stephen T, Jin, Peng

“…Fragile X–associated tremor/ataxia syndrome (FXTAS) is a debilitating late-onset neurodegenerative disease in premutation carriers of the expanded CGG repeat…”
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MBD5 haploinsufficiency is associated with sleep disturbance and disrupts circadian pathways common to Smith-Magenis and fragile X syndromes by Mullegama, Sureni V, Pugliesi, Loren, Burns, Brooke, Shah, Zalak, Tahir, Raiha, Gu, Yanghong, Nelson, David L, Elsea, Sarah H

“…Individuals with autism spectrum disorders (ASD) who have an identifiable single-gene neurodevelopmental disorder (NDD), such as fragile X syndrome (FXS,…”
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Impaired Conditioned Fear and Enhanced Long-Term Potentiation in Fmr2 Knock-Out Mice by Gu, Yanghong, McIlwain, Kellie L, Weeber, Edwin J, Yamagata, Takanori, Xu, Bisong, Antalffy, Barbara A, Reyes, Christine, Yuva-Paylor, Lisa, Armstrong, Dawna, Zoghbi, Huda, Sweatt, J. David, Paylor, Richard, Nelson, David L

“…FRAXE mental retardation results from expansion and methylation of a CCG trinucleotide repeat located in exon 1 of the X-linked FMR2 gene, which results in…”
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Identification of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG island by Gu, Yanghong, Nelson, David L, Gibbs, Richard A, Shen, Ying

“…Five folate-sensitive fragile sites have been identified at the molecular level to date. Each is characterized by an expanded and methylated trinucleotide…”
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130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus by Timms, K M, Lu, F, Shen, Y, Pierson, C A, Muzny, D M, Gu, Y, Nelson, D L, Gibbs, R A

“…Deficiency of IDs activity results in Hunter Syndrome (mucopolysaccharidosis type II), a fatal X-linked recessive disorder. We report characterization of 28…”
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Impaired Conditioned Fear and Enhanced Long-Term Potentiation inFmr2 Knock-Out Mice by Gu, Yanghong, McIlwain, Kellie L., Weeber, Edwin J., Yamagata, Takanori, Xu, Bisong, Antalffy, Barbara A., Reyes, Christine, Yuva-Paylor, Lisa, Armstrong, Dawna, Zoghbi, Huda, Sweatt, J. David, Paylor, Richard, Nelson, David L.

“…FRAXE mental retardation results from expansion and methylation of a CCG trinucleotide repeat located in exon 1 of the X-linked FMR2 gene, which results in…”
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Cytogenetic analysis of obsessive-compulsive disorder (OCD): Identification of a FRAXE fragile site by Wang, Qing, Gu, Yanghong, Ferguson, James M., Chen, Qiuyun, Boatwright, Scott, Gardiner, James, Below, Cheryl, Espinosa, Janna, Nelson, David L., Shaffer, Lisa G.

“…Obsessive‐compulsive disorder (OCD) is a chronic psychiatric disease characterized by recurrent obsessions, compulsions, or both. The prevalence rate of OCD is…”
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A de novo deletion in FMR1 in a patient with developmental delay by Gu, Y, Lugenbeel, K A, Vockley, J G, Grody, W W, Nelson, D L

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Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation by Probst, Frank J., Roeder, Elizabeth R., Enciso, Victoria B., Ou, Zhishuo, Cooper, M. Lance, Eng, Patricia, Li, Jiangzhen, Gu, Yanghong, Stratton, Robert F., Chinault, A. Craig, Shaw, Chad A., Sutton, V. Reid, Cheung, Sau Wai, Nelson, David L.

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