Search Results - "Gu, Xidong"
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Elemene Injection Overcomes Paclitaxel Resistance in Breast Cancer through AR/RUNX1 Signal: Network Pharmacology and Experimental Validation
Published in Current pharmaceutical design (01-01-2024)“…Paclitaxel (PTX) is a cornerstone chemotherapy for Breast Cancer (BC), yet its impact is limited by emerging resistance. Elemene Injection (EI) has shown…”
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Active metabolites combination therapies: towards the next paradigm for more efficient and more scientific Chinese medicine
Published in Frontiers in pharmacology (18-04-2024)“…Traditional Chinese medicine (TCM) formulae have been studied extensively in various human diseases and have proven to be effective due to their…”
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β-Elemene Reverses Gefitinib Resistance in NSCLC Cells by Inhibiting lncRNA H19-Mediated Autophagy
Published in Pharmaceuticals (Basel, Switzerland) (01-05-2024)“…Lung cancer is a leading cause of mortality worldwide, especially among Asian patients with non-small cell lung cancer (NSCLC) who have epidermal growth factor…”
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Breast microecology improvement using probiotics following needle aspiration in patients with lactational breast abscess: a multi-center randomized double-blind controlled trial
Published in Scientific reports (06-10-2022)“…Although oral probiotics can improve breast microecology and alleviate the inflammatory response, there are no data regarding cases with existing abscesses. We…”
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A miR-20a/MAPK1/c-Myc regulatory feedback loop regulates breast carcinogenesis and chemoresistance
Published in Cell death and differentiation (01-02-2018)“…Chemoresistance often leads to the failure of breast cancer treatment. MicroRNAs (miRNAs) play an important role in the progression and chemoresistance of…”
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6
The predictive value of preoperative serum neutrophil-to-lymphocyte ratio and tumor markers for early breast cancer patients: A retrospective study
Published in Medicine (Baltimore) (12-08-2022)“…Peripheral blood of Neutrophil-to-Lymphocyte ratio (NLR), carcinoma embryonic antigen (CEA), cancer antigen 125 (CA125) and cancer antigen 15–3 (CA15-3) could…”
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Dexamethasone for preventing postoperative nausea and vomiting after mastectomy
Published in Medicine (Baltimore) (24-07-2020)“…Postoperative nausea and vomiting (PONV) is a common complication after mastectomy. Although many researches have been studied the prophylactic effect of…”
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Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF-α-treated triple-negative breast cancer cells
Published in Tumor biology (01-10-2016)“…Overexpression of microRNA-182 (miR-182) is found in multiple cancers, but the association of miR-182 expression with the sensitivity of triple-negative breast…”
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Bioinformatics analysis of prognosis-related long non-coding RNAs in invasive breast carcinoma
Published in Oncology letters (01-07-2020)“…Breast cancer is one of the most common types of cancer among women worldwide and needs more sensitive prognostic biomarkers to improve its treatment. In the…”
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miR-145 suppresses breast cancer cell migration by targeting FSCN-1 and inhibiting epithelial-mesenchymal transition
Published in American journal of translational research (01-01-2016)“…MicroRNAs (miRNAs), small non-coding RNAs, regulate fundamental cellular and developmental processes such as cell growth, apoptosis, migration, and invasion…”
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Abstract PO1-08-05: Using the CTS5 Score to Predict Late Recurrence in Male and Female Estrogen Receptor-Positive Breast Cancer Patients: a SEER database analysis of 65,729 cases
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…Abstract Purpose: The Clinical Treatment Score post-5 years (CTS5) score is a prognostic prediction tool to predict the risk of late distant recurrence in…”
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Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF-[alpha]-treated triple-negative breast cancer cells
Published in Tumor biology (01-10-2016)“…Overexpression of microRNA-182 (miR-182) is found in multiple cancers, but the association of miR-182 expression with the sensitivity of triple-negative breast…”
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13
The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer
Published in Tumor biology (01-09-2015)“…MicroRNAs (miRNAs) are a class of naturally occurring, small, non-coding RNAs which play important roles in diverse biological processes and are acting as key…”
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Neoadjuvant Pyrotinib plus Trastuzumab, Docetaxel, and Carboplatin in Early or Locally Advanced Human Epidermal Receptor 2-Positive Breast Cancer in China: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial
Published in Oncology research and treatment (2023)“…This multicenter, randomized, double-blind, placebo-controlled phase 2 trial compared the efficacy, and safety of adding pyrotinib to trastuzumab, docetaxel,…”
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MicroRNAs-mediated cell fate in triple negative breast cancers
Published in Cancer letters (28-05-2015)“…Highlights • The control of miRNAs plays an important role in cancer initiation and metastasis. • Due to its gene expression, targeted therapies are not…”
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p53 controls colorectal cancer cell invasion by inhibiting the NF-κB-mediated activation of Fascin
Published in Oncotarget (08-09-2015)“…p53 mutation is known to contribute to cancer progression. Fascin is an actin-bundling protein and has been recently identified to promote cancer cell…”
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