Search Results - "Gu, Xiangming"
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Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions
Published in PloS one (16-02-2022)“…Methemoglobin (metHb) arises from the oxidation of ferrous hemoglobin (HbFe2+, Hb) to ferric hemoglobin (HbFe3+, metHb), which is unable to bind gaseous…”
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Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross‐link density
Published in Biotechnology and bioengineering (01-08-2020)“…Previously, our lab developed high molecular weight (MW) tense (T) quaternary state glutaraldehyde polymerized bovine hemoglobins (PolybHbs) that exhibited…”
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3
Early Intervention in Ischemic Tissue with Oxygen Nanocarriers Enables Successful Implementation of Restorative Cell Therapies
Published in Cellular and molecular bioengineering (01-10-2020)“…Background Tissue ischemia contributes to necrosis and infection. While angiogenic cell therapies have emerged as a promising strategy against ischemia,…”
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Boosting Monocular 3D Human Pose Estimation With Part Aware Attention
Published in IEEE transactions on image processing (01-01-2022)“…Monocular 3D human pose estimation is challenging due to depth ambiguity. Convolution-based and Graph-Convolution-based methods have been developed to extract…”
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Tangential flow filtration-facilitated purification of human red blood cell membrane fragments and its preferential use in removing unencapsulated material from resealed red blood cell ghosts compared to centrifugation
Published in Biotechnology progress (30-07-2024)“…The biodistribution of many therapeutics is controlled by the immune system. In addition, some molecules are cytotoxic when not encapsulated inside of larger…”
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Tangential flow filtration facilitated fractionation and PEGylation of low and high‐molecular weight polymerized hemoglobins and their biophysical properties
Published in Biotechnology and bioengineering (01-01-2022)“…Various types of hemoglobin (Hb)‐based oxygen carriers (HBOCs) have been developed as red blood cell substitutes for treating blood loss when blood is not…”
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ZIF-8 metal organic framework nanoparticle loaded with tense quaternary state polymerized bovine hemoglobin: potential red blood cell substitute with antioxidant properties
Published in Nanoscale (18-05-2023)“…Due to several limitations associated with blood transfusion, such as the relatively short shelf life of stored blood, low risk of developing acute immune…”
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Toward Sustainable Metal–Organic Frameworks for Post-Combustion Carbon Capture by Life Cycle Assessment and Molecular Simulation
Published in ACS sustainable chemistry & engineering (13-09-2021)“…Metal–organic frameworks (MOFs), an emerging class of materials, have been regarded as highly promising adsorbent materials for carbon capture and…”
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Disentangled Adversarial Domain Adaptation for Phonation Mode Detection in Singing and Speech
Published in IEEE/ACM transactions on audio, speech, and language processing (2023)“…Phonation mode detection predicts phonation modes and their temporal boundaries in singing and speech, holding promise for characterizing voice quality and…”
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ZIF‑8 Metal–Organic Framework Nanoparticles Loaded with Hemoglobin as a Potential Red Blood Cell Substitute
Published in ACS applied nano materials (22-04-2022)“…Hemoglobin (Hb)-based oxygen carriers (HBOCs) are being developed as artificial red blood cell (RBC) substitutes for use in transfusion medicine…”
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Laser Endoscopic Manipulator Using Spring-Reinforced Multi-DoF Soft Actuator
Published in IEEE robotics and automation letters (01-10-2021)“…The flexible manipulators and related robotic systems have been widely used in minimally invasive surgery (MIS) for enhancing the intraoperative inspection and…”
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Pilot scale production and characterization of next generation high molecular weight and tense quaternary state polymerized human hemoglobin
Published in Biotechnology and bioengineering (01-12-2022)“…Polymerized human hemoglobin (PolyhHb) is being studied as a possible red blood cell (RBC) substitute for use in scenarios where blood is not available. While…”
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Biophysical Analysis and Preclinical Pharmacokinetics–Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute
Published in Biomacromolecules (10-04-2023)“…Red blood cell (RBC) substitutes tested in late-phase clinical trials contained low-molecular-weight hemoglobin species (<500 kDa), resulting in…”
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Comprehensive Characterization of Tense and Relaxed State Glutaraldehyde Polymerized Bovine Hemoglobin as a Function of Cross-link Density
Published in Biotechnology and bioengineering (12-06-2020)“…Previously, our lab developed high molecular weight (MW) tense (T) quaternary state glutaraldehyde polymerized bovine hemoglobins (PolybHbs) that exhibited…”
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15
Distilling a Deep Neural Network into a Takagi-Sugeno-Kang Fuzzy Inference System
Published 10-10-2020“…Deep neural networks (DNNs) demonstrate great success in classification tasks. However, they act as black boxes and we don't know how they make decisions in a…”
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Elucidate Gender Fairness in Singing Voice Transcription
Published 05-08-2023“…It is widely known that males and females typically possess different sound characteristics when singing, such as timbre and pitch, but it has never been…”
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On Calibration of LLM-based Guard Models for Reliable Content Moderation
Published 14-10-2024“…Large language models (LLMs) pose significant risks due to the potential for generating harmful content or users attempting to evade guardrails. Existing…”
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Transfer Learning of wav2vec 2.0 for Automatic Lyric Transcription
Published 20-07-2022“…Automatic speech recognition (ASR) has progressed significantly in recent years due to the emergence of large-scale datasets and the self-supervised learning…”
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Deep Audio-Visual Singing Voice Transcription based on Self-Supervised Learning Models
Published 24-04-2023“…Singing voice transcription converts recorded singing audio to musical notation. Sound contamination (such as accompaniment) and lack of annotated data make…”
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MM-ALT: A Multimodal Automatic Lyric Transcription System
Published 17-02-2023“…Automatic lyric transcription (ALT) is a nascent field of study attracting increasing interest from both the speech and music information retrieval…”
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