Search Results - "Gu, Vivian W"

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation by Gu, Sean X., Tyagi, Tarun, Jain, Kanika, Gu, Vivian W., Lee, Seung Hee, Hwa, Jonathan M., Kwan, Jennifer M., Krause, Diane S., Lee, Alfred I., Halene, Stephanie, Martin, Kathleen A., Chun, Hyung J., Hwa, John

“…The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that…”
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Inhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal Carcinomas by Bogachek, Maria V., Park, Jung M., De Andrade, James P., Lorenzen, Allison W., Kulak, Mikhail V., White, Jeffrey R., Gu, Vivian W., Wu, Vincent T., Weigel, Ronald J.

“…Many solid cancers have an expanded CD44+/hi/CD24−/low cancer stem cell (CSC) population, which are relatively chemoresistant and drive recurrence and…”
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TFAP2C regulates carbonic anhydrase XII in human breast cancer by Franke, Christopher M., Gu, Vivian W., Grimm, Benjamin G., Cassady, Victoria C., White, Jeffrey R., Weigel, Ronald J., Kulak, Mikhail V.

“…The expression of carbonic anhydrase XII ( CA12 ) is associated with the expression of estrogen receptor alpha (ERα) in breast cancer and is linked to a good…”
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AP-2α Regulates S-Phase and Is a Marker for Sensitivity to PI3K Inhibitor Buparlisib in Colon Cancer by Beck, Anna C, Cho, Edward, White, Jeffrey R, Paemka, Lily, Li, Tiandao, Gu, Vivian W, Thompson, Dakota T, Koch, Kelsey E, Franke, Christopher, Gosse, Matthew, Wu, Vincent T, Landers, Shannon R, Pamatmat, Anthony J, Kulak, Mikhail V, Weigel, Ronald J

“…Activating protein 2 alpha (AP-2α; encoded by ) functions as a tumor suppressor and influences response to therapy in several cancer types. We aimed to…”
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A TFAP2C Gene Signature Is Predictive of Outcome in HER2-Positive Breast Cancer by Wu, Vincent T, Kiriazov, Boris, Koch, Kelsey E, Gu, Vivian W, Beck, Anna C, Borcherding, Nicholas, Li, Tiandao, Addo, Peter, Wehrspan, Zachary J, Zhang, Weizhou, Braun, Terry A, Brown, Bartley J, Band, Vimla, Band, Hamid, Kulak, Mikhail V, Weigel, Ronald J

“…The AP-2γ transcription factor, encoded by the gene, regulates the expression of estrogen receptor-alpha (ERα) and other genes associated with hormone response…”
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EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib by De Andrade, James P, Park, Jung M, Gu, Vivian W, Woodfield, George W, Kulak, Mikhail V, Lorenzen, Allison W, Wu, Vincent T, Van Dorin, Sarah E, Spanheimer, Philip M, Weigel, Ronald J

“…Expression of TFAP2C in luminal breast cancer is associated with reduced survival and hormone resistance, partially explained through regulation of RET. TFAP2C…”
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AP-2γ Is Required for Maintenance of Multipotent Mammary Stem Cells by Gu, Vivian W., Cho, Edward, Thompson, Dakota T., Cassady, Victoria C., Borcherding, Nicholas, Koch, Kelsey E., Wu, Vincent T., Lorenzen, Allison W., van der Heide, Dana M., White, Jeffrey R., Kulak, Mikhail V., Williams, Trevor, Zhang, Weizhou, Weigel, Ronald J.

“…Mammary gland ductal morphogenesis depends on the differentiation of mammary stem cells (MaSCs) into basal and luminal lineages. The AP-2γ transcription…”
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Targeting the SUMO pathway as a novel treatment for anaplastic thyroid cancer by De Andrade, James P, Lorenzen, Allison W, Wu, Vincent T, Bogachek, Maria V, Park, Jung M, Gu, Vivian W, Sevenich, Claire M, Cassady, Victoria C, Beck, Anna C, Kulak, Mikhail V, Robinson, Robert A, Lal, Geeta, Weigel, Ronald J

“…Cancer stem cells (CSCs) are expanded in anaplastic thyroid cancer (ATC) and standard treatment approaches have failed to improve survival, suggesting a need…”
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High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease by Gu, Sean X, Marcus, Brian S, Gu, Vivian W, Varghese, Adarsh P, Hwa, John, Faustino, E Vincent S

“…Congenital heart disease (CHD) is a group of complex heart defects associated with hematologic abnormalities, including increased risk of thrombotic and…”
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Multimodality Platelet Evaluation By Mass Cytometry and Genetic Analysis in Patients with Bleeding Disorders by Gu, Sean X, Gallagher, Patrick G, Butt, Ayesha, Gu, Vivian W, Lezon-Geyda, Kimberly, Schulz, Vincent P, Prozora, Stephanie, Lee, Alfred I, Neparidze, Natalia, Bar, Noffar, Martin, Kelsey, Cornell, Jennifer, Chirico, Giavanna, Chakraborty, Raja, Rinder, Henry M, Hwa, John, Bona, Robert D

“…Introduction: Bleeding disorders are a diverse group of conditions characterized by abnormal bleeding tendencies. Platelet dysfunction is a common underlying…”
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