Search Results - "Gu, Qingyang"

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer by Teng, Shuaishuai, Li, Yang Eric, Yang, Ming, Qi, Rui, Huang, Yiming, Wang, Qianyu, Zhang, Yanmei, Chen, Shanwen, Li, Shasha, Lin, Kequan, Cao, Yang, Ji, Qunsheng, Gu, Qingyang, Cheng, Yujing, Chang, Zai, Guo, Wei, Wang, Pengyuan, Garcia-Bassets, Ivan, Lu, Zhi John, Wang, Dong

“…Metastasis, the development of secondary malignant growths at a distance from a primary tumor, is the cause of death for 90% of cancer patients, but little is…”
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Determinants and international influences of the Chinese freight market by Gu, Yimiao, Chen, Zhenxi, Gu, Qingyang

“…The past decades witness the impressive development of China. Along with the huge demand of China for commodities, the Chinese shipping market becomes more and…”
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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition by Shangary, Sanjeev, Qin, Dongguang, McEachern, Donna, Liu, Meilan, Miller, Rebecca S, Qiu, Su, Nikolovska-Coleska, Zaneta, Ding, Ke, Wang, Guoping, Chen, Jianyong, Bernard, Denzil, Zhang, Jian, Lu, Yipin, Gu, Qingyang, Shah, Rajal B, Pienta, Kenneth J, Ling, Xiaolan, Kang, Sanmao, Guo, Ming, Sun, Yi, Yang, Dajun, Wang, Shaomeng

“…We have designed MI-219 as a potent, highly selective and orally active small-molecule inhibitor of the MDM2-p53 interaction. MI-219 binds to human MDM2 with a…”
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iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer by Daifuku, Richard, Zhang, Yu, Wang, Jingjing, Gu, Qingyang

“…Abstract Background iMN013 (5-aza-2',2'-difluorodeoxycytidine), a DNA methyl transferase inhibitor and ribonucleotide reductase inhibitor, and its prodrug…”
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59 Preclinical platform for nucleic acid drug evaluation: siRNA and mRNA therapeutics by Wang, Dong, Qiang, Xiangnan, Zhang, Zhixiang, Gu, Qingyang

“…BackgroundSince the emerging of COVID-19 pandemic, numerous nucleic-acid therapeutics have been approved for clinical use. Distinguishing themselves from…”
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1162 Upregulation of metabolism enzymes mediatesADC resistance in a HER2-positive cancer cell line by Wang, Dong, Qiang, Xiangnan, Zhang, Zhixiang, Gu, Qingyang

“…BackgroundThe receptor tyrosine kinase HER2 is overexpressed in approximately 20% of breast cancer, and its amplification is associated with reduced survival…”
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Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma by Kissel, Maria, Berndt, Sandra, Fiebig, Lukas, Kling, Simon, Ji, Qunsheng, Gu, Qingyang, Lang, Tina, Hafner, Frank-Thorsten, Teufel, Michael, Zopf, Dieter

“…The purpose of this study was to investigate the antitumor activity of regorafenib and sorafenib in preclinical models of HCC and to assess their mechanism of…”
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Effect of polyfluoroalkyl chemicals on the occurrence of urge urinary incontinence: a population-based study by Cui, Shu, Zhao, Xinghua, Chu, Xiaohan, Zhang, Shengwei, Gu, Qingyang, Xu, Changbao

“…Background: The artificial fluorinated group of compounds polyfluoroalkyl chemicals (PFCs) has been applied extensively in daily life for decades, and is…”
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Preparation of quaternized poly(vinylidene fluoride) membranes by γ-ray irradiation induced graft polymerization and their antibacterial property by Gu, Qingyang, Jia, Zhiqian

“…PVDF microfiltration membranes were modified by γ-ray irradiation induced grafting polymerization of 4-vinyl pyridine (4-VP) and then quaternization by n-butyl…”
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Preparation of quaternized poly(vinylidene fluoride) membrane by surface photografting and its antifouling performance for alkaline proteins by Gu, Qingyang, Jia, Zhiqian, Zhen, Tianli

“…PVDF microfiltration membranes were modified by photografting of 4-vinylpyridine and then quaternized with n-butyl chloride. Lysozyme was employed as a model…”
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Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma by Yang, Shuqun, Luo, Chonglin, Gu, Qingyang, Xu, Qiang, Wang, Guan, Sun, Hongye, Qian, Ziliang, Tan, Yexiong, Qin, Yuxin, Shen, Yuhong, Xu, Xiaowei, Chen, Shu-Hui, Chan, Chi-Chung, Wang, Hongyang, Mao, Mao, Fang, Douglas D

“…Hepatocellular carcinoma (HCC) is the fifth most common type of cancers worldwide. However, current therapeutic approaches for this epidemic disease are…”
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466 Combined inhibition of KRAS G12C and PD-1 boosts the therapeutic efficacy via conditioning of tumor microenvironment in pre-clinical humanized NSCLC mouse models by Ni, Ting, Huo, Tongxin, Zhang, Yawen, Wang, Panpan, He, Huacheng, Wang, Jingjing, Shi, Wenting, Qiang, Xiangnan, Gu, Qingyang

“…BackgroundRAS is one of the most frequently mutated oncogenes in lung cancer. The KRAS G12C mutation is present in approximately 39% of KRAS-mutant NSCLC.1…”
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Preparation of phase-transfer catalytic porous membrane by γ-ray irradiation grafting and its application in nucleophilic substitution reaction by Jia, Zhiqian, Zhen, Tianli, Zhang, Xiaoqin, Gu, Qingyang

“…Phase-transfer catalytic porous polyethylene membranes, prepared by γ-ray irradiation grafting of 4-vinyl pyridine and quaternization, were tested in…”
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Baeyer–Villiger co-oxidation of cyclohexanone with Fe–Sn–O catalysts in an O2/benzaldehyde system by Sun, Jingjing, Zhu, Qianqian, Guo, Xiaoyan, Jin, Haibo, He, Guangxiang, Ma, Lei, Zhang, Rongyue, Gu, Qingyang, Yang, Suohe

“…Baeyer–Villiger (BV) oxidation of cyclohexanone to -caprolactone was studied by a co-precipitation method using Fe–Sn–O catalysts in an O /benzaldehyde system…”
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Formation and Application of High Reflectivity Controllable Barium Sulfate Microspheres by Liu, Yuejiao, Guo, Xiaoyan, Gu, Qingyang, He, Guangxiang, Yang, Suohe, Jin, Haibo

“…This paper investigated the influence of reaction conditions on particle morphology. X-ray powder diffraction (XRD), particle size distribution (PSD), and…”
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A new method for fast intercalation of bulk crown ether guest into LDH by Ma, Shulan, Wang, Juan, Du, Li, Sun, Yahong, Gu, Qingyang, Sun, Genban, Yang, Xiaojing

“…[Display omitted] ► Reaction can be accomplished within short time as several minutes at room temperature. ► Products give well-retained morphology, high…”
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Preparation of palladium nanocrystals by membrane absorption of hydrogen by Jia, Zhiqian, Sun, Huijie, Gu, Qingyang, Lang, Huize, Abuduwayit, Hankiz

“…► Palladium nanocrystals were prepared by membrane absorption of hydrogen. ► Pd particle size declines with increased stabilizer-to-PdCl 2 molar ratio. ► Pd…”
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SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection by Tan, Mingjia, Gallegos, Jayme R., Gu, Qingyang, Huang, Yuanhui, Li, Jun, Jin, Yetao, Lu, Hua, Sun, Yi

“…Skp1-cullin-F-box protein (SCF) is a multicomponent E3 ubiquitin (Ub) ligase that ubiquitinates a number of important biologic molecules such as p27,…”
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SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27 by He, Hongbin, Gu, Qingyang, Zheng, Min, Normolle, Daniel, Sun, Yi

“…Sensitive to apoptosis gene (SAG)/regulator of cullins-2/RING box protein 2 is a stress-responsive RING component of Skp-1/Cullins/F-box protein E3 ubiquitin…”
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Navigating China's labyrinth: Singapore government-linked companies and lessons learned from their experiences by Qingyang, Gu, Chan, Sarah

“…The government‐linked companies (GLCs) were among the earliest Singapore firms to venture into China and tap into its rapid economic growth. Riding on their…”
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