Search Results - "Gu, Mengru"

Rheb1 protects against cisplatin-induced tubular cell death and acute kidney injury via maintaining mitochondrial homeostasis by Lu, Qingmiao, Wang, Mingjie, Gui, Yuan, Hou, Qing, Gu, Mengru, Liang, Yan, Xiao, Bo, Zhao, Allan Zijian, Dai, Chunsun

“…Ras homolog enriched in brain (Rheb1), a small GTPase, plays a crucial role in regulating cell growth, differentiation, and survival. However, the role and…”
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Fibroblast mTOR/PPARγ/HGF axis protects against tubular cell death and acute kidney injury by Gui, Yuan, Lu, Qingmiao, Gu, Mengru, Wang, Mingjie, Liang, Yan, Zhu, Xingwen, Xue, Xian, Sun, Xiaoli, He, Weichun, Yang, Junwei, Zhao, Allan Zijian, Xiao, Bo, Dai, Chunsun

“…Kidney fibroblasts play a crucial role in dictating tubular cell fate and the outcome of acute kidney injury (AKI). The underlying mechanisms remain to be…”
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Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation by Gu, Mengru, Jiang, Hanlu, Tan, Mengzhu, Yu, Long, Xu, Ning, Li, Ying, Wu, Han, Hou, Qing, Dai, Chunsun

“…palmitoylation, a reversible post-translational modification, is initiated by the DHHC family of palmitoyltransferases and reversed by several acyl protein…”
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PP2Acα promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNFα production by Liang, Yan, Sun, Xiaoli, Wang, Mingjie, Lu, Qingmiao, Gu, Mengru, Zhou, Lu, Hou, Qing, Tan, Mengzhu, Wang, Sudan, Xue, Xian, Dai, Chunsun

“…Macrophage accumulation and activation play an essential role in kidney fibrosis; however, the underlying mechanisms remain to be explored. By analyzing the…”
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Mechanistic target of rapamycin complex 1 orchestrates the interplay between hepatocytes and Kupffer cells to determine the outcome of immune-mediated hepatitis by Sun, Xiaoli, Ni, Yajie, Lu, Qingmiao, Liang, Yan, Gu, Mengru, Xue, Xian, Dai, Chunsun

“…The cell-cell interaction between hepatocytes and Kupffer cells (KCs) is crucial for maintaining liver homeostasis, and the loss of KCs and hepatocytes is…”
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Complement factor B in high glucose-induced podocyte injury and diabetic kidney disease by Lu, Qingmiao, Hou, Qing, Cao, Kai, Sun, Xiaoli, Liang, Yan, Gu, Mengru, Xue, Xian, Zhao, Allan Zijian, Dai, Chunsun

“…The role and mechanisms for upregulating complement factor B (CFB) expression in podocyte dysfunction in diabetic kidney disease (DKD) are not fully…”
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The Hippo Coactivator TAZ Exacerbates Cisplatin-Induced Acute Renal Injury by Xue, Xian, Zhu, Xingwen, Zhou, Lu, Sun, Xiaoli, Gu, Mengru, Liang, Yan, Tan, Mengzhu, Hou, Qing, Wang, Sudan, Dai, Chunsun

“…Introduction: Transcriptional coactivator with PDZ-binding motif (TAZ), a Hippo signaling pathway effector, maintains the balance of cell proliferation,…”
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The signaling protein Wnt5a promotes TGFβ1-mediated macrophage polarization and kidney fibrosis by inducing the transcriptional regulators Yap/Taz by Feng, Ye, Liang, Yan, Zhu, Xingwen, Wang, Mingjie, Gui, Yuan, Lu, Qingmiao, Gu, Mengru, Xue, Xian, Sun, Xiaoli, He, Weichun, Yang, Junwei, Johnson, Randy L., Dai, Chunsun

“…M2 macrophage polarization is known to underlie kidney fibrosis. We previously reported that most of the members of the Wnt family of signaling proteins are…”
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Protein Phosphatase 2A Cα Reprograms Cellular Energy Metabolism to Promote Tubular Cell Death and Kidney Injury: PO0208 by Gu, Mengru, Dai, Chunsun

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Ovarian Index of KM Mice Influenced by Longer Term Consumption of Microwave-Heated Milk by Han, Xue, Bai, Liqin, Wang, Yabing, Li, Yandong, Zhao, Dandan, Hu, Gaoshuang, Hao, Jianxiong, Gu, Mengru, Guo, Xuqian, Wang, Wen

“…Microwave technology has been widely used in the food industry, but the effect of microwave-heated food on human health is being questioned. Female KM mice…”
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