Search Results - "Gu, Jiangyong"

BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine by Liu, Zhongyang, Guo, Feifei, Wang, Yong, Li, Chun, Zhang, Xinlei, Li, Honglei, Diao, Lihong, Gu, Jiangyong, Wang, Wei, Li, Dong, He, Fuchu

“…Traditional Chinese Medicine (TCM), with a history of thousands of years of clinical practice, is gaining more and more attention and application worldwide…”
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Use of natural products as chemical library for drug discovery and network pharmacology by Gu, Jiangyong, Gui, Yuanshen, Chen, Lirong, Yuan, Gu, Lu, Hui-Zhe, Xu, Xiaojie

“…Natural products have been an important source of lead compounds for drug discovery. How to find and evaluate bioactive natural products is critical to the…”
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Hederagenin potentiated cisplatin- and paclitaxel-mediated cytotoxicity by impairing autophagy in lung cancer cells by Wang, Kun, Liu, Xiaodong, Liu, Quanmeng, Ho, Idy ht, Wei, Xianli, Yin, Ting, Zhan, Yujuan, Zhang, Wenjing, Zhang, Wenbo, Chen, Bonan, Gu, Jiangyong, Tan, Yuhui, Zhang, Lin, Chan, Matthew Tv, Wu, William Kk, Du, Biaoyan, Xiao, Jianyong

“…Autophagy inhibition has been demonstrated to increase the efficacy of conventional chemotherapy. In this study, we identified hederagenin, a triterpenoid…”
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Binding Interaction of Betulinic Acid to α-Glucosidase and Its Alleviation on Postprandial Hyperglycemia by Chen, Shaodan, Lin, Bing, Gu, Jiangyong, Yong, Tianqiao, Gao, Xiong, Xie, Yizhen, Xiao, Chun, Zhan, Janis Yaxian, Wu, Qingping

“…Inhibiting the intestinal α-glucosidase can effectively control postprandial hyperglycemia for type 2 diabetes mellitus (T2DM) treatment. In the present study,…”
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Modular Characteristics and Mechanism of Action of Herbs for Endometriosis Treatment in Chinese Medicine: A Data Mining and Network Pharmacology-Based Identification by Zheng, Weilin, Wu, Jiayi, Gu, Jiangyong, Weng, Heng, Wang, Jie, Wang, Tao, Liang, Xuefang, Cao, Lixing

“…Endometriosis is a common benign disease in women of reproductive age. It has been defined as a disorder characterized by inflammation, compromised immunity,…”
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TIMM9 as a prognostic biomarker in multiple cancers and its associated biological processes by Zhang, Lisheng, Huang, Yan, Yang, Yanting, Liao, Birong, Hou, Congyan, Wang, Yiqi, Qin, Huaiyu, Zeng, Huixiang, He, Yanli, Gu, Jiangyong, Zhang, Ren

“…TIMM9 has been identified as a mediator of essential functions in mitochondria, but its association with pan-cancer is poorly understood. We herein employed…”
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Bioinformatics study of the potential therapeutic effects of ginsenoside Rf in reversing nonalcoholic fatty liver disease by Chen, Lichun, Wang, Liziniu, Ao, Weizhen, Chen, Yu, Li, Songjian, Huang, Zhiguan, Yu, Dan, Dong, Yanwen, Gu, Jiangyong, Zeng, Huiyan

“…Ginsenoside Rf, a tetracyclic triterpenoid only present in Panax ginseng, has been proven to relieve lipid metabolism and inflammatory reactions, which can be…”
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Gu-Ben-Hua-Shi (AESS) formula ameliorates atopic dermatitis via regulating NLRP3 signaling pathways by Li, Xiong, Feng, Luyao, Zhong, Tingjing, Mo, Xiumei, Wang, Dong, Gu, Jiangyong, Chen, Dacan, Zeng, Xing, Yan, Fenggen

“…Gu-ben-hua-shi (AESS) formula is a clinical experienced prescription from Guangdong Hospital of Traditional Chinese Medicine (TCM), which is used to treat…”
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Molecular Docking and Molecular Dynamics Studies on Selective Synthesis of α-Amyrin and β-Amyrin by Oxidosqualene Cyclases from Ilex Asprella by Wu, Zhixue, Xu, Hui, Wang, Meiling, Zhan, Ruoting, Chen, Weiwen, Zhang, Ren, Kuang, Zaoyuan, Zhang, Fengxue, Wang, Kui, Gu, Jiangyong

“…Amyrins are the immediate precursors of many pharmaceutically important pentacyclic triterpenoids. Although various amyrin synthases have been identified,…”
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AICD: an integrated anti-inflammatory compounds database for drug discovery by Wang, Kun, Xiao, Jianyong, Liu, Xiaodong, Jiang, Zhuqiao, Zhan, Yujuan, Yin, Ting, He, Lina, Zhang, Fangyuan, Xing, Shangping, Chen, Bonan, Li, Yingshi, Zhang, Fengxue, Kuang, Zaoyuan, Du, Biaoyan, Gu, Jiangyong

“…Systemic or local inflammation drives the pathogenesis of various human diseases. Small compounds with anti-inflammatory properties hold great potential for…”
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Network pharmacology study on the mechanism of traditional Chinese medicine for upper respiratory tract infection by Zhang, Xinzhuang, Gu, Jiangyong, Cao, Liang, Li, Na, Ma, Yiming, Su, Zhenzhen, Ding, Gang, Chen, Lirong, Xu, Xiaojie, Xiao, Wei

“…Traditional Chinese medicine (TCM) is a multi-component and multi-target agent and could treat complex diseases in a holistic way, especially infection…”
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Corrigendum: Combination effect of three main constituents from Sarcandra glabra inhibits oxidative stress in the mice following acute lung injury: a role of MAPK-NF-κB pathway by Liu, Chunping, Liu, Jian-Xing, Gu, Jiangyong, Liu, Fang, Li, Jin Hua, Yang, Bin, Zheng, Yuan, Li, Jie, Wu, Shou-Hai, Wu, Qing-He, Zhang, Xian, Li, Long-Mei, Yang, Hai-Long, Wang, Lei, Li, Xiong

“…[This corrects the article DOI: 10.3389/fphar.2020.580064.]…”
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Combination Effect of Three Main Constituents From Sarcandra glabra Inhibits Oxidative Stress in the Mice Following Acute Lung Injury: A Role of MAPK-NF-κB Pathway by Liu, Chun-Ping, Liu, Jian-Xing, Gu, Jiangyong, Liu, Fang, Li, Jin-Hua, Bin-Yang, Yuan-Zheng, Jie-Li, Wu, Shou-Hai, Wu, Qing-He, Xian-Zhang, Li, Long-Mei, Yang, Hai-Long, Wang, Lei, Li, Xiong

“…Caffeoylquinic acids, coumarins and dicaffeoyl derivatives are considered to be three kinds of the most abundant bioactive components in , an anti-inflammatory…”
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Identification of Fangjihuangqi Decoction as a late-stage autophagy inhibitor with an adjuvant anti-tumor effect against non-small cell lung cancer by Chen, Qiugu, Liao, Yuan, Liu, Yujiao, Song, Yue, Jiang, Junbo, Zhang, Zhen, Li, Anqi, Zheng, Mengyi, Chen, Xiaoyi, Zhao, Tingxiu, Gu, Jiangyong, Tan, Yuhui, Liu, Xiaoyi, Jiang, Yanjun, Wang, Kun, Yi, Hua, Xiao, Jianyong, Hu, Shan

“…Clinically, although chemotherapy is one of the most commonly used methods of treating tumors, chemotherapeutic drugs can induce autophagic flux and increase…”
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Geospallins A⁻C: New Thiodiketopiperazines with Inhibitory Activity against Angiotensin-Converting Enzyme from a Deep-Sea-Derived Fungus Geosmithia pallida FS140 by Sun, Zhang-Hua, Gu, Jiangyong, Ye, Wei, Wen, Liang-Xi, Lin, Qi-Bin, Li, Sai-Ni, Chen, Yu-Chan, Li, Hao-Hua, Zhang, Wei-Min

“…Three new thiodiketopiperazines, geospallins A⁻C ( ⁻ ), together with nine known analogues ( ⁻ ), were isolated from the culture of the deep-sea…”
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Grifolamine A, a novel bis-γ-butyrolactone from Grifola frondosa exerted inhibitory effect on α-glucosidase and their binding interaction: Affinity and molecular dynamics simulation by Chen, Shaodan, Mu, Zhenqiang, Yong, Tianqiao, Gu, Jiangyong, Zhang, Yifan, Gao, Xiong, Xie, Yizhen, Xiao, Chun, Hu, Huiping, Yang, Xiaobing, Li, Xiangmin, Cai, Manjun, Wu, Qingping

“…A novel bis-γ-butyrolactone grifolamine A (1), the first γ-butyrolactone dimer from nature, together with three known γ-butyrolactones (2–4), was isolated from…”
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System-level Study on Synergism and Antagonism of Active Ingredients in Traditional Chinese Medicine by Using Molecular Imprinting Technology by Chen, Tengfei, Gu, Jiangyong, Zhang, Xinzhuang, Ma, Yimin, Cao, Liang, Wang, Zhenzhong, Chen, Lirong, Xu, Xiaojie, Xiao, Wei

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Computational pharmacological studies on cardiovascular disease by Qishen Yiqi Diwan by Gu, JiangYong, Yuan, Gu, Zhu, YongHong, Xu, XiaoJie

“…Computational pharmacological methods were used to study the distribution of 1729 compounds contained in a Chinese medicine,Qishen Yiqi Diwan,in chemical…”
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Molecular mechanism of PSORI-CM01 for psoriasis by regulating the inflammatory cytokines network by Xie, Mingxiang, Zhang, Miaomiao, Qiao, Yuanyuan, Yang, Yibing, Xie, Fuda, Chen, Lichun, Liu, Na, Gu, Jiangyong

“…Psoriasis is an inflammatory skin disease, there is no radical cure. Traditional Chinese medicine has accumulated a lot of clinical experience in the treatment…”
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Rosmarinic acid protects mice from imiquimod induced psoriasis‐like skin lesions by inhibiting the IL‐23/Th17 axis via regulating Jak2/Stat3 signaling pathway by Zhang, Miaomiao, Li, Ning, Cai, Ruhang, Gu, Jiangyong, Xie, Fuda, Wei, Hong, Lu, Chuanjian, Wu, Dinghong

“…IL‐23/Th17 (IL‐17) axis plays a critical role in psoriasis. Rosmarinic acid (RA) was proved the inhibitory effect of T cell infiltration in the skin. However,…”
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