Search Results - "Gu, Frank"

Iron oxide nanoparticles for targeted cancer imaging and diagnostics by Rosen, Joshua E, Chan, Lorena, Shieh, Dar-Bin, DDS, DMSc, Gu, Frank X., PhD

“…Abstract Superparamagnetic iron oxide nanoparticles (SPIONs) have proven to be highly effective contrast agents for the magnetic resonance imaging diagnosis of…”
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Materials for Sustained and Controlled Release of Nutrients and Molecules To Support Plant Growth by Davidson, Drew, Gu, Frank X

“…Controlled release fertilizers (CRFs) are a branch of materials that are designed to improve the soil release kinetics of chemical fertilizers to address…”
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Colorimetric biosensing of pathogens using gold nanoparticles by Verma, Mohit S., Rogowski, Jacob L., Jones, Lyndon, Gu, Frank X.

“…Rapid detection of pathogens is crucial to minimize adverse health impacts of nosocomial, foodborne, and waterborne diseases. Gold nanoparticles are extremely…”
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Decontamination of N95 masks for re-use employing 7 widely available sterilization methods by Kumar, Anand, Kasloff, Samantha B, Leung, Anders, Cutts, Todd, Strong, James E, Hills, Kevin, Gu, Frank X, Chen, Paul, Vazquez-Grande, Gloria, Rush, Barret, Lother, Sylvain, Malo, Kimberly, Zarychanski, Ryan, Krishnan, Jay

“…The response to the COVID-19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95…”
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Understanding why superspreading drives the COVID-19 pandemic but not the H1N1 pandemic by Chen, Paul Z, Koopmans, Marion, Fisman, David N, Gu, Frank X

“…Generally, k remains similar across distinct outbreaks of a virus.1 Studies have documented this for SARS-CoV-2, including across disparate geographical…”
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Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles by Dhar, Shanta, Gu, Frank X, Langer, Robert, Farokhzad, Omid C, Lippard, Stephen J

“…Cisplatin is used to treat a variety of tumors, but dose limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer…”
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From prevention to diagnosis and treatment: Biomedical applications of metal nanoparticle-hydrogel composites by Clasky, Aaron J., Watchorn, Jeffrey D., Chen, Paul Z., Gu, Frank X.

“…Recent advances in biomaterials integrate metal nanoparticles with hydrogels to generate composite materials that exhibit new or improved properties. By…”
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Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols by Chen, Paul Z, Bobrovitz, Niklas, Premji, Zahra, Koopmans, Marion, Fisman, David N, Gu, Frank X

“…Which virological factors mediate overdispersion in the transmissibility of emerging viruses remains a long-standing question in infectious disease…”
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Investigating the Molecular Mechanism of Protein-Polymer Binding with Direct Saturation Compensated Nuclear Magnetic Resonance by Watchorn, Jeffrey, Burns, Darcy, Stuart, Samantha, Gu, Frank X

“…Herein, we describe a new technique, direct saturation compensated transfer (DISCO) NMR, to characterize protein-macromolecule interactions. DISCO enables the…”
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Ion-Mediated Cross-Linking of Hyaluronic Acid into Hydrogels without Chemical Modification by Prakash, Gayatri, Clasky, Aaron J., Gadani, Kunal, Nazeri, Mohammad, Gu, Frank X.

“…Hyaluronic acid (HA) is a biomedically relevant polymer widely explored as a component of hydrogels. The prevailing approaches for cross-linking HA into…”
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Unsaturated Transport and Targeted Binding of Pluronic-Coated Nanoparticles: Lysimeter Experiments by Jaberi, Najmeh, Linley, Stuart, Thomson, Neil R., McVey, Kevin, Sra, Kanwartej, Gu, Frank X.

“…AbstractEfficient delivery of engineered nanoparticles (NPs) to a non-aqueous-phase liquid (NAPL) target zone located above the water table requires an…”
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Surface Functionalization of Silica Nanoparticles with Cysteine: A Low-Fouling Zwitterionic Surface by Rosen, Joshua E, Gu, Frank X

“…Herein, we report on the functionalization of silica nanoparticles with a small molecule, the amino acid cysteine, in order to create a low-fouling…”
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Photocatalytic Activity of Hydrogenated TiO2 by Leshuk, Tim, Parviz, Roozbeh, Everett, Perry, Krishnakumar, Harish, Varin, Robert A, Gu, Frank

“…Photocatalysis is a promising advanced water treatment technology, and recently the possibility of using hydrogenation to improve the photocatalytic efficiency…”
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Asymmetric Interfacet Adatom Migration as a Mode of Anisotropic Nanocrystal Growth by Chen, Paul Z., Skirzynska, Arianna, Yuan, Tiange, Voznyy, Oleksandr, Gu, Frank X.

“…Crystals are known to grow nonclassically or via four classical modes (the layer-by-layer, dislocation-driven, dendritic, and normal modes, which generally…”
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Synthesis of Magnetic Rattle-Type Nanostructures for Use in Water Treatment by Linley, Stuart, Leshuk, Timothy, Gu, Frank X

“…A hydrothermal technique to simultaneously remove a SiO2 template and crystallize a TiO2 outer layer was used to create magnetically separable, hollow…”
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Controllable Microfluidic Production of Drug-Loaded PLGA Nanoparticles Using Partially Water-Miscible Mixed Solvent Microdroplets as a Precursor by Xu, Jiang, Zhang, Shusheng, Machado, Anais, Lecommandoux, Sébastien, Sandre, Olivier, Gu, Frank, Colin, Annie

“…We present a versatile continuous microfluidic flow-focusing method for the production of Doxorubicin (DOX) or Tamoxifen (TAM)-loaded…”
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Microfluidic Platform for Controlled Synthesis of Polymeric Nanoparticles by Karnik, Rohit, Gu, Frank, Basto, Pamela, Cannizzaro, Christopher, Dean, Lindsey, Kyei-Manu, William, Langer, Robert, Farokhzad, Omid C

“…A central challenge in the development of drug-encapsulated polymeric nanoparticles is the inability to control the mixing processes required for their…”
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Nanomaterials for Ocular Drug Delivery by Liu, Shengyan, Jones, Lyndon, Gu, Frank X.

“…Efficient drug delivery to the eye remains a challenging task for pharmaceutical scientists. Due to the various anatomical barriers and the clearance…”
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Pharmacological, Structural, and Drug Delivery Properties and Applications of 1,3-β-Glucans by Lehtovaara, Benjamin C, Gu, Frank X

“…1,3-β-Glucans are a class of natural polysaccharides with unique pharmacological properties and the ability to form single- and triple-helical structures that…”
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SARS-CoV-2 shedding dynamics across the respiratory tract, sex, and disease severity for adult and pediatric COVID-19 by Chen, Paul Z, Bobrovitz, Niklas, Premji, Zahra A, Koopmans, Marion, Fisman, David N, Gu, Frank X

“…Previously, we conducted a systematic review and analyzed the respiratory kinetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Chen et…”
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