Search Results - "Gu, AnXin"

Ultra-high dose rate effect on circulating immune cells: A potential mechanism for FLASH effect? by Jin, Jian-Yue, Gu, Anxin, Wang, Weili, Oleinick, Nancy L., Machtay, Mitchell, (Spring) Kong, Feng-Ming

“…•Computer simulation showed a strong sparing effect on circulating immune cells.•Threshold FLASH dose rate consistent with reported FLASH dose rate in animal…”
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Electroacupuncture alleviates polycystic ovary syndrome-like symptoms through improving insulin resistance, mitochondrial dysfunction, and endoplasmic reticulum stress via enhancing autophagy in rats by Peng, Yan, Guo, Liyuan, Gu, Anxin, Shi, Beibei, Ren, Yukun, Cong, Jing, Yang, Xinming

“…Electroacupuncture (EA), a treatment derived from traditional Chinese medicine, can effectively improve hyperandrogenism and insulin resistance in patients…”
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PTK7-Targeting CAR T-Cells for the Treatment of Lung Cancer and Other Malignancies by Jie, Yamin, Liu, Guijun, Feng, Lina, Li, Ying, E, Mingyan, Wu, Liangliang, Li, Yinyin, Rong, Guanghua, Li, Yongwu, Wei, Huafeng, Gu, Anxin

“…In spite of impressive success in treating hematologic malignancies, adoptive therapy with chimeric antigen receptor modified T cells (CAR T) has not yet been…”
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RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway by Gu, Anxin, Jie, Yamin, Sun, Liang, Zhao, Shuping, E, Mingyan, You, Qingshan

“…Radiation-induced heart disease (RIHD), which is a serious side effect of the radiotherapy applied for various tumors due to the inevitable irradiation of the…”
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Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer by Zhuang, Ming, Jiang, Shan, Gu, Anxin, Chen, Xuesong, E, Mingyan

“…•siRNA-SP1-loaded AuNPs (AuNPs-si-SP1) inhibits SP1 expression in lung cancer cells.•GZMB expression is elevated by silencing SP1 in lung cancer…”
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Molecular characterization based on tumor microenvironment-related signatures for guiding immunotherapy and therapeutic resistance in lung adenocarcinoma by Jie, Yamin, Wu, Jianing, An, Dongxue, Li, Man, He, Hongjiang, Wang, Duo, Gu, Anxin, E, Mingyan

“…Although the role of tumor microenvironment in lung adenocarcinoma (LUAD) has been explored in a number of studies, the value of TME-related signatures in…”
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Novel structured ADAM17 small-molecule inhibitor represses ADAM17/Notch pathway activation and the NSCLC cells' resistance to anti-tumour drugs by Chi, Meng, Jie, Yamin, Li, Ying, Wang, Duo, Li, Man, Li, Dan, E, Mingyan, Li, Yongwu, Liu, Na, Gu, Anxin, Rong, Guanghua

“…The outcomes of current treatment for non-small cell lung cancer (NSCLC) are unsatisfactory and development of new and more efficacious therapeutic strategies…”
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The clinical and genomic distinctions of Class1/2/3 BRAF-mutant colorectal cancer and differential prognoses by Chen, Yungchang, Sun, Hao, Deng, Yanhong, Ma, Yutong, Huang, He, Liu, Yang, Zhang, Yaru, Zhang, Hongyu, Ye, Sheng, E, Mingyan, Guo, Hongqiang, Wu, Mengmeng, Wu, Chunman, Pu, Xingxiang, Chen, Xinggui, Liang, Chaoyong, Ou, Qiuxiang, Weng, Huawei, Wu, Xue, Shao, Yang, Gu, Anxin, Lin, Tongyu

“…BRAF mutations are the oncogenic drivers in colorectal cancer and V600 mutations (Class1), which lead to RAS-independent active monomers, are the most common…”
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Mechanism and Research Progress of Microbiome in the Development of Lung Cancer by Liu, Guohui, Gu, Anxin, E, Mingyan

“…Lung cancer is one of the most common malignant tumors with poor prognosis in China, and most patients are diagnosed as advanced patients. Studies have shown…”
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Does radiation increase the risk of immunotherapy related pneumonitis in cancer patients with thorax radiotherapy combined immune checkpoint inhibitors: A meta-analysis by Jie, Yamin, Gu, Anxin, Fu, Pingfu, Kong, Feng-Ming Spring

“…Abstract only e15099 Background: Thorax radiotherapy (TRT) combined with immunotherapy has shown promising results. However, it remains unclear whether TRT…”
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Novel small molecule inhibitors of the transcription factor ETS-1 and their antitumor activity against hepatocellular carcinoma by Jie, Yamin, Liu, Guijun, E, Mingyan, Li, Ying, Xu, Guo, Guo, Jingjing, Li, Yinyin, Rong, Guanghua, Li, Yongwu, Gu, Anxin

“…The transcription factor ETS-1 (E26 transformation specific sequence 1) is the key regulator for malignant tumor cell proliferation and invasion by mediating…”
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Tricetin attenuates atherosclerosis by suppressing macrophage ferroptosis via activation of the NRF2 pathway by Lin, Quan, Ding, Shaohua, Shi, Manru, Cao, Yang, Liu, Jiayin, Sun, Di, Xu, Weiwei, Pang, Sainan, Gu, Anxin, Mingyan, E

“…•Tricetin (TRI) suppresses macrophage ferroptosis via NRF2 activation in AS.•TRI reduces oxidative stress and lipid peroxidation in ox-LDL-treated…”
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Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer: AuNPs-si-SP1 regulates GZMB for radiosensitivity by Zhuang, Ming, Jiang, Shan, Gu, Anxin, Chen, Xuesong, E, Mingyan

“…• siRNA-SP1-loaded AuNPs (AuNPs-si-SP1) inhibits SP1 expression in lung cancer cells. • GZMB expression is elevated by silencing SP1 in lung cancer cells. •…”
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MicroRNA-144 functions as a tumor suppressor in gastric cancer by targeting cyclooxygenase-2 by Yao, Qiang, Gu, Anxin, Wang, Zhuozhong, Xue, Yingwei

“…Gastric cancer (GC) poses a serious public health threat and the 5-year survival rate of patients with GC is low. MicroRNAs (miRNAs/miRs) may serve oncogenic…”
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Slug Is Associated With Tumor Metastasis and Angiogenesis in Ovarian Cancer by Gu, Anxin, Jie, Yamin, Yao, Qiang, Zhang, Yuqi, Mingyan, E

“…Ovarian cancer is the most lethal gynecologic malignancy among women and usually initiated by the malignant transformation of epithelial cells. The progression…”
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Effect of autophagy on the resveratrol‐induced apoptosis of ovarian cancer SKOV3 cells by Wang, HongYan, Peng, Yan, Wang, Jing, Gu, AnXin, Li, Qi, Mao, DongWei, Guo, LiYuan

“…Objective This study aims to evaluate the relationship between apoptosis and autophagy induced by resveratrol (Res) in SKOV3 human ovarian cancer cell lines…”
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RhNRG-1[beta] Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway by Gu, Anxin, Jie, Yamin, Sun, Liang, Zhao, Shuping, E, Mingyan, You, Qingshan

“…Radiation-induced heart disease (RIHD), which is a serious side effect of the radiotherapy applied for various tumors due to the inevitable irradiation of the…”
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Anticancer activity and molecular mechanism of resveratrol-bovine serum albumin nanoparticles on subcutaneously implanted human primary ovarian carcinoma cells in nude mice by Guo, Liyuan, Peng, Yan, Yao, Jingping, Sui, Lihua, Gu, Anxin, Wang, Jing

“…This study investigates the antitumor effects and functional mechanism of resveratrol-bovine serum albumin nanoparticles (RES-BSANP) on human primary ovarian…”
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Metabolic volume parameters based on different thresholds with baseline 18F-FDG PET/CT as prognostic factors for survival in stage III non-small cell lung cancer by Jie, Yamin, Meng, Xue, Gu, Anxin, Sun, Xiaorong, Yu, Jinming

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