Search Results - "Grzesiuk, Elżbieta"

Contamination of aquatic environment with anticancer reagents influences Daphnia magna – Ecotoxicogenomics approach by Mielecki, Damian, Grzesiuk, Elżbieta, Bednarska, Anna, Garbicz, Damian, Świderska, Bianka, Grzesiuk, Malgorzata

“…Pharmaceuticals used in human medicine contaminate freshwater ecosystems. Chemotherapeutics applied in cancer treatment are found in freshwaters at low…”
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ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy by Pilžys, Tomaš, Marcinkowski, Michał, Kukwa, Wojciech, Garbicz, Damian, Dylewska, Małgorzata, Ferenc, Karolina, Mieczkowski, Adam, Kukwa, Andrzej, Migacz, Ewa, Wołosz, Dominika, Mielecki, Damian, Klungland, Arne, Piwowarski, Jan, Poznański, Jarosław, Grzesiuk, Elżbieta

“…The nine identified human homologues of E . coli AlkB 2-oxoglutarate (2OG) and Fe(II)-dependent dioxygenase, ALKBH1-8 and FTO, display different substrate…”
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How cyclophosphamide at environmentally relevant concentration influences Daphnia magna life history and its proteome by Grzesiuk, Małgorzata, Mielecki, Damian, Pilżys, Tomasz, Garbicz, Damian, Marcinkowski, Michał, Grzesiuk, Elżbieta

“…The waste of commonly used medicines is known to contaminate freshwater ecosystems. Pharmaceuticals can be toxic, mutagenic, or modifying to freshwater…”
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Selected ALKBH dioxygenases are overexpressed in salivary gland tumours by Marcinkowski, Michał, Garbicz, Damian, Pilžys, Tomaš, Kukwa, Wojciech, Grzesiuk, Elżbieta

“…Salivary gland tumours (SGTs) are a heterogeneous group of benign tumours of various origins and pathologies, showing a number of DNA modifications…”
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The proteomic profile is altered but not repaired after bariatric surgery in type 2 diabetes pigs by Ferenc, Karolina, Marcinkowski, Michał, Olszewski, Jarosław, Kowalczyk, Paweł, Pilžys, Tomaš, Garbicz, Damian, Dib, Naser, Świderska, Bianka, Matyba, Piotr, Gajewski, Zdzisław, Grzesiuk, Elżbieta, Zabielski, Romuald

“…To reveal the sources of obesity and type 2 diabetes (T2D) in humans, animal models, mainly rodents, have been used. Here, we propose a pig model of T2D…”
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Human and Arabidopsis alpha‐ketoglutarate‐dependent dioxygenase homolog proteins—New players in important regulatory processes by Marcinkowski, Michał, Pilžys, Tomaš, Garbicz, Damian, Steciuk, Jaroslaw, Zugaj, Dorota, Mielecki, Damian, Sarnowski, Tomasz J., Grzesiuk, Elżbieta

“…The family of AlkB homolog (ALKBH) proteins, the homologs of Escherichia coli AlkB 2‐oxoglutarate (2OG), and Fe(II)‐dependent dioxygenase are involved in a…”
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Inducible repair of alkylated DNA in microorganisms by Mielecki, Damian, Wrzesiński, Michał, Grzesiuk, Elżbieta

“…Alkylating agents, which are widespread in the environment, also occur endogenously as primary and secondary metabolites. Such compounds have intrinsically…”
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Unlocking the genome of the non-sourdough Kazachstania humilis MAW1: insights into inhibitory factors and phenotypic properties by Mielecki, Damian, Detman, Anna, Aleksandrzak-Piekarczyk, Tamara, Widomska, Małgorzata, Chojnacka, Aleksandra, Stachurska-Skrodzka, Anna, Walczak, Paulina, Grzesiuk, Elżbieta, Sikora, Anna

“…Ascomycetous budding yeasts are ubiquitous environmental microorganisms important in food production and medicine. Due to recent intensive genomic research,…”
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Ada response – a strategy for repair of alkylated DNA in bacteria by Mielecki, Damian, Grzesiuk, Elżbieta

“…Abstract Alkylating agents are widespread in the environment and also occur endogenously. They can be cytotoxic or mutagenic to the cells introducing alkylated…”
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Unsymmetrically Substituted Dibenzo[ b,f ][1,5]-diazocine-6,12(5 H ,11 H )dione-A Convenient Scaffold for Bioactive Molecule Design by Bieszczad, Bartosz, Garbicz, Damian, Trzybiński, Damian, Mielecki, Damian, Woźniak, Krzysztof, Grzesiuk, Elżbieta, Mieczkowski, Adam

“…A novel approach for the synthesis of unsymmetrically substituted dibenzo[ ][1,5]diazocine-6,12(5 ,11 )diones has been developed. This facile three-step method…”
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Unsymmetrically-Substituted 5,12-dihydrodibenzo[ b , f ][1,4]diazocine-6,11-dione Scaffold-A Useful Tool for Bioactive Molecules Design by Bieszczad, Bartosz, Garbicz, Damian, Trzybiński, Damian, Dudek, Marta K, Woźniak, Krzysztof, Grzesiuk, Elżbieta, Mieczkowski, Adam

“…Unsymmetrically -substituted and -disubstituted 5,12-dihydrodibenzo [ , ][1,4]diazocine-6,11-diones were synthesized in the new protocol. The desired…”
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The stilbene and dibenzo[b,f]oxepine derivatives as anticancer compounds by Garbicz, Damian, Tobiasz, Piotr, Borys, Filip, Pilżys, Tomasz, Marcinkowski, Michał, Poterała, Marcin, Grzesiuk, Elżbieta, Krawczyk, Hanna

“…That compound (4) could interact stronger with tubulin, relative to colchicine and CA-4. [Display omitted] •Cytotoxic effect of six stilbenes and three oxepine…”
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Intracellular and tissue specific expression of FTO protein in pig: changes with age, energy intake and metabolic status by Ferenc, Karolina, Pilžys, Tomaš, Garbicz, Damian, Marcinkowski, Michał, Skorobogatov, Oleksandr, Dylewska, Małgorzata, Gajewski, Zdzisław, Grzesiuk, Elżbieta, Zabielski, Romuald

“…Genome-wide association studies in the FTO gene have identified SNPs correlating with obesity and type 2 diabetes. In mice, lack of Fto function leads to…”
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Calmodulin as Ca2+-Dependent Interactor of FTO Dioxygenase by Marcinkowski, Michał, Pilžys, Tomaš, Garbicz, Damian, Piwowarski, Jan, Przygońska, Kaja, Winiewska-Szajewska, Maria, Ferenc, Karolina, Skorobogatov, Oleksandr, Poznański, Jarosław, Grzesiuk, Elżbieta

“…FTO is an N6-methyladenosine demethylase removing methyl groups from nucleic acids. Several studies indicate the creation of FTO complexes with other proteins…”
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Anticancer agents found in environment affect Daphnia at population, individual and molecular levels by Grzesiuk, Małgorzata, Bednarska, Anna, Mielecki, Damian, Garbicz, Damian, Marcinkowski, Michał, Pilžys, Tomaš, Malinowska, Agata, Świderska, Bianka, Grzesiuk, Elżbieta

“…•Medicines in concentration registered in environment affect Daphnia species.•Cyclophosphamide and cis-platin are harmful for crustaceans.•Anticancer…”
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Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues by Bieszczad, Bartosz, Garbicz, Damian, Świtalska, Marta, Dudek, Marta K, Warszycki, Dawid, Wietrzyk, Joanna, Grzesiuk, Elżbieta, Mieczkowski, Adam

“…Histone deacetylase (HDAC) inhibitors are a class of drugs used in the cancer treatment. Here, we developed a library of 19 analogues of Vorinostat, an HDAC…”
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Replacing centrifugation with mixing in urine analysis enriches protein pool in the urine samples by Garbicz, Damian, Pilžys, Tomaš, Wiśniowski, Iga, Grzesiuk, Małgorzata, Cylke, Radosław, Kosieradzki, Maciej, Grzesiuk, Elżbieta, Piwowarski, Jan, Marcinkowski, Michał, Lisik, Wojciech

“…Urine is the basic diagnostic material, easy to collect, not requiring invasive approach. During standard procedure the urine samples are centrifuged and the…”
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Correction: How cyclophosphamide at environmentally relevant concentration influences Daphnia magna life history and its proteome by Grzesiuk, Małgorzata, Mielecki, Damian, Pilżys, Tomasz, Garbicz, Damian, Marcinkowski, Michał, Grzesiuk, Elżbieta

“…[This corrects the article DOI: 10.1371/journal.pone.0195366.]…”
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Effect of Posttranslational Modifications on the Structure and Activity of FTO Demethylase by Marcinkowski, Michał, Pilžys, Tomaš, Garbicz, Damian, Piwowarski, Jan, Mielecki, Damian, Nowaczyk, Grzegorz, Taube, Michał, Gielnik, Maciej, Kozak, Maciej, Winiewska-Szajewska, Maria, Szołajska, Ewa, Dębski, Janusz, Maciejewska, Agnieszka M, Przygońska, Kaja, Ferenc, Karolina, Grzesiuk, Elżbieta, Poznański, Jarosław

“…The FTO protein is involved in a wide range of physiological processes, including adipogenesis and osteogenesis. This two-domain protein belongs to the AlkB…”
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Differences in Intestinal Barrier Development between Intrauterine Growth Restricted and Normal Birth Weight Piglets by Olszewski, Jarosław, Zabielski, Romuald, Skrzypek, Tomasz, Matyba, Piotr, Wierzbicka, Małgorzata, Adamski, Antoni, Grzesiuk, Elżbieta, Sady, Maria, Gajewski, Zdzisław, Ferenc, Karolina

“…Intrauterine growth restricted (IUGR) piglets are born at term but have low birth mass and a characteristic shape of the head. Impaired general condition,…”
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