Search Results - "Grygorczyk, Ryszard"

Hemolysis is a primary ATP-release mechanism in human erythrocytes by Sikora, Jacek, Orlov, Sergei N., Furuya, Kishio, Grygorczyk, Ryszard

“…The hypothesis that regulated ATP release from red blood cells (RBCs) contributes to nitric oxide-dependent control of local blood flow has sparked much…”
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Effects of Hypoxia on Erythrocyte Membrane Properties-Implications for Intravascular Hemolysis and Purinergic Control of Blood Flow by Grygorczyk, Ryszard, Orlov, Sergei N

“…Intravascular hemolysis occurs in hereditary, acquired, and iatrogenic hemolytic conditions but it could be also a normal physiological process contributing to…”
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Wide field of view quantitative imaging of cellular ATP release by Tan, Ju Jing, Ponomarchuk, Olga, Grygorczyk, Ryszard, Boudreault, Francis

“…Although several mechanical stressors promote ATP secretion from eukaryotic cells, few mechanosensitive pathways for ATP release have been precisely…”
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STIM‐1 and ORAI‐1 channel mediate angiotensin‐II‐induced expression of Egr‐1 in vascular smooth muscle cells by Simo‐Cheyou, Estelle R., Tan, Ju Jing, Grygorczyk, Ryszard, Srivastava, Ashok K.

“…An upregulation of Egr‐1 expression has been reported in models of atherosclerosis and intimal hyperplasia and, various vasoactive peptides and growth…”
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Imaging and characterization of stretch‐induced ATP release from alveolar A549 cells by Grygorczyk, Ryszard, Furuya, Kishio, Sokabe, Masahiro

“…Key point Translation of mechanical forces into biological effects often involves ATP release and activation of the purinergic signalling cascade. In the…”
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Volume-sensitive release of organic osmolytes in the human lung epithelial cell line A549: role of the 5-lipoxygenase by Holm, Jacob Bak, Grygorczyk, Ryszard, Lambert, Ian Henry

“…Pathophysiological conditions challenge cell volume homeostasis and perturb cell volume regulatory mechanisms leading to alterations of cell metabolism, active…”
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Real-time imaging of inflation-induced ATP release in the ex vivo rat lung by Furuya, Kishio, Tan, Ju Jing, Boudreault, Francis, Sokabe, Masahiro, Berthiaume, Yves, Grygorczyk, Ryszard

“…Extracellular ATP and other nucleotides are important autocrine/paracrine mediators that regulate diverse processes critical for lung function, including…”
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Cell swelling-induced ATP release is tightly dependent on intracellular calcium elevations by Boudreault, Francis, Grygorczyk, Ryszard

“…Mechanical stresses release ATP from a variety of cells by a poorly defined mechanism(s). Using custom-designed flow-through chambers, we investigated the…”
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Dissociation of natriuresis and diuresis by oxytocin molecular forms in rats by Jankowski, Marek, Danalache, Bogdan A, Plante, Eric, Menaouar, Ahmed, Florian, Maria, Tan, Ju Jing, Grygorczyk, Ryszard, Broderick, Tom L, Gutkowska, Jolanta

“…In the rat, oxytocin (OT) produces dose-dependent diuretic and natriuretic responses. Post-translational enzymatic conversion of the OT biosynthetic precursor…”
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The Hydrogel Nature of Mammalian Cytoplasm Contributes to Osmosensing and Extracellular pH Sensing by Fels, Johannes, Orlov, Sergei N., Grygorczyk, Ryszard

“…Cytoplasm is thought to have many hydrogel-like characteristics, including the ability to absorb large amounts of water and change volume in response to…”
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Modulation of Extracellular ATP Content of Mast Cells and DRG Neurons by Irradiation: Studies on Underlying Mechanism of Low-Level-Laser Therapy by Shen, Xueyong, Grygorczyk, Ryszard, Hu, Lei, Wang, Lina, Schwarz, Wolfgang

“…Low-level-laser therapy (LLLT) is an effective complementary treatment, especially for anti-inflammation and wound healing in which dermis or mucus mast cells…”
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Activation of Subcutaneous Mast Cells in Acupuncture Points Triggers Analgesia by Wang, Li-Na, Wang, Xue-Zhi, Li, Yu-Jia, Li, Bing-Rong, Huang, Meng, Wang, Xiao-Yu, Grygorczyk, Ryszard, Ding, Guang-Hong, Schwarz, Wolfgang

“…This review summarizes experimental evidence indicating that subcutaneous mast cells are involved in the trigger mechanism of analgesia induced by acupuncture,…”
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Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications by Grygorczyk, Ryszard, Boudreault, Francis, Ponomarchuk, Olga, Tan, Ju, Furuya, Kishio, Goldgewicht, Joseph, Kenfack, Falonne, Yu, François

“…The lytic release of ATP due to cell and tissue injury constitutes an important source of extracellular nucleotides and may have physiological and…”
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Mechanosensitive ATP release in the lungs: New insights from real-time luminescence imaging studies by Grygorczyk, Ryszard, Boudreault, Francis, Tan, Ju Jing, Ponomarchuk, Olga, Sokabe, Masahiro, Furuya, Kishio

“…Extracellular ATP and other nucleotides are important autocrine/paracrine mediators that stimulate purinergic receptors and regulate diverse processes in the…”
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Cell deformation at the air-liquid interface induces Ca2+-dependent ATP release from lung epithelial cells by Ramsingh, Ronaldo, Grygorczyk, Alexandra, Solecki, Anna, Cherkaoui, Lalla Siham, Berthiaume, Yves, Grygorczyk, Ryszard

“…Extracellular nucleotides regulate mucociliary clearance in the airways and surfactant secretion in alveoli. Their release is exquisitely mechanosensitive and…”
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Elevation of Intracellular Na+ Contributes to Expression of Early Response Genes Triggered by Endothelial Cell Shrinkage by Shiyan, Alexandra A, Sidorenko, Svetlana V, Fedorov, Dmitry, Klimanova, Elizaveta A, Smolyaninova, Larisa V, Kapilevich, Leonid V, Grygorczyk, Ryszard, Orlov, Sergei N

“…BACKGROUND/AIMSProlonged hyperosmotic shrinkage evokes expression of osmoprotective genes via nuclear factor NFAT5-mediated pathway and activates Na+ influx…”
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Response: Hemolysis is a primary and physiologically relevant ATP release mechanism in human erythrocytes by Sikora, Jacek, Orlov, Sergei N., Furuya, Kishio, Grygorczyk, Ryszard

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Heat induces adenosine triphosphate release from mast cells in vitro: a putative mechanism for moxibustion by Hu, Lei, Wang, Lina, Wei, Jianzi, Ryszard, Grygorczyk, Shen, Xueyong, Wolfgang, Schwarz

“…To investigate the role of adenosine tri-phosphate (ATP) purinergic signaling in mast cells (MCs) modulated by heat to further understand the molecular…”
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Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells by Platonova, Alexandra, Koltsova, Svetlana V., Hamet, Pavel, Grygorczyk, Ryszard, Orlov, Sergei N.

“…Contrasting cell volume behaviours (swelling vs. shrinkage) are considered as criteria to distinguish necrosis from apoptosis. In this study, we employed a…”
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Nitric oxide signaling in oxytocin-mediated cardiomyogenesis by Danalache, Bogdan A, Paquin, Joanne, Donghao, Wang, Grygorczyk, Ryszard, Moore, Jennifer C, Mummery, Christine L, Gutkowska, Jolanta, Jankowski, Marek

“…Oxytocin (OT), a hormone recently identified in the heart, induces embryonic and cardiac somatic stem cells to differentiate into cardiomyocytes (CM), possibly…”
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