Search Results - "Gruzdev, Dmitry A"

Synthesis of Novel Planar-Chiral Charge-Compensated nido -Carborane-Based Amino Acid by Gruzdev, Dmitry A, Telegina, Angelina A, Ezhikova, Marina A, Kodess, Mikhail I, Levit, Galina L, Krasnov, Victor P

“…Amino acids with unusual types of chirality and their derivatives have recently attracted attention as precursors in the synthesis of chiral catalysts and…”
Get full text

Synthesis of Novel Carborane-Containing Derivatives of RGD Peptide by Vakhrushev, Alexander V, Gruzdev, Dmitry A, Demin, Alexander M, Levit, Galina L, Krasnov, Victor P

“…Short peptides containing the Arg-Gly-Asp (RGD) fragment can selectively bind to integrins on the surface of tumor cells and are attractive transport molecules…”
Get full text

Carborane-Containing Folic Acid bis -Amides: Synthesis and In Vitro Evaluation of Novel Promising Agents for Boron Delivery to Tumour Cells by Gruzdev, Dmitry A, Telegina, Angelina A, Levit, Galina L, Solovieva, Olga I, Gusel'nikova, Tatiana Ya, Razumov, Ivan A, Krasnov, Victor P, Charushin, Valery N

“…The design of highly selective low-toxic, low-molecular weight agents for boron delivery to tumour cells is of decisive importance for the development of boron…”
Get full text

Large Subunit of the Human Herpes Simplex Virus Terminase as a Promising Target in Design of Anti-Herpesvirus Agents by Krasnov, Victor P, Andronova, Valeriya L, Belyavsky, Alexander V, Borisevich, Sophia S, Galegov, George A, Kandarakov, Oleg F, Gruzdev, Dmitry A, Vozdvizhenskaya, Olga A, Levit, Galina L

“…Herpes simplex virus type 1 (HSV-1) is an extremely widespread pathogen characterized by recurrent infections. HSV-1 most commonly causes painful blisters or…”
Get full text

Synthesis of Pyrimidine Conjugates with 4-(6-Amino-hexanoyl)-7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine and Evaluation of Their Antiviral Activity by Krasnov, Victor P., Musiyak, Vera V., Levit, Galina L., Gruzdev, Dmitry A., Andronova, Valeriya L., Galegov, Georgii A., Orshanskaya, Iana R., Sinegubova, Ekaterina O., Zarubaev, Vladimir V., Charushin, Valery N.

“…A series of pyrimidine conjugates containing a fragment of racemic 7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine and its (S)-enantiomer attached via a…”
Get full text

Synthesis and Cytotoxic Activity of the Derivatives of N -(Purin-6-yl)aminopolymethylene Carboxylic Acids and Related Compounds by Krasnov, Victor P, Vozdvizhenskaya, Olga A, Baryshnikova, Maria A, Pershina, Alexandra G, Musiyak, Vera V, Matveeva, Tatyana V, Nevskaya, Kseniya V, Brikunova, Olga Y, Gruzdev, Dmitry A, Levit, Galina L

“…Testing a number of -[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2 -[1,4]benzoxazine in a panel of nine tumor cell lines…”
Get full text

Carborane-containing amino acids and peptides: Synthesis, properties and applications by Gruzdev, Dmitry A., Levit, Galina L., Krasnov, Victor P., Charushin, Valery N.

“…[Display omitted] •Carboranyl amino acids and peptides are mainly designed for medicinal chemistry.•Carborane moieties in the structure of amino acids /…”
Get full text

N‑Aminoacyl-3-amino-nido-carboranes as a Group of Boron-Containing Derivatives of Natural Amino Acids by Gruzdev, Dmitry A, Telegina, Angelina A, Levit, Galina L, Krasnov, Victor P

“…A new group of nido-carboranyl derivatives of natural (S)-amino acids containing from 9 to 18 boron atoms was obtained in good yields as a result of acylation…”
Get full text

Synthesis of Charge-Compensated nido-Carboranyl Derivatives of Sulfur-Containing Amino Acids and Biotin by Gruzdev, Dmitry A., Telegina, Angelina A., Levit, Galina L., Ezhikova, Marina A., Kodess, Mikhail I., Krasnov, Victor P.

“…A new group of charge-compensated nido-carboranyl derivatives of sulfur-containing amino acids and biotin has been synthesized in which the boron atom in…”
Get full text

Nonenzymatic Acylative Kinetic Resolution of Racemic Amines and Related Compounds by Krasnov, Victor P., Gruzdev, Dmitry A., Levit, Galina L.

“…Acylative kinetic resolution of racemic amines occupies a highly important place among the methods for preparation of enantio enriched or pure amines…”
Get full text

Chirality-Dependent Growth of Self-Assembled Diphenylalanine Microtubes by Zelenovskiy, Pavel S, Nuraeva, Alla S, Kopyl, Svitlana, Arkhipov, Sergey G, Vasilev, Semen G, Bystrov, Vladimir S, Gruzdev, Dmitry A, Waliczek, Mateusz, Svitlyk, Volodymyr, Shur, Vladimir Ya, Mafra, Luís, Kholkin, Andrei L

“…The difference in the crystal structure and growth kinetics of microtubes formed from l- and d-enantiomers of diphenylalanine dipeptide is investigated both…”
Get full text

Mutual Kinetic Resolution of Racemic 3,4‐Dihydro‐3‐methyl‐2H‐[1,4]benzoxazines with Acyl Chlorides of Racemic O‐Phenyllactic Acids and DFT Modelling of Transition States by Korolyova, Marina A., Vakarov, Sergey A., Kozhevnikov, Dmitry N., Gruzdev, Dmitry A., Levit, Galina L., Krasnov, Victor P.

“…The effect of the electronic nature of the para substituent on the aromatic ring of 2‐aryloxypropionyl chlorides on the stereochemical outcome of the acylation…”
Get full text

N‐[ω‐(Purin‐6‐yl)aminoalkanoyl] Derivatives of Chiral Heterocyclic Amines as Promising Anti‐Herpesvirus Agents by Krasnov, Victor P., Musiyak, Vera V., Vozdvizhenskaya, Olga A., Galegov, Georgiy A., Andronova, Valeria L., Gruzdev, Dmitry A., Chulakov, Evgeny N., Vigorov, Alexey Yu, Ezhikova, Marina A., Kodess, Mikhail I., Levit, Galina L., Charushin, Valery N.

“…Novel conjugates of 2‐aminopurine and purine containing fragments of chiral heterocyclic amines attached at position 6 of purine core via a linker, fragment of…”
Get full text

Synthesis and antimycobacterial activity of N-(2-aminopurin-6-yl) and N-(purin-6-yl) amino acids and dipeptides by Krasnov, Victor P., Vigorov, Alexey Yu, Musiyak, Vera V., Nizova, Irina A., Gruzdev, Dmitry A., Matveeva, Tatyana V., Levit, Galina L., Kravchenko, Marionella A., Skornyakov, Sergey N., Bekker, Olga B., Danilenko, Valery N., Charushin, Valery N.

“…[Display omitted] Synthetic routes to novel N-(purin-6-yl)- and N-(2-aminopurin-6-yl) conjugates with amino acids and glycine-containing dipeptides were…”
Get full text

Enzymatic synthesis of novel purine nucleosides bearing a chiral benzoxazine fragment by Eletskaya, Barbara Z., Gruzdev, Dmitry A., Krasnov, Victor P., Levit, Galina L., Kostromina, Maria A., Paramonov, Alexander S., Kayushin, Alexei L., Muzyka, Inessa S., Muravyova, Tatyana I., Esipov, Roman S., Andronova, Valeria L., Galegov, Georgiy A., Charushin, Valery N., Miroshnikov, Anatoly I., Konstantinova, Irina D.

“…A series of ribo‐ and deoxyribonucleosides bearing 2‐aminopurine as a nucleobase with 7,8‐difluoro‐ 3,4‐dihydro‐3‐methyl‐2H‐[1,4]benzoxazine (conjugated…”
Get full text

New chiral proline-based catalysts for silicon and zirconium oxides-promoted asymmetric Biginelli reaction by Titova, Yulia A., Gruzdev, Dmitry A., Fedorova, Olga V., Alisienok, Olga A., Murashkevich, Anna N., Krasnov, Victor P., Rusinov, Gennady L., Charushin, Valery N.

“…4-Hydroxy-(2 S )-prolines bearing 3,4-dihydro-2 H -1,4-benzoxazine or 1,2,3,4-tetrahydroquinoline fragments were synthesized and studied as chiral catalysts in…”
Get full text

Synthesis of purine and 2-aminopurine conjugates bearing the fragments of heterocyclic amines at position 6 by Gruzdev, Dmitry A., Musiyak, Vera V., Chulakov, Evgeny N., Levit, Galina L., Krasnov, Victor P.

“…A series of novel N -(purin-6-yl)- and N -(2-aminopurin-6-yl) derivatives of heterocyclic amines was synthesized. It was found that preferred preparative…”
Get full text

Synthesis of purine conjugates with bis-carboranyl derivatives of (S)-lysine or (S)-glutamic acid by Gruzdev, Dmitry A., Chulakov, Evgeny N., Levit, Galina L., Krasnov, Victor P.

“…[Display omitted] A number of new purine and 2-aminopurine conjugates with closo- or nido-carborane fragments attached via polyfunctional amino acid residues…”
Get full text

Synthesis of closo- and nido-carborane derivatives of the KRGD peptide by Gruzdev, Dmitry A., Vakhrushev, Alexander V., Demin, Alexander M., Baryshnikova, Maria A., Levit, Galina L., Krasnov, Victor P., Charushin, Valery N.

“…•A method for the synthesis of KRGD peptide derivatives containing two closo‑ or nido‑carborane residues has been developed.•A water-soluble conjugate of the…”
Get full text

Synthesis and Cytotoxic Activity of the Derivatives of IN/I-aminopolymethylene Carboxylic Acids and Related Compounds by Krasnov, Victor P, Vozdvizhenskaya, Olga A, Baryshnikova, Maria A, Pershina, Alexandra G, Musiyak, Vera V, Matveeva, Tatyana V, Nevskaya, Kseniya V, Brikunova, Olga Y, Gruzdev, Dmitry A, Levit, Galina L

“…Testing a number of N-[omega-(purin-6-yl)aminoalkanoyl] derivatives of 7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine in a panel of nine tumor cell…”
Get full text