Search Results - "Gruszka, Dennis"
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Chronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2022)“…Psychological stress has been previously reported to worsen symptoms of inflammatory bowel disease (IBD). Similarly, intestinal tertiary lymphoid organs (TLOs)…”
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IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation
Published in Journal of investigative dermatology (01-01-2022)“…Psoriasis is a common, inflammatory autoimmune skin disease. Early detection of an IFN-1 signature occurs in many psoriasis lesions, but the source of IFN…”
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A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection
Published in The Journal of immunology (1950) (01-07-2016)“…TNF-like cytokine 1A (TL1A) is expressed on APCs and provides costimulatory signals to activated lymphocytes that bear its functional receptor, death receptor…”
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A Novel Role for TL1A/DR3 in Protection Against Intestinal Injury and Infectioni, ii, iii
Published in The Journal of immunology (1950) (27-05-2016)“…Tumor necrosis factor (TNF)-like cytokine 1A (TL1A) is expressed on antigen presenting cells and provides co-stimulatory signals to activated lymphocytes that…”
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Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling
Published in JCI insight (12-03-2024)“…IL-17C is an epithelial cell-derived proinflammatory cytokine whose transcriptional regulation remains unclear. Analysis of the IL17C promoter region…”
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The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity
Published in JCI insight (18-04-2019)“…Autoimmune disease is 4 times more common in women than men. This bias is largely unexplained. Female skin is "autoimmunity prone," showing upregulation of…”
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1074 Differential Effects of Genetic Deletion of TL1A and DR3 in Crohn's Disease-Like Ileitis
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2012)Get full text
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