Search Results - "Grunlan, Melissa"
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Hydrolytic Degradation and Erosion of Polyester Biomaterials
Published in ACS macro letters (21-08-2018)“…Strategies to refine the degradation behavior of polyester biomaterials, particularly to overcome the limitations of slow hydrolytic degradation, would broaden…”
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Modern Strategies To Achieve Tissue-Mimetic, Mechanically Robust Hydrogels
Published in ACS macro letters (18-06-2019)“…Hydrogels are frequently used biomaterials due to their similarity in hydration and structure to biological tissues. However, their utility is limited by poor…”
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Protein Resistant Polymeric Biomaterials
Published in ACS macro letters (19-09-2017)“…Toward improving implantable medical devices as well as diagnostic performance, the development of polymeric biomaterials having resistance to proteins remains…”
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Smart scaffolds: shape memory polymers (SMPs) in tissue engineering
Published in Journal of materials chemistry. B, Materials for biology and medicine (03-06-2021)“…Smart scaffolds based on shape memory polymer (SMPs) have been increasingly studied in tissue engineering. The unique shape actuating ability of SMP scaffolds…”
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Double Network Hydrogels that Mimic the Modulus, Strength, and Lubricity of Cartilage
Published in Biomacromolecules (13-05-2019)“…The development of a hydrogel-based synthetic cartilage has the potential to overcome many limitations of current chondral defect treatments. Many attempts…”
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PCL-Based Shape Memory Polymer Semi-IPNs: The Role of Miscibility in Tuning the Degradation Rate
Published in Biomacromolecules (08-06-2020)“…The utility of poly(ε-caprolactone) (PCL) as a shape memory polymer (SMP) may be improved by accelerating its degradation. Recently, we have reported novel…”
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A bioactive “self-fitting” shape memory polymer scaffold with potential to treat cranio-maxillo facial bone defects
Published in Acta biomaterialia (01-11-2014)“…[Display omitted] While tissue engineering is a promising alternative for treating critical-sized cranio-maxillofacial bone defects, improvements in scaffold…”
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8
Biomedical Silicones: Leveraging Additive Strategies to Propel Modern Utility
Published in ACS macro letters (21-02-2023)“…Silicones have a long history of use in biomedical devices, with unique properties stemming from the siloxane (Si–O–Si) backbone that feature a high degree of…”
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Intrinsic osteoinductivity of PCL‐DA/PLLA semi‐IPN shape memory polymer scaffolds
Published in Journal of biomedical materials research. Part A (01-11-2021)“…Engineering osteoinductive, self‐fitting scaffolds offers a potential treatment modality to repair irregularly shaped craniomaxillofacial bone defects…”
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10
Biocompatibility and Bone Regeneration by Shape Memory Polymer Scaffolds
Published in Journal of biomedical materials research. Part A (15-10-2024)“…Biodegradable, shape memory polymer (SMP) scaffolds based on poly(ε-caprolactone) (PCL) offer unique advantages as a regenerative treatment strategy for…”
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Incorporation of a silicon-based polymer to PEG-DA templated hydrogel scaffolds for bioactivity and osteoinductivity
Published in Acta biomaterialia (01-11-2019)“…[Display omitted] A scaffold that is inherently bioactive, osteoinductive and osteoconductive may guide mesenchymal stem cells (MSCs) to regenerate bone tissue…”
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Bacteria and diatom resistance of silicones modified with PEO-silane amphiphiles
Published in Biofouling (Chur, Switzerland) (07-02-2014)“…Silicone coatings with enhanced antifouling behavior towards bacteria, diatoms, and a diatom dominated slime were prepared by incorporating PEO-silane…”
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13
Suitability of EtO sterilization for polydopamine-coated, self-fitting bone scaffolds
Published in Polymer degradation and stability (01-12-2021)“…•Shape memory scaffolds were formed by poly(ε-caprolactone) and poly(L-lactic acid).•Polydopamine-coating made scaffolds bioactive (i.e. hydroxyapatite…”
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Perspectives on Synthetic Materials to Guide Tissue Regeneration for Osteochondral Defect Repair
Published in ACS biomaterials science & engineering (10-08-2020)“…Regenerative engineering holds the potential to treat clinically pervasive osteochondral defects (OCDs). In a synthetic materials-guided approach, the…”
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Porous Poly(ε-caprolactone)–Poly(l‑lactic acid) Semi-Interpenetrating Networks as Superior, Defect-Specific Scaffolds with Potential for Cranial Bone Defect Repair
Published in Biomacromolecules (11-12-2017)“…The treatment of irregular cranial bone defects is currently limited due to the graft resorption that can occur when an ill-fitting interface exists between an…”
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16
Hydrolytic Degradation of PCL–PLLA Semi-IPNs Exhibiting Rapid, Tunable Degradation
Published in ACS biomaterials science & engineering (11-02-2019)“…Accelerating the rate of polyester hydrolytic degradation is of interest for numerous biomedical applications. Poly(ε-caprolactone) (PCL) and poly(L-lactic…”
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17
Cartilage-like tribological performance of charged double network hydrogels
Published in Journal of the mechanical behavior of biomedical materials (01-02-2021)“…A synthetic hydrogel material may offer utility as a cartilage replacement if it is able to maintain low friction in different sliding environments and achieve…”
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Emerging polymeric material strategies for cartilage repair
Published in Journal of materials chemistry. B, Materials for biology and medicine (30-11-2022)“…Cartilage is found throughout the body, serving an array of essential functions. Owing to the limited healing capacity of cartilage, damage or degeneration is…”
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19
A Glucose Biosensor Based on Phosphorescence Lifetime Sensing and a Thermoresponsive Membrane
Published in Macromolecular rapid communications. (01-05-2022)“…The adoption of existing continuous glucose monitors (CGMs) is limited by user burden. Herein, a design for a glucose biosensor with the potential for…”
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Inorganic–Organic Shape Memory Polymer (SMP) Foams with Highly Tunable Properties
Published in ACS applied materials & interfaces (09-01-2013)“…Thermoresponsive shape memory polymers (SMPs) are a class of smart materials that can return from a temporary to a permanent shape with the application of…”
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