Search Results - "Grunke, M."

Which spinal lesions are associated with new bone formation in patients with ankylosing spondylitis treated with anti-TNF agents? A long-term observational study using MRI and conventional radiography by Baraliakos, X, Heldmann, F, Callhoff, J, Listing, J, Appelboom, T, Brandt, J, Van den Bosch, F, Breban, M, Burmester, Gr, Dougados, M, Emery, P, Gaston, H, Grunke, M, Van Der Horst-Bruinsma, I E, Landewé, R, Leirisalo-Repo, M, Sieper, J, De Vlam, K, Pappas, D, Kiltz, U, Van Der Heijde, D, Braun, J

“…To study the relationship of spinal inflammation and fatty degeneration (FD) as detected by MRI and new bone formation seen on conventional radiographs (CRs)…”
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Successful treatment of inflammatory knee osteoarthritis with tumour necrosis factor blockade by Grunke, M, Schulze-Koops, H

“…Increasing evidence indicates that tumour necrosis factor (TNF) has an important role not only in inflammatory arthritis but also in degenerative joint…”
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Clinical outcomes and safety of rituximab treatment for patients with systemic lupus erythematosus (SLE) – results from a nationwide cohort in Germany (GRAID) by Witt, M, Grunke, M, Proft, F, Baeuerle, M, Aringer, M, Burmester, G, Chehab, G, Fiehn, C, Fischer-Betz, R, Fleck, M, Freivogel, K, Haubitz, M, Kötter, I, Lovric, S, Metzler, C, Rubberth-Roth, A, Schwarting, A, Specker, C, Tony, H-P, Unger, L, Wassenberg, S, Dörner, T, Schulze-Koops, H

“…ObjectiveThe objective of this article is to evaluate the safety and clinical outcome of rituximab treatment in systemic lupus erythematosus (SLE) patients…”
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Automatic face classification of Cushing's syndrome in women - a novel screening approach by Kosilek, R P, Schopohl, J, Grunke, M, Reincke, M, Dimopoulou, C, Stalla, G K, Würtz, R P, Lammert, A, Günther, M, Schneider, H J

“…Cushing's syndrome causes considerable harm to the body if left untreated, yet often remains undiagnosed for prolonged periods of time. In this study we aimed…”
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Gustatory and olfactory function in patients with granulomatosis with polyangiitis (Wegener's) by Proft, F, Steinbach, S, Dechant, C, Witt, M, Reindl, C, Schulz, S, Vielhauer, V, Hilge, R, Laubender, RP, Manger, K, Nüsslein, H, Wendler, J, Schuch, F, Schulze-Koops, H, Grunke, M

“…Objectives: Recent findings suggest that autoimmune disorders predispose to a diminished capacity to taste and smell. This has been shown for patients with…”
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Off-label biological therapies in patients with large vessel vasculitis and/or polymyalgia rheumatica : Safety and efficacy analysis of a nationwide German registry (GRAID2) by Henes, J C, Schulze-Koops, H, Witt, M, Tony, H P, Mueller, F, Grunke, M, Czihal, M, Dörner, T, Proft, F

“…To evaluate the safety and clinical outcome of biological therapies in patients with large vessel vasculitis (LVV) or polymyalgia rheumatica (PMR) refractory…”
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Information and participation in decision-making about treatment: a qualitative study of the perceptions and preferences of patients with rheumatoid arthritis by Schildmann, J, Grunke, M, Kalden, J R, Vollmann, J

“…Objectives:To elicit the perceptions and preferences of patients with rheumatoid arthritis regarding information and participation in treatment…”
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Evaluation of a Novel Semi-Automated Ultrasound System for the Detection of Synovitis: A Prospective Study involving 45 Patients with Rheumatoid Arthritis by Witt, M., Frielinghausen, J., Mueller, R., Mueller, F., Proft, F., Schulze-Koops, H., Grunke, M., Clevert, D.-A.

“…Background: Arthrosonography has proven to be more sensitive and reliable for the detection of synovitis than clinical examination, but a comprehensive…”
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Safety of 15-deoxyspergualin in the treatment of glomerulonephritis associated with active systemic lupus erythematosus by Lorenz, H-M, Grunke, M, Wendler, J, Heinzel, P A, Kalden, J R

“…Table 1 Details of the patients' history, especially previous immunosuppressive treatment, signs of SLE-GN activity or general SLE activity at entry, and…”
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Pupillary autonomic dysfunction in patients with ANCA-associated vasculitis by Moog, Philipp, Eren, O., Kossegg, S., Valda, K., Straube, A., Grünke, M., Schulze-Koops, H., Witt, M.

“…Objective To assess autonomic function by infrared dynamic pupillometry in patients with ANCA-vasculitis (AAV) in correlation to autonomic symptoms, disease…”
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Assessment of autonomic function in a cohort of patients with ANCA-associated vasculitis by Moog, P., Eren, O., Witt, M., Rauschel, V., Kossegg, S., Straube, A., Grünke, M., Schulze-Koops, H.

“…Objective To assess symptoms and objective parameters of autonomic dysfunction (AD) in patients with ANCA-associated vasculitides. Methods Symptoms and…”
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Positive influence of the Delta32CCR5 allele on response to highly active antiretroviral therapy (HAART) in HIV-1 infected patients by Kasten, S, Goldwich, A, Schmitt, M, Rascu, A, Grunke, M, Dechant, C, Kalden, J R, Harrer, T

“…The heterozygous 32 base pair deletion of the chemokine receptor 5 (Delta32CCR5) has been associated with a more benign course of HIV-1-infection. To study the…”
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A rapid and simple method for the isolation of apoptotic DNA fragments by Herrmann, M., Lorenz, H.-M., Voll, R., Griinke, M., Woith, W., Kalden, J.R.

“…We describe a simple and reproducible technique for the isolation of apoptotic DNA fragments. The method works without time consuming organic extractions and…”
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Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis by Leipe, Jan, Schramm, Markus A, Grunke, Mathias, Baeuerle, Michael, Dechant, Claudia, Nigg, Axel P, Witt, Matthias N, Vielhauer, Volker, Reindl, Christiane S, Schulze-Koops, Hendrik, Skapenko, Alla

“…To study the role of interleukin 22 (IL-22) in rheumatoid arthritis (RA). IL-22 serum levels were measured in patients with early, treatment-naive RA (n=49)…”
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In vivo blockade of TNF-alpha by intravenous infusion of a chimeric monoclonal TNF-alpha antibody in patients with rheumatoid arthritis. Short term cellular and molecular effects by Lorenz, HM, Antoni, C, Valerius, T, Repp, R, Grunke, M, Schwerdtner, N, Nusslein, H, Woody, J, Kalden, JR, Manger, B

“…Due to the unknown etiology of RA, specific treatment is not available. Recently, in a double-blinded, placebo-controlled clinical trial, in vivo blockade of…”
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Nelfinavir associated with peripheral neuropathy in an HIV-infected patient by Grunke, M, Kraetsch, H G, Löw, P, Rascu, A, Kalden, J R, Harrer, T

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15-Deoxyspergualin in patients with refractory ANCA-associated systemic vasculitis: A six-month open-label trial to evaluate safety and efficacy by BIRCK, Rainer, WARNATZ, Klaus, HOTTA, Osamu, NOWACK, Rainer, VAN DER WOUDE, Fokko J, LORENZ, Hanns M, CHOI, Mira, HAUBITZ, Marion, GRÜNKE, Mathias, PETER, Hans H, KALDEN, Joachim R, GÖBEL, Ursula, DREXLER, Johannes M

“…The combination of cyclophosphamide (CYC) and oral corticosteroids is effective in the majority of patients with antineutrophil cytoplasmic antibody-associated…”
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Initiation of HAART in drug-naive HIV type 1 patients prevents viral breakthrough for a median period of 35.5 months in 60% of the patients by Van Vaerenbergh, K, Harrer, T, Schmit, J-C, Carbonez, A, Fontaine, E, Kurowski, M, Grünke, M, Löw, P, Rascu, A, Schmidt, B, Schmitt, M, Thoelen, I, Walter, H, Van Laethem, K, Van Ranst, M, Desmyter, J, De Clercq, E, Vandamme, A-M

“…The introduction of potent combinations of antiviral drugs is a major breakthrough in the treatment of HIV. We investigated the long-term virologic outcome and…”
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Safety and efficacy of off-label use of biologic therapies in patients with inflammatory rheumatic diseases refractory to standard of care therapy : Data from a nationwide German registry (GRAID2) by Proft, F, Schulze-Koops, H, Grunke, M, Schrezenmeier, E, Halleck, F, Henes, J, Unger, L, Schmidt, E, Fiehn, C, Jacobi, A, Iking-Konert, C, Kneitz, C, Schmidt, R E, Bannert, B, Voll, R E, Fischer-Betz, R, Kötter, I, Tony, H P, Holle, J, Aringer, M, Erler, A, Behrens, F, Burmester, G R, Dörner, T

“…The German Registry of Autoimmune Diseases 2 (GRAID2) is a retrospective, non-interventional, multicenter registry study collecting data from patients with…”
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Off-label-Biologikatherapie bei Patienten mit Großgefäßvaskulitiden und/oder Polymyalgia rheumatica: Wirksamkeits- und Sicherheitsanalyse eines nationalen Registers (GRAID2) by Henes, J. C., Schulze-Koops, H., Witt, M., Tony, H. P., Mueller, F., Grunke, M., Czihal, M., Dörner, T., Proft, F.

“…Zusammenfassung Zielsetzung Retrospektive Erfassung und Evaluation der klinischen Wirksamkeit und Sicherheit von Off-label-Biologikatherapien bei Patienten mit…”
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