Search Results - "Grunicke, H."

Coordinated regulation of Ras-, Rac-, and Ca2+-dependent signaling pathways by Grunicke, Hans H

“…Stimulation of cells by a broad variety of agonists results in a coordinated activation of Ca2+-, Ras-, and Rac-dependent pathways, which have to synergize to…”
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Protein Kinase C Isoforms Involved in the Transcriptional Activation of Cyclin D1 by Transforming Ha-Ras by Kampfer, S, Windegger, M, Hochholdinger, F, Schwaiger, W, Pestell, R G, Baier, G, Grunicke, H H, Uberall, F

“…Transcriptional activation of the cyclin D1 by oncogenic Ras appears to be mediated by several pathways leading to the activation of multiple transcription…”
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Evidence That Atypical Protein Kinase C-λ and Atypical Protein Kinase C-ζ Participate in Ras-Mediated Reorganization of the F-Actin Cytoskeleton by Überall, Florian, Hellbert, Karina, Kampfer, Sonja, Maly, Karl, Villunger, Andreas, Spitaler, Martin, Mwanjewe, James, Baier-Bitterlich, Gabriele, Baier, Gottfried, Grunicke, Hans H.

“…Expression of transforming Ha-Ras L61 in NIH3T3 cells causes profound morphological alterations which include a disassembly of actin stress fibers. The…”
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Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes by Baier-Bitterlich, G, Uberall, F, Bauer, B, Fresser, F, Wachter, H, Grunicke, H, Utermann, G, Altman, A, Baier, G

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Long‐term monitoring of visually not inspectable tunnel linings using fibre optic sensing by Grunicke, Urs H., Lienhart, Werner, Vorwagner, Alois

“…Regular structural assessments of tunnel linings are commonly performed by visual inspection. Crack phenomena and their development over time are essential…”
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Sustainable Tunnelling – An infrastructure operator's, planner's, contractor's and scientist's perspective by Heissenberger, Roman, Grunicke, Urs H., Raschendorfer, Jürgen, Holzer, Clemens

“…Sustainability is a guiding principle for political, economic and ecological action, which in companies, societies and countries all over the world, is based…”
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Conventional PKC-α, Novel PKC-ε and PKC-θ, but Not Atypical PKC-λ Are MARCKS Kinases in Intact NIH 3T3 Fibroblasts by Überall, Florian, Giselbrecht, Sabine, Hellbert, Karina, Fresser, Friedrich, Bauer, Birgit, Gschwendt, Michael, Grunicke, Hans H., Baier, Gottfried

“…Phosphorylation of myristoylated alanine-rich protein kinase C substrate (MARCKS) in intact cells has been employed as an indicator for activation of protein…”
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Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance by GEKELER, V, BOER, R, GRUNICKE, H, ÜBERALL, F, ISE, W, SCHUBERT, C, UTZ, I, HOFMANN, J, SANDERS, K. H, SCHÄCHTELE, C, KLEMM, K

“…Inhibition of protein kinase C (PKC) is discussed as a new approach for overcoming multidrug resistance (MDR) in cancer chemotherapy. For evaluation of this…”
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Critical role of protein kinase C α and calcium in growth factor induced activation of the Na +/H + exchanger NHE1 by Maly, Karl, Strese, Kukka, Kampfer, Sonja, Ueberall, Florian, Baier, Gottfried, Ghaffari-Tabrizi, Nassim, Grunicke, Hans H, Leitges, Michael

“…The ubiquitously expressed Na +/H + exchanger (NHE1) plays an important role in the regulation of the intracellular pH. Induction of NHE activity by phorbol…”
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Coordinated Regulation of Ras-, Rac-, and Ca super(2+)-Dependent Signaling Pathways by Grunicke, H H

“…Stimulation of cells by a broad variety of agonists results in a coordinated activation of Ca super(2+)-, Ras-, and Rac-dependent pathways, which have to…”
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Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-λ, ϵ and ζ by Kampfer, Sonja, Hellbert, Karina, Villunger, Andreas, Doppler, Wolfgang, Baier, Gottfried, Grunicke, Hans H., Überall, Florian

“…The implication of protein kinase C (PKC) isoforms cPKC‐α, nPKC‐ϵ, aPKC‐λ and aPKC‐ζ in the transcriptional activation of a c‐fos promoter‐driven CAT‐reporter…”
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Regulation of phospholipase D isoenzymes by transforming Ras and atypical protein kinase C-iota by Mwanjewe, J, Spitaler, M, Ebner, M, Windegger, M, Geiger, M, Kampfer, S, Hofmann, J, Uberall, F, Grunicke, H H

“…The activation of phospholipase D (PLD) by transforming Ras is well documented. Although two distinct PLD isoforms, PLD1 and PLD2, have been cloned from…”
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Novel Membrane-Targeted ERK1 and ERK2 Chimeras Which Act as Dominant Negative, Isotype-Specific Mitogen-Activated Protein Kinase Inhibitors of Ras-Raf-Mediated Transcriptional Activation of c-fos in NIH 3T3 Cells by Hochholdinger, F, Baier, G, Nogalo, A, Bauer, B, Grunicke, H H, Uberall, F

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hexadecylphosphocholine inhibits inositol phosphate formation and protein kinase C activity by Uberall, F, Oberhuber, H, Maly, K, Zaknun, J, Demuth, L, Grunicke, H H

“…Hexadecylphosphocholine (HePC) inhibits protein kinase C (PKC) from NIH3T3 cells in cell-free extracts with a 50% inhibitory concentration of about 7 microM…”
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PKC-independent modulation of multidrug resistance in cells with mutant (V185) but not wild-type (G185) p-glycoprotein by bryostatin 1 by Spitaler, Martin, Utz, Irene, Hilbe, Wolfgang, Hofmann, Johann, Grunicke, HansH

“…Bryostatin 1 is a new antitumor agent which modulates the enzyme activity of protein kinase C (PKC, phospholipid-Ca 2+-dependent ATP:protein transferase, EC…”
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MDR1 causes resistance to the antitumour drug miltefosine by RYBCZYNSKA, M, LIU, R, LU, P, SHAROM, F. J, STEINFELS, E, DI PIETRO, A, SPITALER, M, GRUNICKE, H, HOFMANN, J

“…Miltefosine (hexadecylphosphocholine) is used for topical treatment of breast cancers. It has been shown previously that a high percentage of breast carcinomas…”
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Traffic tunnels – Development of a cross‐asset, reliability‐based life cycle management by Grunicke, Urs H., Stefan, Christian, van Linn, Andreas, Weninger‐Vycudil, Alfred, Mellert, Lars Derek

“…Tunnels within primary road networks are complex systems. The prerequisite of a good level of service is the seamless interaction of the various tunnel…”
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Transforming potentials of epidermal growth factor and nerve growth factor receptors inversely correlate with their phospholipase C gamma affinity and signal activation by Obermeier, A., Tinhofer, I., Grunicke, H. H., Ullrich, A.

“…The exchange of nerve growth factor receptor/Trk and epidermal growth factor receptor (EGFR) phospholipase C gamma (PLC gamma) binding sites resulted in the…”
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Signal transduction inhibitors by Grunicke, H.

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Thiazolyl and benzothiazolyl hydrazones derived from α-( N)-acetylpyridines and diazines: synthesis, antiproliferative activity and CoMFA studies by Easmon, J, Heinisch, G, Hofmann, J, Langer, T, Grunicke, HH, Fink, J, Pürstinger, G

“…The synthesis of a series of thiazolyl and benzothiazolyl hydrazones derived from α-( N)-acylpyridines, -quinolines, -isoquinolines, -pyridazines,…”
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