Search Results - "Grundy, Laura J"

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  1. 1

    dictionary of behavioral motifs reveals clusters of genes affecting Caenorhabditis elegans locomotion by Brown, André E. X., Yemini, Eviatar I., Grundy, Laura J., Jucikas, Tadas, Schafer, William R.

    “…Visible phenotypes based on locomotion and posture have played a critical role in understanding the molecular basis of behavior and development in…”
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  2. 2
  3. 3

    Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans by Cho, Yongmin, Porto, Daniel A, Hwang, Hyundoo, Grundy, Laura J, Schafer, William R, Lu, Hang

    Published in Lab on a chip (07-08-2017)
    “…C. elegans is a useful genetic model system for investigating mechanisms involved in sensory behavior which are potentially relevant to human diseases. While…”
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  4. 4

    Changes in Postural Syntax Characterize Sensory Modulation and Natural Variation of C. elegans Locomotion by Schwarz, Roland F, Branicky, Robyn, Grundy, Laura J, Schafer, William R, Brown, André E X

    Published in PLoS computational biology (01-08-2015)
    “…Locomotion is driven by shape changes coordinated by the nervous system through time; thus, enumerating an animal's complete repertoire of shape transitions…”
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  5. 5

    PACRG, a protein linked to ciliary motility, mediates cellular signaling by Loucks, Catrina M, Bialas, Nathan J, Dekkers, Martijn P J, Walker, Denise S, Grundy, Laura J, Li, Chunmei, Inglis, P Nick, Kida, Katarzyna, Schafer, William R, Blacque, Oliver E, Jansen, Gert, Leroux, Michel R

    Published in Molecular biology of the cell (01-07-2016)
    “…Cilia are microtubule-based organelles that project from nearly all mammalian cell types. Motile cilia generate fluid flow, whereas nonmotile (primary) cilia…”
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  6. 6

    EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling by Loucks, Catrina M, Park, Kwangjin, Walker, Denise S, McEwan, Andrea H, Timbers, Tiffany A, Ardiel, Evan L, Grundy, Laura J, Li, Chunmei, Johnson, Jacque-Lynne, Kennedy, Julie, Blacque, Oliver E, Schafer, William, Rankin, Catharine H, Leroux, Michel R

    Published in eLife (27-02-2019)
    “…Neurons throughout the mammalian brain possess non-motile cilia, organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles…”
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  7. 7

    A database of Caenorhabditis elegans behavioral phenotypes by Yemini, Eviatar, Jucikas, Tadas, Grundy, Laura J, Brown, André E X, Schafer, William R

    Published in Nature methods (01-09-2013)
    “…A growing collection of segmented and feature-extracted videos recording locomotive behavior in hundreds of C. elegans mutant strains is made available for…”
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  8. 8

    The diverse functions of the DEG/ENaC family: linking genetic and physiological insights by Kaulich, Eva, Grundy, Laura J., Schafer, William R., Walker, Denise S.

    Published in The Journal of physiology (01-05-2023)
    “…The DEG/ENaC family of ion channels was defined based on the sequence similarity between degenerins (DEG) from the nematode Caenorhabditis elegans and subunits…”
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  9. 9

    Neuropeptides encoded by nlp-49 modulate locomotion, arousal and egg-laying behaviours in Caenorhabditis elegans via the receptor SEB-3 by Chew, Yee Lian, Grundy, Laura J., Brown, André E. X., Beets, Isabel, Schafer, William R.

    “…Neuropeptide signalling has been implicated in a wide variety of biological processes in diverse organisms, from invertebrates to humans. The Caenorhabditis…”
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  10. 10

    Neuropeptides encoded by nlp-49 modulate locomotion, arousal and egg-laying behaviours in Caenorhabditis elegans via the receptor SEB-3 by Chew, Yee Lian, Grundy, Laura J., Brown, André E. X., Beets, Isabel, Schafer, William R.

    “…Neuropeptide signalling has been implicated in a wide variety of biological processes in diverse organisms, from invertebrates to humans. The Caenorhabditis…”
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    Journal Article
  11. 11

    A database of C. elegans behavioral phenotypes by Yemini, Eviatar, Jucikas, Tadas, Grundy, Laura J., Brown, André E.X., Schafer, William R.

    Published in Nature methods (14-07-2013)
    “…Using low-cost automated tracking microscopes, we have generated a behavioral database for 305 C. elegans strains, including 76 mutants with no previously…”
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  12. 12

    Changes in Postural Syntax Characterize Sensory Modulation and Natural Variation of C . elegans Locomotion: e1004322 by Schwarz, Roland F, Branicky, Robyn, Grundy, Laura J, Schafer, William R, Brown, André EX

    Published in PLoS computational biology (01-08-2015)
    “…Locomotion is driven by shape changes coordinated by the nervous system through time; thus, enumerating an animal's complete repertoire of shape transitions…”
    Get full text
    Journal Article