Search Results - "Grundtman, C"

A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies by Dastmalchi, M, Grundtman, C, Alexanderson, H, Mavragani, C P, Einarsdottir, H, Helmers, S Barbasso, Elvin, K, Crow, M K, Nennesmo, I, Lundberg, I E

“…To investigate the effect of the tumour necrosis factor (TNF) blocking agent infliximab in patients with treatment-resistant inflammatory myopathies. A total…”
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Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis by Korotkova, M, Helmers, S Barbasso, Loell, I, Alexanderson, H, Grundtman, C, Dorph, C, Lundberg, I E, Jakobsson, P-J

“…To investigate the expression of microsomal prostaglandin E (PGE) synthase 1 (mPGES-1) and cyclooxygenase (COX) in muscle biopsies from patients with…”
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Effects of adalimumab treatment on endothelial cell activation markers in the skeletal muscle of patients with rheumatoid arthritis by Bergström, Ulf, Grundtman, Cecilia, Lundberg, Ingrid E, Jacobsson, Lennart T H, Nilsson, Käth, Turesson, Carl

“…Patients with rheumatoid arthritis (RA), particularly those with severe disease, have increased risk of cardiovascular disease (CVD). Previous studies suggest…”
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Systemic tnf-blocking therapy does not modulate the synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients by Sundberg, E., Grundtman, C., Klint, E. A. F., Lindberg, J., Emestam, S., Ulfgren, A., Harris, H. Eriandsson, Andersson, U.

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The Immunology of Fibrosis by Wick, Georg, Grundtman, Cecilia, Mayerl, Christina, Wimpissinger, Thomas-Florian, Feichtinger, Johann, Zelger, Bettina, Sgonc, Roswitha, Wolfram, Dolores

“…Fibrosis is the production of excessive amounts of connective tissue, i.e., scar formation, in the course of reactive and reparative processes. Fibrosis…”
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The role of heat shock proteins in atherosclerosis by Wick, Georg, Jakic, Bojana, Buszko, Maja, Wick, Marius C., Grundtman, Cecilia

“…Key Points Humoral and cellular immunity against bacterial and parasitic heat shock protein (HSP)60 is normal, but bona fide autoimmunity is also possible…”
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Heat Shock Protein 60 and Immune Inflammatory Responses in Atherosclerosis by Grundtman, Cecilia, Kreutmayer, Simone B, Almanzar, Giovanni, Wick, Marius C, Wick, Georg

“…Hallmarks of inflammation in various cardiovascular diseases, notably atherosclerosis, have been observed for a long time. However, evidence for an…”
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TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis by Zong, Mei, Bruton, Joseph D, Grundtman, Cecilia, Yang, Huan, Li, Jian Hua, Alexanderson, Helene, Palmblad, Karin, Andersson, Ulf, Harris, Helena E, Lundberg, Ingrid E, Westerblad, Håkan

“…Polymyositis and dermatomyositis are characterised by muscle weakness and fatigue even in patients with normal muscle histology via unresolved pathogenic…”
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Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies by Grundtman, Cecilia, Bruton, Joseph, Yamada, Takashi, Östberg, Therese, Pisetsky, David S, Harris, Helena Erlandsson, Andersson, Ulf, Lundberg, Ingrid E, Westerblad, Håkan

“…Idiopathic inflammatory myopathies (IIMs) are heterogeneous rheumatic disorders of unknown cause characterized by muscle weakness, inflammatory cell…”
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A longitudinal, integrated, clinical, histological and mRNA profiling study of resistance exercise in myositis by Nader, Gustavo A, Dastmalchi, Maryam, Alexanderson, Helene, Grundtman, Cecilia, Gernapudi, Ramkishore, Esbjörnsson, Mona, Wang, Zuyi, Rönnelid, Johan, Hoffman, Eric P, Nagaraju, Kanneboyina, Lundberg, Ingrid E

“…Polymyositis and dermatomyositis are orphan, chronic skeletal muscle disorders characterized by weakness, infiltrations by mononuclear inflammatory cells, and…”
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Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies by Grundtman, Cecilia, Malmström, Vivianne, Lundberg, Ingrid E

“…Idiopathic inflammatory myopathies (IIMs), comprising polymyositis, dermatomyositis, and inclusion-body myositis, are characterized by inflammatory cell…”
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Transcatheter Embolization for the Management of Acute Active Inferior Epigastric Artery Hemorrhages by Wick, Marius C., Klocker, Josef, Grundtman, Cecilia, Jaschke, Werner, Chemelli, Andreas P.

“…Purpose To report a retrospective review of all patients who were admitted to the interventional radiology unit at our hospital for transcatheter arterial…”
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Developments in the scientific and clinical understanding of inflammatory myopathies by Lundberg, Ingrid E, Grundtman, Cecilia

“…The idiopathic inflammatory myopathies are chronic autoimmune disorders sharing the clinical symptom of muscle weakness and, in typical cases, inflammatory…”
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The pattern of acute injuries in patients from alpine skiing accidents has changed during 2000–2011: analysis of clinical and radiological data at a level I trauma center by Wick, Marius C., Dallapozza, Christian, Lill, Markus, Grundtman, Cecilia, Chemelli-Steingruber, Iris E., Rieger, Michael

“…Objectives During the last decade, many educational efforts and technological improvements have been made to protect skiing athletes from injuries. Whether…”
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Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study by Sundberg, Erik, Grundtman, Cecilia, Af Klint, Erik, Lindberg, Johan, Ernestam, Sofia, Ulfgren, Ann-Kristin, Harris, Helena Erlandsson, Andersson, Ulf

“…High-mobility group box chromosomal protein 1 (HMGB1) has recently been identified as an endogenous mediator of arthritis. TNF and IL-1beta, pivotal cytokines…”
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Vascular involvement in the pathogenesis of idiopathic inflammatory myopathies by Grundtman, Cecilia, Lundberg, Ingrid E.

“…The identification of the exact role of the involvement of the vascular system in the pathogenesis of idiopathic inflammatory myopathies (IIMs) has been the…”
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Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle by Salomonsson, Stina, Grundtman, Cecilia, Zhang, Shi-Jin, Lanner, Johanna T., Li, Charles, Katz, Abram, Wedderburn, Lucy R., Nagaraju, Kanneboyina, Lundberg, Ingrid E., Westerblad, Håkan

“…Expression of major histocompatibility complex (MHC) class I in skeletal muscle fibers is an early and consistent finding in inflammatory myopathies. To test…”
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The time-averaged inflammatory disease activity estimates the progression of erosions in MRI of the sacroiliac joints in ankylosing spondylitis by Wick, Marius C., Grundtman, Cecilia, Weiss, Rüdiger J., Gruber, Johann, Kastlunger, Martin, Jaschke, Werner, Klauser, Andrea S.

“…A method to estimate the individual ankylosing spondylitis (AS) patient radiological progression of semi-quantitative magnetic resonance imaging (MRI) changes…”
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Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis by Makrygiannakis, Dimitrios, Revu, Shankar, Neregård, Petra, af Klint, Erik, Snir, Omri, Grundtman, Cecilia, Catrina, Anca Irinel

“…Rheumatoid arthritis (RA) is characterized by synovial inflammation with local accumulation of mononuclear cells such as macrophages and lymphocytes. We…”
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Pathogenesis of idiopathic inflammatory myopathies by Grundtman, Cecilia, Lundberg, Ingrid E

“…The idiopathic inflammatory myopathies, myositis, are characterized by a chronic course with decreased muscle endurance and by infiltrates of T lymphocytes and…”
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