Search Results - "Grundschober, Eva"

Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia by Kollmann, Sebastian, Grundschober, Eva, Maurer, Barbara, Warsch, Wolfgang, Grausenburger, Reinhard, Edlinger, Leo, Huuhtanen, Jani, Lagger, Sabine, Hennighausen, Lothar, Valent, Peter, Decker, Thomas, Strobl, Birgit, Mueller, Mathias, Mustjoki, Satu, Hoelbl-Kovacic, Andrea, Sexl, Veronika

“…Deregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway is found in cancer with STAT5A/B controlling…”
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STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion by Gotthardt, Dagmar, Putz, Eva M, Grundschober, Eva, Prchal-Murphy, Michaela, Straka, Elisabeth, Kudweis, Petra, Heller, Gerwin, Bago-Horvath, Zsuzsanna, Witalisz-Siepracka, Agnieszka, Cumaraswamy, Abbarna A, Gunning, Patrick T, Strobl, Birgit, Müller, Mathias, Moriggl, Richard, Stockmann, Christian, Sexl, Veronika

“…Natural killer (NK) cells are tightly regulated by the JAK-STAT signaling pathway and cannot survive in the absence of STAT5. We now report that…”
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A kinase-independent role for CDK8 in BCR-ABL1+ leukemia by Menzl, Ingeborg, Zhang, Tinghu, Berger-Becvar, Angelika, Grausenburger, Reinhard, Heller, Gerwin, Prchal-Murphy, Michaela, Edlinger, Leo, Knab, Vanessa M., Uras, Iris Z., Grundschober, Eva, Bauer, Karin, Roth, Mareike, Skucha, Anna, Liu, Yao, Hatcher, John M., Liang, Yanke, Kwiatkowski, Nicholas P., Fux, Daniela, Hoelbl-Kovacic, Andrea, Kubicek, Stefan, Melo, Junia V., Valent, Peter, Weichhart, Thomas, Grebien, Florian, Zuber, Johannes, Gray, Nathanael S., Sexl, Veronika

“…Cyclin-dependent kinases (CDKs) are frequently deregulated in cancer and represent promising drug targets. We provide evidence that CDK8 has a key role in…”
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Adding a new facet to STAT5 in CML: Multitasking for leukemic cells by Warsch, Wolfgang, Grundschober, Eva, Sexl, Veronika

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STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia by Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Gille, Lars, Cerny-Reiterer, Sabine, Tigan, Anca-Sarmiza, Hoelbl-Kovacic, Andrea, Valent, Peter, Moriggl, Richard, Sexl, Veronika

“…We recently reported that chronic myeloid leukaemia (CML) patients harbour high levels of STAT5 when they progress to advanced phases of disease. Advanced…”
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Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1 by Edlinger, Leo, Berger‐Becvar, Angelika, Menzl, Ingeborg, Hoermann, Gregor, Greiner, Georg, Grundschober, Eva, Bago‐Horvath, Zsuzsanna, Al‐Zoughbi, Wael, Hoefler, Gerald, Brostjan, Christine, Gille, Lars, Moriggl, Richard, Spittler, Andreas, Sexl, Veronika, Hoelbl‐Kovacic, Andrea

“…Summary The p21‐activated kinases (PAKs) are key nodes in oncogenic signalling pathways controlling growth, survival, and motility of cancer cells. Their…”
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Expansion of BCR / ABL 1 + cells requires PAK 2 but not PAK 1 by Edlinger, Leo, Berger‐Becvar, Angelika, Menzl, Ingeborg, Hoermann, Gregor, Greiner, Georg, Grundschober, Eva, Bago‐Horvath, Zsuzsanna, Al‐Zoughbi, Wael, Hoefler, Gerald, Brostjan, Christine, Gille, Lars, Moriggl, Richard, Spittler, Andreas, Sexl, Veronika, Hoelbl‐Kovacic, Andrea

“…Summary The p21‐activated kinases ( PAK s) are key nodes in oncogenic signalling pathways controlling growth, survival, and motility of cancer cells. Their…”
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STAT5BN642H is a driver mutation for T cell neoplasia by Pham, Ha Thi Thanh, Maurer, Barbara, Prchal-Murphy, Michaela, Grausenburger, Reinhard, Grundschober, Eva, Javaheri, Tahereh, Nivarthi, Harini, Boersma, Auke, Kolbe, Thomas, Elabd, Mohamed, Halbritter, Florian, Pencik, Jan, Kazemi, Zahra, Grebien, Florian, Hengstschläger, Markus, Kenner, Lukas, Kubicek, Stefan, Farlik, Matthias, Bock, Christoph, Valent, Peter, Müller, Mathias, Rülicke, Thomas, Sexl, Veronika, Moriggl, Richard

“…STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and lymphoma…”
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STAT5[B.sup.N642H] is a driver mutation for T cell neoplasia by Pham, Ha Thi Thanh, Maurer, Barbara, Prchal-Murphy, Michaela, Grausenburger, Reinhard, Grundschober, Eva, Javaheri, Tahereh, Nivarthi, Harini, Boersma, Auke, Kolbe, Thomas, Elabd, Mohamed, Halbritter, Florian, Pencik, Jan, Kazemi, Zahra, Grebien, Florian, Hengstschlager, Markus, Kenner, Lukas, Kubicek, Stefan, Farlik, Matthias, Bock, Christoph, Valent, Peter, Muller, Mathias, Rulicke, Thomas, Sexl, Veronika, Moriggl, Richard

“…STAT5B is often mutated in hematopoietic malignancies. The most frequent STAT5B mutation, Asp642His (N642H), has been found in over 90 leukemia and lymphoma…”
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Declined presentation by Sexl, Veronika, Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Höfling, Lukas, Moriggl, Richard, Hölbl-Kovacic, Andrea

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STAT5 - a central player in BCR/ABL+ leukemia by Sexl, Veronika, Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Höfling, Lukas, Hölbl-Kovacic, Andrea, Moriggl, Richard

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Declined presentation: STAT5 - A central player in BCR/ABL+ Leukemia by Sexl, Veronika, Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Höfling, Lukas, Moriggl, Richard, Hölbl-Kovacic, Andrea

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The transcription factor STAT5 drives mutation and imatinib resistance in chronic myeloid leukemia via ROS production by Grundschober, Eva, Warsch, Wolfgang, Sexl, Veronika

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