Resource costing for multinational neurologic clinical trials: methods and results

We present the results of a multinational resource costing study for a prospective economic evaluation of a new medical technology for treatment of subarachnoid hemorrhage within a clinical trial. The study describes a framework for the collection and analysis of international resource cost data tha...

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Bibliographic Details
Published in:	Health economics Vol. 7; no. 7; pp. 629 - 638
Main Authors:	Schulman, Kevin, Burke, Jennifer, Drummond, Michael, Davies, Linda, Carlsson, Per, Gruger, Jans, Harris, Anthony, Lucioni, Carlo, Gisbert, Ramon, Llana, Ted, Tom, Eric, Bloom, Bernard, Willke, Richard, Glick, Henry
Format:	Journal Article
Language:	English
Published:	Chichester Wiley Subscription Services, Inc., A Wiley Company 01-11-1998 John Wiley & Sons, Ltd
Series:	Health Economics
Subjects:	Australia Clinical trials Clinical Trials as Topic - economics cost effectiveness cost identification Costing Costs and Cost Analysis Crossnational studies Data Collection - economics economics Europe Health Care Costs - statistics & numerical data Health Resources - economics Humans international health systems Marketing of Health Services Medical technology MEDICIN MEDICINE Multicenter Studies as Topic - economics Subarachnoid haemorrhage Subarachnoid Hemorrhage - economics Subarachnoid Hemorrhage - therapy technology assessment Treatment Australia Europe economics technology assessment international health systems cost effectiveness cost identification
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Summary:	We present the results of a multinational resource costing study for a prospective economic evaluation of a new medical technology for treatment of subarachnoid hemorrhage within a clinical trial. The study describes a framework for the collection and analysis of international resource cost data that can contribute to a consistent and accurate intercountry estimation of cost. Of the 15 countries that participated in the clinical trial, we collected cost information in the following seven: Australia, France, Germany, the UK, Italy, Spain, and Sweden. The collection of cost data in these countries was structured through the use of worksheets to provide accurate and efficient cost reporting. We converted total average costs to average variable costs and then aggregated the data to develop study unit costs. When unit costs were unavailable, we developed an index table, based on a market‐basket approach, to estimate unit costs. To estimate the cost of a given procedure, the market‐basket estimation process required that cost information be available for at least one country. When cost information was unavailable in all countries for a given procedure, we estimated costs using a method based on physician‐work and practice‐expense resource‐based relative value units. Finally, we converted study unit costs to a common currency using purchasing power parity measures. Through this costing exercise we developed a set of unit costs for patient services and per diem hospital services. We conclude by discussing the implications of our costing exercise and suggest guidelines to facilitate more effective multinational costing exercises. © 1998 John Wiley & Sons, Ltd.
Bibliography:	istex:2947461E4D2DE2C157245FCE6ED24446A450E4CC ark:/67375/WNG-4HVL5LR3-4 ArticleID:HEC378 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1057-9230 1099-1050 1099-1050
DOI:	10.1002/(SICI)1099-1050(1998110)7:7<629::AID-HEC378>3.0.CO;2-N