Search Results - "Gruet, Michael"

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma by Nijhuis, Anke, Sikka, Arti, Yogev, Orli, Herendi, Lili, Balcells, Cristina, Ma, Yurui, Poon, Evon, Eckold, Clare, Valbuena, Gabriel N., Xu, Yuewei, Liu, Yusong, da Costa, Barbara Martins, Gruet, Michael, Wickremesinghe, Chiharu, Benito, Adrian, Kramer, Holger, Montoya, Alex, Carling, David, Want, Elizabeth J., Jamin, Yann, Chesler, Louis, Keun, Hector C.

“…Neuroblastoma is the most common paediatric solid tumour and prognosis remains poor for high-risk cases despite the use of multimodal treatment. Analysis of…”
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Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma by Xu, Yuewei, Spear, Sarah, Ma, Yurui, Lorentzen, Marc P., Gruet, Michael, McKinney, Flora, Xu, Yitao, Wickremesinghe, Chiharu, Shepherd, Madelen R., McNeish, Iain, Keun, Hector C., Nijhuis, Anke

“…Ovarian high-grade serous carcinoma (HGSC) is the most common subtype of ovarian cancer with limited therapeutic options and a poor prognosis. In recent years,…”
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Chemical tools for profiling the intracellular ADP-ribosylated proteome by Draganov, Simeon D, Gruet, Michael J, Conole, Daniel, Balcells, Cristina, Siskos, Alexandros P, Keun, Hector C, Haskard, Dorian O, Tate, Edward W

“…The post-translational modification (PTM) ADP-ribosylation plays an important role in cell signalling and regulating protein function and has been implicated…”
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β2-Adrenergic Signalling Promotes Cell Migration by Upregulating Expression of the Metastasis-Associated Molecule LYPD3 by Gruet, Michael, Cotton, Daniel, Coveney, Clare, Boocock, David J, Wagner, Sarah, Komorowski, Lucie, Rees, Robert C, Pockley, A Graham, Garner, A Christopher, Wallis, John D, Miles, Amanda K, Powe, Desmond G

“…Metastasis is associated with poor prognosis in breast cancer. Although some studies suggest beta-blockers increase survival by delaying metastasis, others…”
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Abstract B096: Targeting RNA splicing factor RBM39 improves therapy responses in ovarian high-grade serous carcinoma by Xu, Yuewei, Spear, Sarah, Ma, Yurui, Lorentzen, Marc, Gruet, Michael, McKinney, Flora, Xu, Yitao, Wickremesinghe, Chiharu, McNeish, Iain, Keun, Hector, Nijhuis, Anke

“…Abstract Ovarian high-grade serous carcinoma (HGSC) is the most common subtype of ovarian cancer with limited therapeutic options and poor prognosis. In recent…”
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