Search Results - "Grudman, Steven"

Optimal selection of suitable templates in protein interface prediction by Grudman, Steven, Fajardo, J Eduardo, Fiser, Andras

“…Abstract Motivation Molecular-level classification of protein–protein interfaces can greatly assist in functional characterization and rational drug design…”
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INTERCAAT: identifying interface residues between macromolecules by Grudman, Steven, Fajardo, J Eduardo, Fiser, Andras

“…Abstract Summary The Interface Contact definition with Adaptable Atom Types (INTERCAAT) was developed to determine the atomic interactions between molecules…”
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Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies by Aranda-Orgilles, Beatriz, Chion-Sotinel, Isabelle, Skinner, Jordan, Grudman, Steven, Mumford, Ben, Dixon, Chantel, Postigo Fernandez, Jorge, Erler, Piril, Duchateau, Phillipe, Gouble, Agnes, Galetto, Roman, Poirot, Laurent

“…Despite the remarkable success of autologous chimeric antigen receptor (CAR) T cells, some patients relapse due to tumor antigen escape and low or uneven…”
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Abstract 551: UCART20x22: First allogeneic dual CAR T-cell therapy for the treatment of B-cell malignancies by Aranda-Orgilles, Beatriz, Chion-Sotinel, Isabelle, Grudman, Steven, Mumford, Ben, Dixon, Chantel, Galetto, Roman, Gouble, Agnes, Poirot, Laurent

“…Autologous CAR T-cell therapies have been transformative in the treatment of selected blood cancers. Despite this remarkable success, common mechanisms of…”
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Multi-armored allogeneic MUC1 CAR T cells enhance efficacy and safety in triple-negative breast cancer by Erler, Piril, Kurcon, Tomasz, Cho, Hana, Skinner, Jordan, Dixon, Chantel, Grudman, Steven, Rozlan, Sandra, Dessez, Emilie, Mumford, Ben, Jo, Sumin, Boyne, Alex, Juillerat, Alexandre, Duchateau, Philippe, Poirot, Laurent, Aranda-Orgilles, Beatriz

“…Solid tumors, such as triple-negative breast cancer (TNBC), are biologically complex due to cellular heterogeneity, lack of tumor-specific antigens, and an…”
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